H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH
- Product Name
- H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH
- CAS No.
- 144796-71-4
- Chemical Name
- H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH
- Synonyms
- TNF-a(31-45);RRANALLANGVELRD;TNF-α (31-45), human;TNF-A (31-45) (HUMAN);TNF - α (31 - 45), human;TNF-ALPHA (31-45) (HUMAN);TNF - ALFA (31 - 45), HUMAN;TNF-Alpha (31-45) (human) CAS 144796-71-4;TUMOR NECROSIS FACTOR-ALPHA (31-45) (HUMAN);tumor necrosis factor-α human fragment 31-45
- CBNumber
- CB2450858
- Molecular Formula
- C69H122N26O22
- Formula Weight
- 1667.87
- MOL File
- 144796-71-4.mol
H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH Property
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- Soluble in DMSO
- pka
- 2.86±0.10(Predicted)
- form
- Solid
- color
- White to off-white
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- CYT0000061
- Product name
- TUMOR NECROSIS FACTOR-ALPHA FRAGMENT31-45-HUMAN
- Purity
- 95.00%
- Packaging
- 0.1MG
- Price
- $656.62
- Updated
- 2021/12/16
H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH Chemical Properties,Usage,Production
Uses
TNF-α (31-45), human is a potent NF-kB pathway activator. TNF-αis a proinflammatory cytokine that induces necrosis or apoptosis. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis[1][2][3].
IC 50
NF-κB
References
[1] Idriss HT, Naismith JH. TNF alpha and the TNF receptor superfamily: structure-function relationship(s). Microsc Res Tech. 2000 Aug 1;50(3):184-95. DOI:10.3390/ijms22052719
[2] Xi Rui, et al. RPS3 Promotes the Metastasis and Cisplatin Resistance of Adenoid Cystic Carcinoma. Front Oncol. 2022 Jun 30:12:804439. DOI:10.3389/fonc.2022.804439
[3] Jang DI, et al. The Role of Tumor Necrosis Factor Alpha (TNF-α) in Autoimmune Disease and Current TNF-α Inhibitors in Therapeutics. Int J Mol Sci. 2021 Mar 8;22(5):2719. DOI:10.3390/ijms22052719
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View Lastest Price from H-ARG-ARG-ALA-ASN-ALA-LEU-LEU-ALA-ASN-GLY-VAL-GLU-LEU-ARG-ASP-OH manufacturers
- Product
- CB2450858 144796-71-4
- Price
- US $17.00/mg
- Min. Order
- 25mg
- Purity
- 95%
- Supply Ability
- 1KG
- Release date
- 2020-10-27