2-(Trifluoromethyl)benzyl alcohol
- Product Name
- 2-(Trifluoromethyl)benzyl alcohol
- CAS No.
- 346-06-5
- Chemical Name
- 2-(Trifluoromethyl)benzyl alcohol
- Synonyms
- OTF-BYL;RARECHEM AL BD 0046;2-TRIFLUOROBENZYL ALCOHOL;o-Trifluoromethylbenzyl alchol;2-Hydroxymethylbenzotrifluoride;2-(TRIFLUOROMETHYL)BENZYL ALCOHOL;O-(TRIFLUOROMETHYL)BENZYL ALCOHOL;2-TRIFLUOROMETHYL BENZENE METHANOL;[2-(TRIFLUOROMETHYL)PHENYL]METHANOL;2-(Trifluoromethyl)benzylalcohol97%
- CBNumber
- CB2443003
- Molecular Formula
- C8H7F3O
- Formula Weight
- 176.14
- MOL File
- 346-06-5.mol
2-(Trifluoromethyl)benzyl alcohol Property
- Melting point:
- 4°C
- Boiling point:
- 90 °C20 mm Hg(lit.)
- Density
- 1.326 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.468(lit.)
- Flash point:
- 198 °F
- storage temp.
- Sealed in dry,Room Temperature
- form
- clear liquid
- pka
- 14.01±0.10(Predicted)
- color
- Colorless to Almost colorless
- BRN
- 2093714
- CAS DataBase Reference
- 346-06-5(CAS DataBase Reference)
- NIST Chemistry Reference
- 2-(Trifluoromethyl)benzyl alcohol(346-06-5)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39-37/39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29062990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 233102
- Product name
- 2-(Trifluoromethyl)benzyl alcohol
- Purity
- 97%
- Packaging
- 5g
- Price
- $33.6
- Updated
- 2022/05/15
- Product number
- T1311
- Product name
- 2-(Trifluoromethyl)benzyl Alcohol
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $40
- Updated
- 2025/07/31
- Product number
- T797015
- Product name
- 2-(Trifluoromethyl)benzyl Alcohol
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- T797015
- Product name
- 2-(Trifluoromethyl)benzyl Alcohol
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 005510
- Product name
- 2-(Trifluoromethyl)benzyl alcohol
- Purity
- 97%
- Packaging
- 100g
- Price
- $79
- Updated
- 2021/12/16
2-(Trifluoromethyl)benzyl alcohol Chemical Properties,Usage,Production
Chemical Properties
Colorless to light yellow liqui
Uses
2-(Trifluoromethyl)benzyl alcohol has been used to investigate the aromatic aldehydes as substrate for yeast alcohol dehydrogenase.
Definition
ChEBI: [2-(Trifluoromethyl)phenyl]methanol is a member of (trifluoromethyl)benzenes.
Synthesis
447-61-0
346-06-5
(1) Water (348.0 g) was added to a 1000 mL three-necked round-bottomed flask equipped with a mechanical stirrer and a thermometer and cooled to 0°C. Subsequently, sodium borohydride (9.5 g, 0.25 mol) was added and stirred for 20 min. Maintaining the temperature at 5 °C, o-trifluoromethylbenzaldehyde (87.1 g, 0.5 mol) was slowly added dropwise. After the dropwise addition, the reaction temperature was maintained at 10 °C for 1 hour. After completion of the reaction, extraction was carried out by adding methyl tert-butyl ether. The organic phases were combined, washed with saturated brine and concentrated under reduced pressure to no fraction to obtain 2-trifluoromethylbenzenemethanol as a colorless transparent liquid with a purity of >99% and a yield of 90%.
References
[1] Patent: CN106588673, 2017, A. Location in patent: Paragraph 0047; 0048
[2] Patent: CN106699729, 2017, A. Location in patent: Paragraph 0066; 0067
[3] Green Chemistry, 2015, vol. 17, # 9, p. 4537 - 4540
[4] Journal of Organic Chemistry, 2017, vol. 82, # 13, p. 6972 - 6977
2-(Trifluoromethyl)benzyl alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
2-(Trifluoromethyl)benzyl alcohol Suppliers
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- Country
- Italy
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View Lastest Price from 2-(Trifluoromethyl)benzyl alcohol manufacturers
- Product
- 2-(Trifluoromethyl)benzyl alcohol 346-06-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20t
- Release date
- 2024-06-11
- Product
- 2-(Trifluoromethyl)benzyl alcohol 346-06-5
- Price
- US $130.00/KG
- Min. Order
- 1KG
- Purity
- 99
- Supply Ability
- 10000KG
- Release date
- 2020-11-09
- Product
- 2-(Trifluoromethyl)benzyl alcohol 346-06-5
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- as request
- Release date
- 2018-12-21