ChemicalBook > CAS DataBase List > (S)-3-phenylmorpholine

(S)-3-phenylmorpholine

Product Name
(S)-3-phenylmorpholine
CAS No.
914299-79-9
Chemical Name
(S)-3-phenylmorpholine
Synonyms
(S)-3-phenylmorpholine;(S)-4-Phenylmorpholine;(3S)-3-phenylmorpholine;Morpholine, 3-phenyl-, (3S)-
CBNumber
CB91166254
Molecular Formula
C10H13NO
Formula Weight
163.22
MOL File
914299-79-9.mol
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(S)-3-phenylmorpholine Property

storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
Appearance
Off-white to light yellow Solid
optical activity
44.9069°(C=1.0038g/ml MEOH)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Synthonix
Product number
P61270
Product name
(S)-3-Phenylmorpholine
Purity
>98%
Packaging
100mg
Price
$25
Updated
2026/05/06
Synthonix
Product number
P61270
Product name
(S)-3-Phenylmorpholine
Purity
>98%
Packaging
250mg
Price
$30
Updated
2026/05/06
Synthonix
Product number
P61270
Product name
(S)-3-Phenylmorpholine
Purity
>98%
Packaging
1g
Price
$70
Updated
2026/05/06
Synthonix
Product number
P61270
Product name
(S)-3-Phenylmorpholine
Purity
>98%
Packaging
5g
Price
$280
Updated
2026/05/06
CHESS
Product number
3335-005
Product name
(S)-3-Phenyl-morpholine
Purity
>98
Packaging
5g
Price
$264
Updated
2026/05/25
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(S)-3-phenylmorpholine Chemical Properties,Usage,Production

Synthesis

1052209-96-7

914299-79-9

Step 3. A THF solution of (S)-5-phenylmorpholin-3-one (481 mg, dissolved in 6 mL of THF) was slowly added dropwise to a LiAlH4/THF suspension (0.47 g LiAlH4 dissolved in 2 mL of THF) at room temperature for a controlled time of over 5 minutes. After the dropwise addition, the reaction mixture was stirred at room temperature for 1 h, followed by transferring to a 72 °C oil bath for heating overnight. Upon completion of the reaction, the mixture was cooled to 0 °C and the reaction was quenched by sequential addition of H2O (0.47 mL), 3M NaOH aqueous solution (0.47 mL) and H2O (1.4 mL). The quenched mixture was diluted with Et2O (30 mL) and stirred for 10 min before separating the ether phase by filtration. The filtrate was concentrated and further dried under vacuum to give (S)-3-phenylmorpholine as a colorless solid (424 mg, 96% yield).LCMS (m/z): 164.2 (MH+), retention time 0.33 min.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 15, p. 4316 - 4320
[2] Angewandte Chemie - International Edition, 2013, vol. 52, # 20, p. 5319 - 5322
[3] Angew. Chem., 2013, vol. 125, # 20, p. 5427 - 5430,4
[4] Patent: US9242996, 2016, B2. Location in patent: Page/Page column 265; 266
[5] Patent: WO2018/116285, 2018, A1. Location in patent: Page/Page column 24

(S)-3-phenylmorpholine Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-3-phenylmorpholine Suppliers

Canada 1 China 70 India 1 United States 2 Global 74
ForeChem (Nantong) Technology Co.,Ltd.
Tel
513-85982855 18921614129
Fax
051385915507
Email
sales@xianxingpharm.com
Country
China
ProdList
2722
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61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Shanghai Longsheng chemical Co.,Ltd.
Tel
58099637 13585536065
Fax
021-58099609
Email
sales@shlschem.com
Country
China
ProdList
9894
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59
Shanghai Cuisen Pharmaceutical Technology Co., Ltd.
Tel
13472757003
Fax
+86 21 64968087
Email
yongnan.wang@cendrix.cn
Country
China
ProdList
962
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65
Shijiazhuang Lickon PharmaTech Co., Ltd.
Tel
031185291771 13832391721
Fax
0311-67305698
Email
yaofeng2005@163.com
Country
China
ProdList
967
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58
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
40000
Advantage
60
Chengdu Firster Pharmaceutical Co., Ltd.
Tel
028-87078428 028-87074958
Fax
8772-8116
Email
chengzhenyong@cdfirster.com
Country
China
ProdList
2580
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60
Shanghai Balmxy Pharmaceutical Co., Ltd
Tel
021-24206007 13764915196
Fax
86-021-23027023
Email
sales@balmxy.com
Country
China
ProdList
6923
Advantage
55
LABTER PHARMATECH(BEIJING) CO.,LTD
Tel
010-56330744 18310155299
Fax
010-56330744
Email
sales@labter.com.cn
Country
China
ProdList
20000
Advantage
55
AN PharmaTech Co Ltd
Tel
86(21)68097365
Fax
86(21)33321566
Email
sales@anpharma.net
Country
China
ProdList
4891
Advantage
55
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View Lastest Price from (S)-3-phenylmorpholine manufacturers

Career Henan Chemical Co
Product
(S)-3-phenylmorpholine 914299-79-9
Price
US $5.00/KG
Min. Order
1KG
Purity
95%-98%
Supply Ability
100kg
Release date
2019-09-03

914299-79-9, (S)-3-phenylmorpholineRelated Search:

3S-3-METHYLMORPHOLINE (S)-3-(tert-butyl)morpholine (R)-3-BENZYLMORPHOLINE (R)-3-ISOPROPYLMORPHOLINE, (S)-3-((S)-sec-butyl)Morpholine (R)-3-(tert-butyl)morpholine (R)-3-Methylmorpholine (S)-3-Isopropylmorpholine (R)-3-((R)-sec-butyl)morpholine (R)-3-Isobutylmorpholine tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Benzyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate (5S)-N-(tert-Butoxycarbonyl)-3,4,5,6-tetrahydro-5-phenyl-4(H)-1,4-oxazin-2-one (5R)-3,4,5,6-Tetrahydro-5-phenyl-4(H)-1,4-oxazin-2-one Aprepitant Fosaprepitant (5S)-3,4,5,6-TETRAHYDRO-5-PHENYL-N-(BENZYLOXYCARBONYL)-4(H)-1,4-OXAZIN-2-ONE (2R,6R,8S,12S)-1-AZA-10-OXA-12-PHENYLTRICYCLO[6.4.01,8.02,6]DODECAN-9-ONE

  • (S)-3-phenylmorpholine
  • Morpholine, 3-phenyl-, (3S)-
  • (3S)-3-phenylmorpholine
  • (S)-4-Phenylmorpholine
  • 914299-79-9