GAMMA-LINOLENIC ACID METHYL ESTER
- Product Name
- GAMMA-LINOLENIC ACID METHYL ESTER
- CAS No.
- 16326-32-2
- Chemical Name
- GAMMA-LINOLENIC ACID METHYL ESTER
- Synonyms
- METHYL GLA;LIGAMO-007;(6Z,9Z,12Z);FAME 18:3N-6;METHYLG-LINOLENATE;Methyl y-linolenate;METHYL-GAMA-LINOLENATE;METHYL GAMMA-LINOLENATE;Caprylic Acid Impurity 72;Methyl γ-linolenate(C18:3)
- CBNumber
- CB2454755
- Molecular Formula
- C19H32O2
- Formula Weight
- 292.46
- MOL File
- 16326-32-2.mol
GAMMA-LINOLENIC ACID METHYL ESTER Property
- Boiling point:
- 162 °C0.5 mm Hg(lit.)
- Density
- 0.9019 g/cm3
- refractive index
- n20/D 1.476(lit.)
- Flash point:
- 62 °C
- storage temp.
- -20°C
- solubility
- ≤100mg/ml in DMSO;100mg/ml in dimethyl formamide
- form
- Liquid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P235Store in a well-ventilated place. Keep cool.
N-Bromosuccinimide Price
- Product number
- L6503
- Product name
- Methyl γ-linolenate
- Purity
- ≥99% (GC)
- Packaging
- 1g
- Price
- $644
- Updated
- 2024/03/01
- Product number
- 00238
- Product name
- Methyl γ-linolenate solution
- Purity
- analytical standard
- Packaging
- 1mL
- Price
- $629
- Updated
- 2022/05/15
- Product number
- 10006579
- Product name
- γ-Linolenic Acid methyl ester
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 10006579
- Product name
- γ-Linolenic Acid methyl ester
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $61
- Updated
- 2024/03/01
- Product number
- L6503
- Product name
- Methyl γ-linolenate
- Purity
- ≥99% (GC)
- Packaging
- 100mg
- Price
- $119
- Updated
- 2024/03/01
GAMMA-LINOLENIC ACID METHYL ESTER Chemical Properties,Usage,Production
Description
Polyunsaturated fatty acids (PUFAs) are essential nutrients that show distinct deficiency syndromes when not present in adequate amounts in the diet. γ-
Uses
Methyl γ-linolenate may be used as an analytical standard for the determination of aldehydes such as pentanal and hexanal via peroxidation, further analyzed by gas chromatography technique. It may also be used as an analytical reference standard for the quantification of the analyte in serum lipid extract and Arthrospira (Spirulina) platensis using the gas-chromatography technique.
Definition
ChEBI: Methyl gamma-linolenate is a fatty acid methyl ester obtained from the formal condensation of methanol and gamma-linolenic acid. It has a role as a bacterial metabolite, an apoptosis inducer, an antineoplastic agent and an antibacterial agent. It is functionally related to a gamma-linolenic acid.
Biochem/physiol Actions
Methyl γ-linolenate (C18:6,9,12) differs from methyl α-linolenate (C18:9,12,15) in the positions of the double bonds. Methyl γ-linolenate may be used in nutritional studies regarding weight regain and as a possible tumor suppression agent.
in vitro
γ-linolenic acid methyl ester is an esterified version of the free acid which is less water soluble but more amenable for the formulation of gla-containing diets and dietary supplements. gla was identified as an ω-6 fatty acid which could be elongated to arachidonic acid for endogenous eicosanoid synthesis. gla was found to be a weak leukotriene b4 (ltb4) receptor antagonist, which was able to inhibit [3h]-ltb4 binding to porcine neutrophil membranes with a ki of 1 μm [1].
in vivo
in an in-vivo model of ltb4-induced bronchoconstriction, ricinelaidic acid andγ-linolenic acid methyl ester at a 1 mg/kg i.v. dose could result in 46% and 53% inhibition, respectively, indicating that essential fatty acids are ltb4 receptor antagonists, which may account in part for their reported anti-inflammatory activities [1].
References
[1] yagaloff, k. a.,franco, l.,simko, b., et al. essential fatty acids are antagonists of the leukotriene b4 receptor. prostaglandins, leukotrienes and essential fatty acids 52, 293-297 (1995).
GAMMA-LINOLENIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
GAMMA-LINOLENIC ACID METHYL ESTER Suppliers
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15848
- Advantage
- 69
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- zhangsn@titansci.com
- Country
- China
- ProdList
- 14113
- Advantage
- 59
- Tel
- 021-54306202 13764082696;
- info@hanhongsci.com
- Country
- China
- ProdList
- 42982
- Advantage
- 64
- Tel
- 13355009207 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18739
- Advantage
- 57
- Tel
- 400-1166-196 18981987031
- Fax
- 028-84555506 800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 11726
- Advantage
- 57
- Tel
- 4008-755-333 18080918076
- Fax
- 028-86757656
- 800078821@qq.com
- Country
- China
- ProdList
- 9725
- Advantage
- 55
- Tel
- 400-6206333 18521732826;
- Fax
- 021-50323701
- market@aladdin-e.com
- Country
- China
- ProdList
- 25015
- Advantage
- 65
- Tel
- 021-33632979 15002134094
- Fax
- 021-33632979
- marketing@targetmol.com
- Country
- China
- ProdList
- 7934
- Advantage
- 58
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- 422131432@qq.com
- Country
- China
- ProdList
- 9986
- Advantage
- 55
View Lastest Price from GAMMA-LINOLENIC ACID METHYL ESTER manufacturers
- Product
- GAMMA-LINOLENIC ACID METHYL ESTER 16326-32-2
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-05-24