ChemicalBook > CAS DataBase List > 3alpha-Hydroxy-7-oxo-5beta-cholanic Acid
3alpha-Hydroxy-7-oxo-5beta-cholanic Acid
- Product Name
- 3alpha-Hydroxy-7-oxo-5beta-cholanic Acid
- CAS No.
- 4651-67-6
- Chemical Name
- 3alpha-Hydroxy-7-oxo-5beta-cholanic Acid
- Synonyms
- 7-KETOLITHOCHOLIC ACID;Nutriacholic acid;7-Oxolithocholic acid;3α-Hydroxy-7-oxo-5β-cholan-24-oic acid;3α-Hydroxy-7-ketocholanic acid;Chenodeoxycholic acid EP Impurity F;3ALPHA-HYDROXY-7-KETO-5BETA-CHOLANIC ACID;(R)-4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-Hydroxy-10,13-diMethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid;OCA-A;Nsc226118
- CBNumber
- CB2430908
- Molecular Formula
- C24H38O4
- Formula Weight
- 390.56
- MOL File
- 4651-67-6.mol
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3alpha-Hydroxy-7-oxo-5beta-cholanic Acid Property
- Melting point:
- 205°C
- Boiling point:
- 545.9±25.0 °C(Predicted)
- Density
- 1.124±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Dioxane (Slightly), DMSO (Slightly), Methanol (Slightly)
- pka
- 4.76±0.10(Predicted)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- 2.062mg/L at 25℃
- InChIKey
- DXOCDBGWDZAYRQ-QHVQYUNXNA-N
- SMILES
- C(O)(=O)CC[C@H]([C@@H]1[C@@]2(C)CC[C@]3([H])[C@@]4(C)CC[C@@H](O)C[C@@]4([H])CC(=O)[C@@]3([H])[C@]2([H])CC1)C |&1:5,6,7,11,13,17,20,25,27,r|
- LogP
- 3.48 at 20℃
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Safety
- Safety Statements
- 22-24/25
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 29546
- Product name
- 7-keto Lithocholic Acid
- Packaging
- 1g
- Price
- $84
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 29546
- Product name
- 7-keto Lithocholic Acid
- Packaging
- 10g
- Price
- $680
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 29546
- Product name
- 7-keto Lithocholic Acid
- Packaging
- 500mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 29546
- Product name
- 7-keto Lithocholic Acid
- Packaging
- 5g
- Price
- $384
- Updated
- 2024/03/01
Medical Isotopes, Inc.
- Product number
- 71777
- Product name
- NutriacholicAcid
- Packaging
- 1g
- Price
- $650
- Updated
- 2021/12/16
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3alpha-Hydroxy-7-oxo-5beta-cholanic Acid Chemical Properties,Usage,Production
Uses
Nutriacholic Acid (Ursodeoxycholic Acid EP Impurity F) is derivative of Lithocholic Acid (L469180), a cholic acid derivative as TGR5 modulator.
Uses
3alpha-Hydroxy-7-oxo-5beta-cholanic Acid is an intermediate in organic synthesis and pharmaceutical research and development. It can be used to synthesize the choleretic drug Obeticholic acid. Obeticholic acid can inhibit cholic acid synthesis. It is commonly used to treat primary biliary cirrhosis and nonalcoholic fatty liver disease.
Definition
ChEBI: 7-oxolithocholic acid is a bile acid that is lithocholic acid carrying an additional oxo substituent at position 7. It has a role as a human metabolite. It is a bile acid, a monohydroxy-5beta-cholanic acid, an oxo-5beta-cholanic acid and a 3alpha-hydroxy steroid. It is functionally related to a lithocholic acid. It is a conjugate acid of a 7-oxolithocholate.
Flammability and Explosibility
Non flammable
3alpha-Hydroxy-7-oxo-5beta-cholanic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
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3alpha-Hydroxy-7-oxo-5beta-cholanic Acid Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23680
- Advantage
- 75
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View Lastest Price from 3alpha-Hydroxy-7-oxo-5beta-cholanic Acid manufacturers
Shaanxi Dideu Medichem Co. Ltd
- Product
- 3-Hydroxy-7-oxocholan-24-oic acid 4651-67-6
- Price
- US $1.00-1.00/Kg/Bag
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 50tons
- Release date
- 2020-04-30
Wuhan Han Sheng New Material Technology Co.，Ltd
- Product
- 3alpha-Hydroxy-7-oxo-5beta-cholanic Acid 4651-67-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 50tons
- Release date
- 2023-08-25
XuZhou Magic Biotechnology Co., Ltd.
- Product
- 3ALPHA-HYDROXY-7-OXO-5BETA-CHOLANICACID 4651-67-6
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 96%
- Supply Ability
- 20tons
- Release date
- 2022-12-07
4651-67-6, 3alpha-Hydroxy-7-oxo-5beta-cholanic AcidRelated Search:
7-ketolithocholic Methyl ester
Cholan-24-oic acid, 7-hydrazono-3,12-dihydroxy-, (3α,5β,12α)-
(3α,5β,12α)-(3′α,5′β,12′α)-7,7′-(1,2-Hydrazinediylidene)bis[3,12-dihydroxycholan-24-oic acid]
7-KETODEOXYCHOLIC ACID
4-[(5S,7S,8S,10S,13R,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
(+)-NEOMENTHOL
(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
(2S)-2-[[[(1,1-Dimethylethyl)diphenylsilyl]oxy]methyl]-1,3-oxathiolan-5-ol 5-Acetate
Emtricitabine Impurity 18
Emtricitabine Impurity
5-fluoro-1-(2-(hydroxymethyl)-1,3-dioxolan-4-yl)cytosine
5-epi EMtricitabine
Ursodeoxycholic acid
2,4(1H,3H)-Pyrimidinedione,5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2S-cis)- (9CI)
Emtricitabine
Emtricitabine Impurity 8
ISOPULEGOL, TECH.
156198-94-6