H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH
- Product Name
- H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH
- CAS No.
- 144796-71-4
- Chemical Name
- H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH
- Synonyms
- TNF-a(31-45);RRANALLANGVELRD;TNF-α (31-45), human;TNF-A (31-45) (HUMAN);TNF - α (31 - 45), human;TNF-ALPHA (31-45) (HUMAN);TNF - ALFA (31 - 45), HUMAN;TNF-Alpha (31-45) (human) CAS 144796-71-4;TUMOR NECROSIS FACTOR-ALPHA (31-45) (HUMAN);tumor necrosis factor-α human fragment 31-45
- CBNumber
- CB2450858
- Molecular Formula
- C69H122N26O22
- Formula Weight
- 1667.87
- MOL File
- 144796-71-4.mol
H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH Property
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- Soluble in DMSO
- pka
- 2.86±0.10(Predicted)
- form
- Solid
- color
- White to off-white
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- CYT0000061
- Product name
- TUMOR NECROSIS FACTOR-ALPHA FRAGMENT31-45-HUMAN
- Purity
- 95.00%
- Packaging
- 0.1MG
- Price
- $656.62
- Updated
- 2021/12/16
H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH Chemical Properties,Usage,Production
Uses
TNF-α (31-45), human is a potent NF-kB pathway activator. TNF-αis a proinflammatory cytokine that induces necrosis or apoptosis. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis[1][2][3].
IC 50
NF-κB
References
[1] Idriss HT, Naismith JH. TNF alpha and the TNF receptor superfamily: structure-function relationship(s). Microsc Res Tech. 2000 Aug 1;50(3):184-95. DOI:10.3390/ijms22052719
[2] Xi Rui, et al. RPS3 Promotes the Metastasis and Cisplatin Resistance of Adenoid Cystic Carcinoma. Front Oncol. 2022 Jun 30:12:804439. DOI:10.3389/fonc.2022.804439
[3] Jang DI, et al. The Role of Tumor Necrosis Factor Alpha (TNF-α) in Autoimmune Disease and Current TNF-α Inhibitors in Therapeutics. Int J Mol Sci. 2021 Mar 8;22(5):2719. DOI:10.3390/ijms22052719
H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH Preparation Products And Raw materials
Raw materials
Preparation Products
H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH Suppliers
- Tel
- 21-61263452 13641803416
- Fax
- 86-21-61263399
- ymbetter@glbiochem.com
- Country
- China
- ProdList
- 9981
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 15402
- Advantage
- 60
- Tel
- 0551-65326643 18156095617
- Fax
- 0551-65326641
- info@cellmano.com
- Country
- China
- ProdList
- 1010
- Advantage
- 55
- Tel
- 17705183659
- Fax
- 84523390
- sales@njleonbiotech.com
- Country
- China
- ProdList
- 5501
- Advantage
- 55
- Tel
- 025-58361106-805 15951641583
- Fax
- 025-58361106-806
- zhao.xu@njpeptide.com
- Country
- China
- ProdList
- 9979
- Advantage
- 55
- Tel
- +86-17380623303
- Fax
- 028-62328193
- Caroline@youngshechem.com
- Country
- China
- ProdList
- 4802
- Advantage
- 58
- Tel
- 0571-87213919
- Eric@peptidego.com
- Country
- China
- ProdList
- 7408
- Advantage
- 58
- Tel
- meitaochem@126.com
- meitaochem@126.com
- Country
- China
- ProdList
- 19103
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
View Lastest Price from H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH manufacturers
- Product
- CB2450858 144796-71-4
- Price
- US $17.00/mg
- Min. Order
- 25mg
- Purity
- 95%
- Supply Ability
- 1KG
- Release date
- 2020-10-27