Erythromycin stearate
- Product Name
- Erythromycin stearate
- CAS No.
- 643-22-1
- Chemical Name
- Erythromycin stearate
- Synonyms
- erypar;pfizer-e;gallimycin;bristamycin;oe7;Wemid;Ethryn;ethril;Eryprim;eratrex
- CBNumber
- CB2436793
- Molecular Formula
- C55H103NO15
- Formula Weight
- 1018.42
- MOL File
- 643-22-1.mol
Erythromycin stearate Property
- Melting point:
- 77-79°C
- storage temp.
- 2-8°C
- solubility
- ethanol: soluble50mg/mL, clear to very slightly hazy, colorless
- color
- white to off-white
- Stability:
- Stable. Combustible. Incompatible with acids, strong oxidizing agents.
- EPA Substance Registry System
- Erythromycin stearate (643-22-1)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 42/43-36/37/38
- Safety Statements
- 36-26
- WGK Germany
- 2
- RTECS
- KF5785000
- HS Code
- 29415000
- Hazardous Substances Data
- 643-22-1(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284Wear respiratory protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- E1500800
- Product name
- Erythromycin stearate
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- e1500800
- Price
- $153
- Updated
- 2024/03/01
- Product number
- BP488
- Product name
- Erythromycin stearate
- Purity
- British Pharmacopoeia (BP) Reference Standard
- Packaging
- 100MG
- Price
- $267
- Updated
- 2024/03/01
- Product number
- 1248006
- Product name
- Erythromycin stearate
- Packaging
- 200mg
- Price
- $198
- Updated
- 2024/03/01
- Product number
- E3454-05
- Product name
- Erythromycin Stearate
- Packaging
- 10g
- Price
- $297
- Updated
- 2021/12/16
- Product number
- 257298
- Product name
- Erythromycin stearate
- Packaging
- 50g
- Price
- $307
- Updated
- 2021/12/16
Erythromycin stearate Chemical Properties,Usage,Production
Chemical Properties
White Solid
Originator
Erythrocin Stearate,Abbott,US,1952
Uses
Semi-synthetic macrolide antibiotic. Antibacterial
Uses
oil lubricant, plasticizer, solvent
Uses
Macrodiles antibacterial
Definition
ChEBI: Erythromycin stearate is an aminoglycoside.
Manufacturing Process
To a well-stirred solution of 3.18 grams (10.5 mmol) of stearoyl chloride and 1.24 grams (11.0 mmol) of 1-ethylpiperidine in 50 ml of methylene chloride is added 7.20 grams (10.0 mmol) of erythromycin. After a short time complete solution is obtained and stirring is then discontinued. The solution is allowed to stand overnight. The solution is diluted to 250 ml by the addition of methylene chloride and washed three times with 100 ml portions of water followed by two washes with 5% sodium bicarbonate solution. The organic layer is dried over anhydrous sodium sulfate and filtered, the solvent being removed under diminished pressure. The product is dried to constant weightat room temperature in a vacuum desiccator.
brand name
Bristamycin (Bristol-Myers Squibb); Erythrocin (Abbott).
Therapeutic Function
Antibacterial
General Description
Erythromycin stearate (Ethril, Wyamycin S, Erypar) is thestearic acid salt of erythromycin. Like erythromycin base,the stearate is acid labile. It is film coated to protect it fromacid degradation in the stomach. In the alkaline pH of theduodenum, the free base is liberated from the stearateand absorbed. Erythromycin stearate is a crystalline powderthat is practically insoluble in water but soluble in alcoholand ether.
General Description
Fluffy colorless powder or fine white powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
A base. Readily forms salts with acids.
Fire Hazard
Flash point data for Erythromycin stearate are not available; however, Erythromycin stearate is probably combustible.
Erythromycin stearate Preparation Products And Raw materials
Raw materials
Preparation Products
Erythromycin stearate Suppliers
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View Lastest Price from Erythromycin stearate manufacturers
- Product
- Erythromycin stearate 643-22-1
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2021-09-01
- Product
- Erythromycin stearate 643-22-1
- Price
- US $1.00-1.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 50tons
- Release date
- 2020-05-07
- Product
- Erythromycin stearate 643-22-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-08-31