ChemicalBook > CAS DataBase List > tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate

tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate

Product Name
tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
CAS No.
112741-49-8
Chemical Name
tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
Synonyms
tert-butyl (2R,3S)-6-oxo-2,3-diphenylmorpholine-4-carboxylate;CIVENTICHEM CV-2654;CIVENTICHEM CV-2653;2-Oxo-7a-hydroxy Clopidogrel;(5S,6R)-N-BoC-5,6-diphenyl-2-morpholinone;(2R,3S)-(-)-N-Boc-6-oxo-2,3-diphenylMorpholine;tert-butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morph;(5R,6S)-(-)-4-Boc-5,6-diphenyl-2-Morpholinone, 98%;(2R,3S)-(-)-2,3-Diphenyl-6-oxomorpholine, N-BOC protected;tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarbox
CBNumber
CB2424796
Molecular Formula
C21H23NO4
Formula Weight
353.41
MOL File
112741-49-8.mol
More
Less

tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Property

Melting point:
206 °C (dec.)(lit.)
Boiling point:
509.6±50.0 °C(Predicted)
alpha 
-87 º (c=5.5 in methylene chloride)
Density 
1.175±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Acetone (Slightly, Heated, Sonicated), Chloroform (Slightly), DMSO (Slightly, Sonicated)
form 
Solid
pka
-3.28±0.60(Predicted)
color 
White to Off-White
optical activity
[α]25/D 87°, c = 5.5 in methylene chloride
InChIKey
MRUKRSQUUNYOFK-RBUKOAKNSA-N
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
HS Code 
2934999090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
331848
Product name
(2R,3S)-(?)-N-Boc-6-oxo-2,3-diphenylmorpholine
Purity
98%
Packaging
1g
Price
$52
Updated
2023/01/07
Sigma-Aldrich
Product number
331848
Product name
(2R,3S)-(?)-N-Boc-6-oxo-2,3-diphenylmorpholine
Purity
98%
Packaging
5g
Price
$197
Updated
2023/01/07
Alfa Aesar
Product number
H60764
Product name
(5R,6S)-(-)-4-Boc-5,6-diphenyl-2-morpholinone, 98%
Packaging
1g
Price
$128.65
Updated
2024/03/01
Alfa Aesar
Product number
H60764
Product name
(5R,6S)-(-)-4-Boc-5,6-diphenyl-2-morpholinone, 98%
Packaging
5g
Price
$471.65
Updated
2024/03/01
Strem Chemicals
Product number
08-1262
Product name
(2R,3S)-6-Oxo-2,3-diphenyl-4-morpholinecarboxylic acid t-butyl ester, 98% (99% ee)
Packaging
1g
Price
$165
Updated
2024/03/01
More
Less

tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Chemical Properties,Usage,Production

Chemical Properties

tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate is Off-white Solid

Uses

Tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate is a reactant used in the preparation of (-)-Jorumycin, (-)-Renieramycin G, 3-epi-Jorumycin, and 3-epi-Renieramycin G and colla gen cross-link pyridinolines.

Uses

(2R,3S)-6-Oxo-2,3-diphenyl-4-morpholinecarboxylic Acid tert-Butyl Ester is a reactant used in the preparation of (-)-Jorumycin, (-)-Renieramycin G, 3-epi-Jorumycin, and 3-epi-Renieramycin G and collagen cross-link pyridinolines.

tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Suppliers

Canada 1 China 81 Germany 1 India 2 Switzerland 1 United Kingdom 3 United States 11 Global 100
Tianjin Derchemist Science & Technology Co., Ltd.
Tel
22-58627059 13920586291
Fax
022-58620305
Email
zdcomcon@126.com
Country
China
ProdList
3461
Advantage
50
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
ForeChem (Nantong) Technology Co.,Ltd.
Tel
513-85982855 18921614129
Fax
051385915507
Email
sales@xianxingpharm.com
Country
China
ProdList
2011
Advantage
61
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7191
Advantage
65
Shanghai Aobo pharmaceutical Technology Co., Ltd
Tel
86-21-51320499
Fax
86-21-51320368
Email
aobo@aobopharm.com
Country
China
ProdList
297
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Beijing Yisiyan Technology Research Center
Tel
010-56645598 13366904824
Fax
01062230033
Email
bjkaida@163.com
Country
China
ProdList
1637
Advantage
59
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9459
Advantage
58
Shanghai potentpharm CO.,Ltd
Tel
(86) 21 51969655
Fax
(86) 21 51969655， QQ：33109286， 263541193
Country
China
ProdList
487
Advantage
22
SynAsst Chemical.
Tel
021-60343070
Fax
021-35122006
Country
China
ProdList
12740
Advantage
55
Syncozymes (Shanghai) Co.,Ltd.
Tel
021-68187180-819 13681683526
Fax
021-68187179
Email
lchen@syncozymes.com
Country
China
ProdList
225
Advantage
55
Shanghai Witofly Chemical Co.,Ltd
Tel
Email
sales@witofly.com
Country
China
ProdList
2864
Advantage
52
Shijiazhuang Lickon PharmaTech Co., Ltd.
Tel
031185291771 13832391721
Fax
0311-67305698
Email
yaofeng2005@163.com
Country
China
ProdList
975
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Shanghai Balmxy Pharmaceutical Co., Ltd
Tel
021-24206007 13764915196
Fax
86-021-23027023
Email
sales@balmxy.com
Country
China
ProdList
6773
Advantage
55
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10276
Advantage
55
Tianjin Anhao Biological Technology Co., Ltd.
Tel
Email
sales@ahpharmatech.com
Country
China
ProdList
5734
Advantage
55
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
3A SpeedChemical Inc
Tel
21-65679720
Fax
0086-21-5186 1128
Email
service@speedchemical.com
Country
China
ProdList
604
Advantage
55
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6498
Advantage
58
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7980
Advantage
55
Guangzhou Qianguang Trade Co., Ltd.
Tel
020-39071117 18030085485
Fax
020-39071119
Email
2797782741@qq.com
Country
China
ProdList
291
Advantage
55
Shanghai GL Peptide Ltd.
Tel
+86-21-61263340; 17609490614 13764994101
Fax
021-61263399
Email
fisherwang@glschina.com
Country
China
ProdList
8466
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
WG reagent
Tel
13391486464
Fax
QQ:14748090
Email
samwjf@163.com
Country
China
ProdList
3086
Advantage
55
Shanghai SuperLan Chemcial Technique Centre
Tel
021-2022843681 15618226720
Fax
+86-21-51601218
Email
lucy@atkchemical.com
Country
China
ProdList
10270
Advantage
58
Wuxi Asia Peptide Biotechnology Limited Company
Tel
0510-83583050 13771062561
Fax
0510-83583039
Email
willsun@peptide-search.com
Country
China
ProdList
6716
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Taian Jiaye Biotechnology Co.Ltd
Tel
13127280945
Email
285424065@qq.com
Country
China
ProdList
9976
Advantage
55
Greenherbs Science and Technology Development Co., Ltd.
Tel
010-61136123
Fax
+86 (10) 8857-9127
Email
pub02@greenherbs.com.cn
Country
China
ProdList
4049
Advantage
58
Hangzhou Molcore Biopharmatech Co.,Ltd
Tel
400-711-5280 86-571-81025280
Fax
86-571-85806285
Email
sales@molcore.com
Country
China
ProdList
9967
Advantage
58
Shanghai Leefloor Industrial Co., Ltd.
Tel
021-69156110 13611751650
Fax
021-69156110
Email
leefloor2016@163.com
Country
CHINA
ProdList
296
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718 +86-13336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29791
Advantage
60
Aikon International Limited
Tel
025-66113011 18112977050
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
16027
Advantage
58
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17987
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 18016230971
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
24969
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58
Kanghua (Shanghai) New Drug Development Co., Ltd.
Tel
021-61263370 18901917034
Email
xingli@glbiochem.com
Country
China
ProdList
5637
Advantage
58
Shanghai Jifeng Biotechnology Co., Ltd.
Tel
021-61263377 15023907684
Fax
021-61263399
Email
15800684150@163.com
Country
China
ProdList
8131
Advantage
58
GL Biochem (Shanghai) Ltd.
Tel
+86-021-61263370 +86-18901917034
Country
CHINA
ProdList
3904
Advantage
58

