ANTI-PKC-DELTA

ANTI-PKC-DELTA Property

storage temp. 

-20°C

form 

buffered aqueous solution

biological source

rabbit

Safety

Storage Class

10 - Combustible liquids

Hazard and Precautionary Statements (GHS)

ANTI-PKC-DELTA Chemical Properties,Usage,Production

Uses

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. (provided by RefSeq)

Biological Activity

RIPK4 is a serine/threonine protein kinase th at interacts with protein kinase C-delta. The protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.