ChemicalBook > CAS DataBase List > H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH

H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH

Product Name
H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH
CAS No.
144796-71-4
Chemical Name
H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH
Synonyms
TNF-a(31-45);RRANALLANGVELRD;TNF-α (31-45), human;TNF-A (31-45) (HUMAN);TNF - α (31 - 45), human;TNF-ALPHA (31-45) (HUMAN);TNF - ALFA (31 - 45), HUMAN;TNF-Alpha (31-45) (human) CAS 144796-71-4;TUMOR NECROSIS FACTOR-ALPHA (31-45) (HUMAN);tumor necrosis factor-α human fragment 31-45
CBNumber
CB2450858
Molecular Formula
C69H122N26O22
Formula Weight
1667.87
MOL File
144796-71-4.mol
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H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH Property

Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Soluble in DMSO
pka
2.86±0.10(Predicted)
form 
Solid
color 
White to off-white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CYT0000061
Product name
TUMOR NECROSIS FACTOR-ALPHA FRAGMENT31-45-HUMAN
Purity
95.00%
Packaging
0.1MG
Price
$656.62
Updated
2021/12/16
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H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH Chemical Properties,Usage,Production

Uses

TNF-α (31-45), human is a potent NF-kB pathway activator. TNF-αis a proinflammatory cytokine that induces necrosis or apoptosis. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis[1][2][3].

IC 50

NF-κB

References

[1] Idriss HT, Naismith JH. TNF alpha and the TNF receptor superfamily: structure-function relationship(s). Microsc Res Tech. 2000 Aug 1;50(3):184-95. DOI:10.3390/ijms22052719
[2] Xi Rui, et al. RPS3 Promotes the Metastasis and Cisplatin Resistance of Adenoid Cystic Carcinoma. Front Oncol. 2022 Jun 30:12:804439. DOI:10.3389/fonc.2022.804439
[3] Jang DI, et al. The Role of Tumor Necrosis Factor Alpha (TNF-α) in Autoimmune Disease and Current TNF-α Inhibitors in Therapeutics. Int J Mol Sci. 2021 Mar 8;22(5):2719. DOI:10.3390/ijms22052719

H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH manufacturers

Career Henan Chemica Co
Product
CB2450858 144796-71-4
Price
US $17.00/mg
Min. Order
25mg
Purity
95%
Supply Ability
1KG
Release date
2020-10-27

144796-71-4, H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OHRelated Search:


  • RRANALLANGVELRD
  • TUMOR NECROSIS FACTOR-ALPHA FRAGMENT 31-45 HUMAN
  • TUMOR NECROSIS FACTOR-ALPHA (31-45) (HUMAN)
  • TNF-A (31-45) (HUMAN)
  • TNF-ALPHA (31-45) (HUMAN)
  • ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP
  • H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH
  • tumor necrosis factor-α human fragment 31-45
  • TNF - α (31 - 45), human
  • TuMor Necrosis Factor-alpha HuMan FragMent 31-45
  • TNF - ALFA (31 - 45), HUMAN
  • L-Aspartic acid, L-arginyl-L-arginyl-L-alanyl-L-asparaginyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-asparaginylglycyl-L-valyl-L-α-glutamyl-L-leucyl-L-arginyl- (9CI)
  • TNF-α (31-45), human
  • L-Aspartic acid,L-arginyl-L-arginyl-L-alanyl-L-asparaginyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-asparaginylglycyl-L-valyl-L-α-glutamyl-L-leucyl-L-arginyl-
  • TNF-Alpha (31-45) (human) CAS 144796-71-4
  • TNF-a(31-45)
  • 144796-71-4
  • C69H122N26O22
  • Other Peptides
  • Peptides
  • Amino Acids and Peptides
  • BioChemical
  • Biochemicals and Reagents
  • peptide