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γ-Linolenic Acid Ethyl Ester

Product Name
γ-Linolenic Acid Ethyl Ester
CAS No.
31450-14-3
Chemical Name
γ-Linolenic Acid Ethyl Ester
Synonyms
Ethyl linolenate gamma;Ethyl gamma-linolenate;Ethyl gamma-linolenic acid;GAMMA-LINOLENIC ACID ETHYL ESTER;Ethyl Gamma-Linolenic Acid(C18:3);Gamma Linolenic Acid Ethyl Ester (90%);Ethyl 6(Z),9(Z),12(Z)-octadecatrienoate;6,9,12-OCTADECATRIENOIC ACID ETHYL ESTER;Gamma Linolenic acid ethyl ester (GLA-EE);Ethyl linolenate gamma@10 mg/mL in Hexane
CBNumber
CB5229451
Molecular Formula
C20H34O2
Formula Weight
306.48
MOL File
31450-14-3.mol
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γ-Linolenic Acid Ethyl Ester Property

Boiling point:
390.6±31.0 °C(Predicted)
Density 
0.893±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
liquid
color 
Colourless
Stability:
Light Sensitive
InChI
InChI=1S/C20H34O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22-4-2/h8-9,11-12,14-15H,3-7,10,13,16-19H2,1-2H3/b9-8-,12-11-,15-14-
InChIKey
MJLYTDAIYLGSRZ-ORZIMQNZSA-N
SMILES
C(OCC)(=O)CCCC/C=C\C/C=C\C/C=C\CCCCC
LogP
7.562 (est)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
9000738
Product name
γ-Linolenic Acid ethyl ester
Purity
≥98%
Packaging
50mg
Price
$34
Updated
2024/03/01
Cayman Chemical
Product number
9000738
Product name
γ-Linolenic Acid ethyl ester
Purity
≥98%
Packaging
100mg
Price
$64
Updated
2024/03/01
Cayman Chemical
Product number
9000738
Product name
γ-Linolenic Acid ethyl ester
Purity
≥98%
Packaging
250mg
Price
$150
Updated
2024/03/01
Cayman Chemical
Product number
9000738
Product name
γ-Linolenic Acid ethyl ester
Purity
≥98%
Packaging
1g
Price
$395
Updated
2024/03/01
TRC
Product number
L467680
Product name
γ-LinolenicAcidEthylEster
Packaging
250mg
Price
$130
Updated
2021/12/16
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γ-Linolenic Acid Ethyl Ester Chemical Properties,Usage,Production

Description

γ-Linolenic acid (GLA) is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak leukotriene B4 (LTB4) receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki value of 1 μM. GLA produces 53% inhibition at a 1 mg/kg dose in an in vivo model of LTB4-induced bronchoconstriction. GLA ethyl ester is an esterified version of the free acid which is less water soluble but more amenable for the formulation of GLA-containing diets.

Uses

γ-Linolenic Acid Ethyl Ester is used in biological studies for neoplasm inhibition of cultured carcinoma cells of human breast. This analog is also used in the evaluation of hypocholesterolemic activity in rats by comparing it with γ-Linolenic Acid (L467660).

Definition

ChEBI: Gamma-Linolenic acid ethyl ester is a long-chain fatty acid ethyl ester.

Purification Methods

To highly purify γ-linolenic acid (GLA) from microbial lipids, various types of zeolites were investigated in a fixed-bed column system, where a two-step desoprtion operation mode was found to be superior in selective separation of GLA. By this system, GLA ethyl ester of 98 mol% purity was obtained from a mixture of various polysaturated and unsaturated fatty acid esters using cesium Y and methyl-, dimethyl- and ethylammonium Y zeolites[1].

References

[1] MAKOTO ARAI Hisashi M Hideki Fukuda. Selective separation of γ-linolenic acid ethyl ester using y-zeolite[J]. Journal of Fermentation Technology, 1987. DOI:10.1016/0385-6380(87)90118-X.

γ-Linolenic Acid Ethyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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γ-Linolenic Acid Ethyl Ester Suppliers

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Yichang Zhongyitai Trading Co., Ltd.
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0717-6449896 13886658719
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0717-6558598
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ChemStrong Scientific Co.,Ltd
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0755-0755-66853366 13670046396
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0755-28363542
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sales@chem-strong.com
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Alfa Chemistry
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1-516-6625404
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1-516-927-0118
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support@alfa-chemistry.com
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United States
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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021-65675885
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Beijing Solarbio Science & Tecnology Co., Ltd.
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010-50973130 4009686088
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China
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Beijing Jin Ming Biotechnology Co., Ltd.
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Shanghai Uteam Biotechnology Co., Ltd.
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021-36031160 13311776681
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China
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Shanghai Biological Technology Development Co., Ltd.
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021-69955236-807 13918189704
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021-65211385
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chinaruji@chinaruji.com
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China
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Shenzhen Regent Biochemical Technology Co., Ltd.
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0755-0755-85201366 18938635012
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0755-85201366
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sales@regentsciences.com
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View Lastest Price from γ-Linolenic Acid Ethyl Ester manufacturers

Career Henan Chemical Co
Product
GAMMA-LINOLENIC ACID ETHYL ESTER 31450-14-3
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-05-24

31450-14-3, γ-Linolenic Acid Ethyl EsterRelated Search:


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  • Ethyl Gamma-Linolenic Acid(C18:3)
  • (6Z,9Z,12Z)-ethyl octadeca-6,9,12-trienoate
  • Ethyl 6(Z),9(Z),12(Z)-octadecatrienoate
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  • 31450-14-3
  • Biochemicals and Reagents
  • BioChemical
  • Fatty Acids
  • Ethyl Ester
  • Esters
  • Lipids
  • Unsaturated fatty acids and derivatives