3-CHLOROBENZHYDRAZIDE

Product Name: 3-CHLOROBENZHYDRAZIDE
CAS No.: 1673-47-8
Chemical Name: 3-CHLOROBENZHYDRAZIDE
Synonyms: RMA-106;ASISCHEM D51116;AKOS BBS-00004508;SPECS AN-068/40169986;3-CHLOROBENZHYDRAZIDE;3-chlorobenzohydrazide;3-Chlorobenzoylhydrazine;3-CHLOROBENZOIC HYDRAZIDE;3-Chlorobenzohydrazide >3-Chlorobenzhydrazide, 98+%
CBNumber: CB2424392
Molecular Formula: C7H7ClN2O
Formula Weight: 170.6
MOL File: 1673-47-8.mol

More

Less

3-CHLOROBENZHYDRAZIDE Property

Melting point:: 155-156°C
Density: 1.323±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: powder to crystal
pka: 11.86±0.10(Predicted)
color: White to Light yellow
BRN: 973243
InChI: InChI=1S/C7H7ClN2O/c8-6-3-1-2-5(4-6)7(11)10-9/h1-4H,9H2,(H,10,11)
InChIKey: PHRDZSRVSVNQRN-UHFFFAOYSA-N
SMILES: C(NN)(=O)C1=CC=CC(Cl)=C1
CAS DataBase Reference: 1673-47-8(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
HazardClass: IRRITANT
HS Code: 29280090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: C2648
Product name: 3-Chlorobenzohydrazide
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $33
Updated: 2025/07/31

TCI Chemical

Product number: C2648
Product name: 3-Chlorobenzohydrazide
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $112
Updated: 2025/07/31

Usbiological

Product number: 270581
Product name: 3-Chlorobenzohydrazide
Packaging: 5g
Price: $317
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC61152
Product name: 3-Chlorobenzhydrazide
Packaging: 50g
Price: $291
Updated: 2021/12/16

ChemScene

Product number: CS-W010776
Product name: 3-Chlorobenzohydrazide
Purity: >97.0%
Packaging: 100g
Price: $184
Updated: 2021/12/16

More

Less

3-CHLOROBENZHYDRAZIDE Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Antimicrobial activity

3-Chlorobenzhydrazide is a dihedral molecule that can be classified as an antibacterial and antimycobacterial agent. The crystal x-ray diffraction study revealed that 3-chlorobenzhydrazide forms a hydrogen bond with hydroxyl groups of amino acids in proteins. This property makes it an effective antibacterial agent against Gram-positive bacteria such as staphylococci and Mycobacteria tuberculosis.

Synthesis

535-80-8

1673-47-8

General procedure for the synthesis of 3-chlorobenzhydrazide from 3-chlorobenzoic acid: a mixture of 3-chlorobenzoic acid (0.5 g, 3.19 mmol), 1,3-dicyclohexylcarbodiimide (0.72 g, 3.51 mmol), and 4-dimethylaminopyridine (0.04 g, 0.32 mmol) in ethanol was stirred for 1.5 h at room temperature. The white solid was collected by filtration and the filtrate was diluted with dichloromethane (100 mL). The organic phase was washed sequentially with 1N sodium bisulfate solution (100 mL), saturated sodium bicarbonate solution (100 mL), water (100 mL) and brine (100 mL). The organic layer was dried with anhydrous magnesium sulfate, filtered and the filtrate was concentrated under reduced pressure. The resulting crude product was dissolved in ethanol (15 mL) and hydrazine monohydrate (0.46 mL, 9.58 mmol) was added. The reaction mixture was stirred at room temperature overnight. Subsequently, the reaction mixture was concentrated to dryness under reduced pressure. The residue was purified by silica gel column chromatography with the eluent being a dichloromethane solution of 3% methanol to give 0.29 g (53% yield) of 3-chlorobenzohydrazide as a white solid.

References

[1] European Journal of Medicinal Chemistry, 2017, vol. 138, p. 396 - 406
[2] Patent: US2003/55085, 2003, A1
[3] Journal of Chemical Research, 2010, vol. 34, # 12, p. 680 - 683
[4] Journal of Chemical Research, 2011, vol. 35, # 4, p. 234 - 237
[5] Monatshefte fur Chemie, 2010, vol. 141, # 4, p. 479 - 484

3-CHLOROBENZHYDRAZIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-CHLOROBENZHYDRAZIDE Suppliers

Americas 1 Belgium 2 China 100 Europe 1 Germany 3 India 5 Japan 1 The Netherlands 1 Ukraine 1 United Kingdom 14 United States 20 Global 149

Zhengzhou kangnuochenrui Chemical Technology Co.,Ltd

Tel: 18210788515
Fax: 18210788515
Email: zhuzixin999@163.c0m
Country: China
ProdList: 2998
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7892
Advantage: 64

More

Less

View Lastest Price from 3-CHLOROBENZHYDRAZIDE manufacturers

Career Henan Chemical Co

Product: 3-CHLOROBENZHYDRAZIDE 1673-47-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-07-03

1673-47-8, 3-CHLOROBENZHYDRAZIDERelated Search:

2-Chlorobenzhydrazide,98%,o-Chlorobenzhydrazide,2-CHLOROBENZHYDRAZIDE 4-CHLOROBENZHYDRAZIDE,p-Chlorobenzhydrazide,4-Chlorobenzhydrazide, 98+% 5-BROMO-2-CHLOROBENZHYDRAZIDE 98%,5-BROMO-2-CHLOROBENZHYDRAZIDE Carbohydrazide 2,5-DICHLOROBENZHYDRAZIDE 3-CHLOROBENZHYDRAZIDE (2-AMINO-5-CHLOROBENZOYL)HYDRAZIDE 3,5-DICHLOROBENZHYDRAZIDE 3,4-DICHLOROBENZENE-1-CARBOHYDRAZIDE 4-BROMO-3-CHLOROBENZHYDRAZIDE 4-BROMO-2-CHLOROBENZHYDRAZIDE 2-BROMO-4-CHLOROBENZHYDRAZIDE 2-BROMO-5-CHLOROBENZHYDRAZIDE 3-BROMO-4-CHLOROBENZHYDRAZIDE 3-CHLORO-N'-([5-OXO-3-(TRIFLUOROMETHYL)-1,5-DIHYDRO-4H-PYRAZOL-4-YLIDEN]METHYL)BENZENECARBOHYDRAZIDE N'-Phenyl-p-chlorobenzhydrazide 3,5-DICHLORO-4-METHOXYBENZENECARBOHYDRAZIDE 1-(2-AMINO-5-CHLOROBENZOYL)-1-METHYLHYDRAZINE

SPECS AN-068/40169986

ASISCHEM D51116

3-CHLOROBENZOIC HYDRAZIDE

3-CHLOROBENZOIC ACID HYDRAZIDE

3-CHLOROBENZHYDRAZIDE

3-CHLOROBENZENE-1-CARBOHYDRAZIDE

AKOS BBS-00004508

3-chlorobenzohydrazide

3-Chlorobenzenecarbohydrazide

3-CHLOROBENZOIC HYDRAZIDE, 98+%

Benzoic acid, 3-chloro-, hydrazide

3-Chlorobenzhydrazide, 98+%

30-ethyl-33-(1-hydroxy-2-methylpropyl)-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,

3-Chlorobenzohydrazide &gt

3-Chlorobenzoylhydrazine

RMA-106

1673-47-8

Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes

Chlorine Compounds