112741-49-8, tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylateRelated Search:

Carbamic acid, [(3S,4R)-tetrahydro-4-hydroxy-3-furanyl]-, 1,1-dimethylethyl 2-Methylmorpholine Ephedrine Phenylpropanolamine Ephedrine hemihydrate (5S)-N-(tert-Butoxycarbonyl)-3,4,5,6-tetrahydro-5-phenyl-4(H)-1,4-oxazin-2-one (-)-N-METHYLEPHEDRINE (R)-2-Methyl-morpholine (5R)-3,4,5,6-Tetrahydro-5-phenyl-4(H)-1,4-oxazin-2-one L-(-)-Ephedrine tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate 2-(1-phenylethylamino)ethanol 1-N-BOC-2-METHYL MORPHOLINE BOC-L-Phenylglycinol (1R,2S)-2-Amino-1,2-diphenylethanol (S)-3-phenylmorpholine 5-Phenyl-2-morpholinone TERT-BUTYL (2S,3R)-(+)-6-OXO-2,3-DIPHENYL-4-MORPHOLINECARBOXYLATE

  • CIVENTICHEM CV-2653
  • CIVENTICHEM CV-2654
  • TERT-BUTYL (2R,3S)-(-)-6-OXO-2,3-DIPHENYL-4-MORPHOLINECARBOXYLATE
  • N-TERT-BUTOXYCARBONYL-(2R,3S)-(-)-6-OXO-2,3-DIPHENYL-4-MORPHOLINE
  • N-BOC(2R, 3S)-(-)-6-OXO-2,3-DIPHENYL-4-MORPHOLINE CARBOXYLATE
  • tert-butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morph
  • TERT-BUTYL (2R,3S)-(-)-6-OXO-2,3-DIPHENY L-4-MORPHOLINECARBOXYLATE, 99% (99% EE)
  • (2R,3S)-6-Oxo-2,3-diphenyl-morpholine-4-carboxylic acid tert-butyl ester
  • (2R,3S)-Tert-butyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate
  • (5S,6R)-N-BoC-5,6-diphenyl-2-morpholinone
  • (2R,3S)-tert-butyl (2R,3S)-6-oxo-2,3-diphenylmorpholine-4-carboxylate
  • (2R,3S)-6-Oxo-2,3-diphenyl-4-morpholinecarboxylic Acid 1,1-Dimethylethyl Ester
  • 4-Morpholinecarboxylicacid, 6-oxo-2,3-diphenyl-, 1,1-dimethylethyl ester, (2R,3S)-
  • (2R,3S)-6-Oxo-2,3-diphenyl-4-morpholinecarboxylic Acid tert-Butyl Ester,99%e.e.
  • (2R,3S)-(-)-N-Boc-6-oxo-2,3-diphenylMorpholine
  • (5R,6S)-(-)-4-Boc-5,6-diphenyl-2-Morpholinone, 98%
  • (2R,3S)-(-)-2,3-Diphenyl-6-oxomorpholine, N-BOC protected
  • tert-Butyl (2R,3S)-(-)-2,3-diphenyl-6-oxomorpholine-4-carboxylate
  • (2R,3S)-6-Oxo-2,3-diphenyl-4-morpholinecarboxylic Acid tert-Butyl Ester
  • (2<I>R</I>,3<I>S</I>)-(-)-<I>N</I>-Boc-6-oxo-2,3-diphenylMorpholine
  • 2-Oxo-7a-hydroxy Clopidogrel
  • (2R,3S)-6-Oxo-2,3-diphenyl-4-morpholinecarboxylic acid t-butyl ester, 98% (99% ee)
  • tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarbox
  • tert-butyl (2R,3S)-6-oxo-2,3-diphenylmorpholine-4-carboxylate
  • ert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
  • tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylic acid
  • 112741-49-8
  • Asymmetric Synthesis
  • Chiral Building Blocks
  • Heterocyclic Building Blocks
  • Morpholines
  • API intermediates
  • Chiral Building Blocks
  • Heterocyclic Building Blocks
  • Morpholines