ChemicalBook > CAS DataBase List > tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate

tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate

Product Name
tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
CAS No.
112741-49-8
Chemical Name
tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
Synonyms
tert-butyl (2R,3S)-6-oxo-2,3-diphenylmorpholine-4-carboxylate;CIVENTICHEM CV-2654;CIVENTICHEM CV-2653;2-Oxo-7a-hydroxy Clopidogrel;(5S,6R)-N-BoC-5,6-diphenyl-2-morpholinone;(2R,3S)-(-)-N-Boc-6-oxo-2,3-diphenylMorpholine;tert-butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morph;(5R,6S)-(-)-4-Boc-5,6-diphenyl-2-Morpholinone, 98%;(2R,3S)-(-)-2,3-Diphenyl-6-oxomorpholine, N-BOC protected;tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarbox
CBNumber
CB2424796
Molecular Formula
C21H23NO4
Formula Weight
353.41
MOL File
112741-49-8.mol
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tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Property

Melting point:
206 °C (dec.)(lit.)
Boiling point:
509.6±50.0 °C(Predicted)
alpha 
-87 º (c=5.5 in methylene chloride)
Density 
1.175±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Acetone (Slightly, Heated, Sonicated), Chloroform (Slightly), DMSO (Slightly, Sonicated)
form 
Solid
pka
-3.28±0.60(Predicted)
color 
White to Off-White
optical activity
[α]25/D 87°, c = 5.5 in methylene chloride
InChIKey
MRUKRSQUUNYOFK-RBUKOAKNSA-N
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
331848
Product name
(2R,3S)-(?)-N-Boc-6-oxo-2,3-diphenylmorpholine
Purity
98%
Packaging
1g
Price
$52
Updated
2023/01/07
Sigma-Aldrich
Product number
331848
Product name
(2R,3S)-(?)-N-Boc-6-oxo-2,3-diphenylmorpholine
Purity
98%
Packaging
5g
Price
$197
Updated
2023/01/07
Alfa Aesar
Product number
H60764
Product name
(5R,6S)-(-)-4-Boc-5,6-diphenyl-2-morpholinone, 98%
Packaging
1g
Price
$128.65
Updated
2024/03/01
Alfa Aesar
Product number
H60764
Product name
(5R,6S)-(-)-4-Boc-5,6-diphenyl-2-morpholinone, 98%
Packaging
5g
Price
$471.65
Updated
2024/03/01
Strem Chemicals
Product number
08-1262
Product name
(2R,3S)-6-Oxo-2,3-diphenyl-4-morpholinecarboxylic acid t-butyl ester, 98% (99% ee)
Packaging
1g
Price
$165
Updated
2024/03/01
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tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Chemical Properties,Usage,Production

Chemical Properties

tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate is Off-white Solid

Uses

Tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate is a reactant used in the preparation of (-)-Jorumycin, (-)-Renieramycin G, 3-epi-Jorumycin, and 3-epi-Renieramycin G and colla gen cross-link pyridinolines.

Uses

(2R,3S)-6-Oxo-2,3-diphenyl-4-morpholinecarboxylic Acid tert-Butyl Ester is a reactant used in the preparation of (-)-Jorumycin, (-)-Renieramycin G, 3-epi-Jorumycin, and 3-epi-Renieramycin G and collagen cross-link pyridinolines.

tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Suppliers

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112741-49-8, tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylateRelated Search:

Carbamic acid, [(3S,4R)-tetrahydro-4-hydroxy-3-furanyl]-, 1,1-dimethylethyl 2-Methylmorpholine Ephedrine Phenylpropanolamine Ephedrine hemihydrate (5S)-N-(tert-Butoxycarbonyl)-3,4,5,6-tetrahydro-5-phenyl-4(H)-1,4-oxazin-2-one (-)-N-METHYLEPHEDRINE (R)-2-Methyl-morpholine (5R)-3,4,5,6-Tetrahydro-5-phenyl-4(H)-1,4-oxazin-2-one L-(-)-Ephedrine tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate 2-(1-phenylethylamino)ethanol 1-N-BOC-2-METHYL MORPHOLINE BOC-L-Phenylglycinol (1R,2S)-2-Amino-1,2-diphenylethanol (S)-3-phenylmorpholine 5-Phenyl-2-morpholinone TERT-BUTYL (2S,3R)-(+)-6-OXO-2,3-DIPHENYL-4-MORPHOLINECARBOXYLATE

  • CIVENTICHEM CV-2653
  • CIVENTICHEM CV-2654
  • TERT-BUTYL (2R,3S)-(-)-6-OXO-2,3-DIPHENYL-4-MORPHOLINECARBOXYLATE
  • N-TERT-BUTOXYCARBONYL-(2R,3S)-(-)-6-OXO-2,3-DIPHENYL-4-MORPHOLINE
  • N-BOC(2R, 3S)-(-)-6-OXO-2,3-DIPHENYL-4-MORPHOLINE CARBOXYLATE
  • tert-butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morph
  • TERT-BUTYL (2R,3S)-(-)-6-OXO-2,3-DIPHENY L-4-MORPHOLINECARBOXYLATE, 99% (99% EE)
  • (2R,3S)-6-Oxo-2,3-diphenyl-morpholine-4-carboxylic acid tert-butyl ester
  • (2R,3S)-Tert-butyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate
  • (5S,6R)-N-BoC-5,6-diphenyl-2-morpholinone
  • (2R,3S)-tert-butyl (2R,3S)-6-oxo-2,3-diphenylmorpholine-4-carboxylate
  • (2R,3S)-6-Oxo-2,3-diphenyl-4-morpholinecarboxylic Acid 1,1-Dimethylethyl Ester
  • 4-Morpholinecarboxylicacid, 6-oxo-2,3-diphenyl-, 1,1-dimethylethyl ester, (2R,3S)-
  • (2R,3S)-6-Oxo-2,3-diphenyl-4-morpholinecarboxylic Acid tert-Butyl Ester,99%e.e.
  • (2R,3S)-(-)-N-Boc-6-oxo-2,3-diphenylMorpholine
  • (5R,6S)-(-)-4-Boc-5,6-diphenyl-2-Morpholinone, 98%
  • (2R,3S)-(-)-2,3-Diphenyl-6-oxomorpholine, N-BOC protected
  • tert-Butyl (2R,3S)-(-)-2,3-diphenyl-6-oxomorpholine-4-carboxylate
  • (2R,3S)-6-Oxo-2,3-diphenyl-4-morpholinecarboxylic Acid tert-Butyl Ester
  • (2<I>R</I>,3<I>S</I>)-(-)-<I>N</I>-Boc-6-oxo-2,3-diphenylMorpholine
  • 2-Oxo-7a-hydroxy Clopidogrel
  • (2R,3S)-6-Oxo-2,3-diphenyl-4-morpholinecarboxylic acid t-butyl ester, 98% (99% ee)
  • tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarbox
  • tert-butyl (2R,3S)-6-oxo-2,3-diphenylmorpholine-4-carboxylate
  • ert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
  • tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylic acid
  • 112741-49-8
  • Asymmetric Synthesis
  • Chiral Building Blocks
  • Heterocyclic Building Blocks
  • Morpholines
  • API intermediates
  • Chiral Building Blocks
  • Heterocyclic Building Blocks
  • Morpholines