γ-Linolenic Acid Ethyl Ester

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γ-Linolenic Acid Ethyl Ester

Product Name: γ-Linolenic Acid Ethyl Ester
CAS No.: 31450-14-3
Chemical Name: γ-Linolenic Acid Ethyl Ester
Synonyms: Ethyl linolenate gamma;Ethyl gamma-linolenate;Ethyl gamma-linolenic acid;GAMMA-LINOLENIC ACID ETHYL ESTER;Ethyl Gamma-Linolenic Acid(C18:3);Gamma Linolenic Acid Ethyl Ester (90%);Ethyl 6(Z),9(Z),12(Z)-octadecatrienoate;6,9,12-OCTADECATRIENOIC ACID ETHYL ESTER;Gamma Linolenic acid ethyl ester (GLA-EE);Ethyl linolenate gamma@10 mg/mL in Hexane
CBNumber: CB5229451
Molecular Formula: C20H34O2
Formula Weight: 306.48
MOL File: 31450-14-3.mol

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γ-Linolenic Acid Ethyl Ester Property

Boiling point:: 390.6±31.0 °C(Predicted)
Density: 0.893±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
form: liquid
color: Colourless
Stability:: Light Sensitive
InChI: InChI=1S/C20H34O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22-4-2/h8-9,11-12,14-15H,3-7,10,13,16-19H2,1-2H3/b9-8-,12-11-,15-14-
InChIKey: MJLYTDAIYLGSRZ-ORZIMQNZSA-N
SMILES: C(OCC)(=O)CCCC/C=C\C/C=C\C/C=C\CCCCC
LogP: 7.562 (est)

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 9000738
Product name: γ-Linolenic Acid ethyl ester
Purity: ≥98%
Packaging: 50mg
Price: $34
Updated: 2024/03/01

Cayman Chemical

Product number: 9000738
Product name: γ-Linolenic Acid ethyl ester
Purity: ≥98%
Packaging: 100mg
Price: $64
Updated: 2024/03/01

Cayman Chemical

Product number: 9000738
Product name: γ-Linolenic Acid ethyl ester
Purity: ≥98%
Packaging: 250mg
Price: $150
Updated: 2024/03/01

Cayman Chemical

Product number: 9000738
Product name: γ-Linolenic Acid ethyl ester
Purity: ≥98%
Packaging: 1g
Price: $395
Updated: 2024/03/01

TRC

Product number: L467680
Product name: γ-LinolenicAcidEthylEster
Packaging: 250mg
Price: $130
Updated: 2021/12/16

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γ-Linolenic Acid Ethyl Ester Chemical Properties,Usage,Production

Description

γ-Linolenic acid (GLA) is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak leukotriene B₄ (LTB₄) receptor antagonist, inhibiting [³H]-LTB₄ binding to porcine neutrophil membranes with a K_i value of 1 μM. GLA produces 53% inhibition at a 1 mg/kg dose in an in vivo model of LTB₄-induced bronchoconstriction. GLA ethyl ester is an esterified version of the free acid which is less water soluble but more amenable for the formulation of GLA-containing diets.

Uses

γ-Linolenic Acid Ethyl Ester is used in biological studies for neoplasm inhibition of cultured carcinoma cells of human breast. This analog is also used in the evaluation of hypocholesterolemic activity in rats by comparing it with γ-Linolenic Acid (L467660).

Definition

ChEBI: Gamma-Linolenic acid ethyl ester is a long-chain fatty acid ethyl ester.

Purification Methods

To highly purify γ-linolenic acid (GLA) from microbial lipids, various types of zeolites were investigated in a fixed-bed column system, where a two-step desoprtion operation mode was found to be superior in selective separation of GLA. By this system, GLA ethyl ester of 98 mol% purity was obtained from a mixture of various polysaturated and unsaturated fatty acid esters using cesium Y and methyl-, dimethyl- and ethylammonium Y zeolites^[1].

References

[1] MAKOTO ARAI Hisashi M Hideki Fukuda. Selective separation of γ-linolenic acid ethyl ester using y-zeolite[J]. Journal of Fermentation Technology, 1987. DOI:10.1016/0385-6380(87)90118-X.

γ-Linolenic Acid Ethyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from γ-Linolenic Acid Ethyl Ester manufacturers

Career Henan Chemical Co

Product: GAMMA-LINOLENIC ACID ETHYL ESTER 31450-14-3
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2019-05-24

31450-14-3, γ-Linolenic Acid Ethyl EsterRelated Search:

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6,9,12-OCTADECATRIENOIC ACID ETHYL ESTER

GAMMA-LINOLENIC ACID ETHYL ESTER

DELTA 6 CIS 9 CIS 12 CIS OCTADECATRIENOIC ACID ETHYL ESTER

6,9,12-Octadecatrienoic acid, ethyl ester, (6Z,9Z,12Z)-

γ-Linolenic acid ethyl ester, 6,9,12-Octadecatrienoic acid ethyl ester

Ethyl linolenate gamma

(6Z,9Z,12Z)-6,9,12-Octadecatrienoic acid ethyl ester

Ethyl gamma-linolenate

Ethyl gamma-linolenic acid

Ethyl (6Z,9Z,12Z)-octadeca-6,9,12-trienoate

Gamma Linolenic Acid Ethyl Ester (90%)

Gamma Linolenic acid ethyl ester (GLA-EE)

Ethyl linolenate gamma@10 mg/mL in Hexane

cis-6,cis-9,cis-12 Octadecadienoic acid ethyl ester

Ethyl Gamma-Linolenic Acid(C18:3)

(6Z,9Z,12Z)-ethyl octadeca-6,9,12-trienoate

Ethyl 6(Z),9(Z),12(Z)-octadecatrienoate

Ethyl (6Z,9Z,12Z)-6,9,12- octadecatrienoic acid

All Cis 6-9-12 Octadecatrienoic Ethyl Ester

31450-14-3

Biochemicals and Reagents

BioChemical

Fatty Acids

Ethyl Ester

Esters

Lipids

Unsaturated fatty acids and derivatives