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ADRENIC ACID

Product Name
ADRENIC ACID
CAS No.
28874-58-0
Chemical Name
ADRENIC ACID
Synonyms
ADRENIC ACID;DOCOSATETRAENOIC ACID;Adrenic Acid (22:4, n-6);Ethyl Acetate Impurity 104;Adrenic Acid (Solution in ethanol);Adrenic acid(cis-7,10,13,16)(C22:4);7Z,10Z,13Z,16Z-DOCOSATETRAENOIC ACID;DOCOSA-7Z,10Z,13Z,16Z-TETRAENOIC ACID;DOCOSA-7Z,10Z,13Z,16Z-PENTAENOIC ACID;CIS-7,10,13,16-DOCOSA-TETRAENOIC ACID
CBNumber
CB2456229
Molecular Formula
C22H36O2
Formula Weight
332.52
MOL File
28874-58-0.mol
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ADRENIC ACID Property

Boiling point:
161-164.5 °C(Press: 0.07 Torr)
Density 
0.9220 g/cm3
storage temp. 
−20°C
solubility 
Chloroform (Sparingly), Methanol (Slightly)
pka
4.76±0.10(Predicted)
form 
Oil
color 
Colourless
Stability:
Light Sensitive
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D3659
Product name
cis-7,10,13,16-Docosatetraenoic acid
Purity
≥98% (GC)
Packaging
25mg
Price
$199
Updated
2024/03/01
Cayman Chemical
Product number
90300
Product name
Adrenic Acid
Purity
≥98%
Packaging
10mg
Price
$28
Updated
2024/03/01
Cayman Chemical
Product number
90300
Product name
Adrenic Acid
Purity
≥98%
Packaging
25mg
Price
$63
Updated
2024/03/01
Cayman Chemical
Product number
90300
Product name
Adrenic Acid
Purity
≥98%
Packaging
50mg
Price
$117
Updated
2024/03/01
Cayman Chemical
Product number
90300
Product name
Adrenic Acid
Purity
≥98%
Packaging
100mg
Price
$207
Updated
2024/03/01
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ADRENIC ACID Chemical Properties,Usage,Production

Description

Adrenic acid is a naturally occurring polyunsaturated fatty acid (PUFA) formed through a 2-carbon chain elongation of arachidonic acid. It is present in the adrenal glands, brain, testis, and kidney. Although there is trace metabolism of adrenic acid in the forebrain, the renal medulla is the only tissue which readily metabolizes the acid through cyclooxygenase activity. The primary metabolite of adrenic acid in the rabbit kidney is 1a,1b-dihomo prostaglandin E2.

Chemical Properties

Docosa tetra enoic acid designates any straight chain 22:4 fatty acid.
One isomer is of particular interest :
all-cis-7,10,13,16-docosa tetra enoic acid is an ω-6 fatty acid with the trivial name adrenic acid. This is a naturally occurring polyunsaturated fatty acid formed through a 2-carbon chain elongation of arachidonic acid. It is one of the most abundant fatty acids in the early human brain.

Uses

Adrenic acid is considered a sort of storage form of arachidnoic acid because it can be retro-converted into arachidonic acid by enzymes. Arachidonic acid is relatively abundant especially in the phospholipids that are found in cellular membranes, and it is precursor for many hormone-like signaling molecules, e.g. prostaglandins and leukotrienes. It shall be liberated from the phospholipids by phospholipase enzymes before it can be converted into these signaling molecules. Omnivorous humans also consume small amounts of arachidonic acid with the diet, since arachidonic acid is found in small amounts in all animal products. Arachidonic acid is not found in higher plants. Arachidonic acid serves many important functions in the body, e.g. as a structural element in membrane phospholipids, and as precursor for signalling.

Uses

cis-7,10,13,16-Docosatetraenoic Acid has been identified as a protein kinase inhibitor, affecting serotonin levels in studies.

Definition

ChEBI: All-cis-docosa-7,10,13,16-tetraenoic acid is the all-cis-isomer of a C22 polyunsaturated fatty acid having four double bonds in the 7-, 10-, 13- and 16-positions. One of the most abundant fatty acids in the early human brain. It has a role as a human metabolite and an algal metabolite. It is a docosatetraenoic acid and an omega-6 fatty acid. It is a conjugate acid of an all-cis-docosa-7,10,13,16-tetraenoate.

Enzyme inhibitor

This long-chain, unsaturated fatty acid (FWfree-acid = 332.53 g/mol; CAS 28874-58-0), also known as adrenic acid and (7Z,10Z,13Z,16Z)- docosatetraenoic acid, inhibits arachidonyl-CoA synthetase, orarachidonate:CoA ligase and prostaglandin biosynthesis.

ADRENIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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ADRENIC ACID Suppliers

Canada 1 China 48 Germany 2 Switzerland 1 United Kingdom 1 United States 12 Global 65
MedBioPharmaceutical Technology Inc
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ChemStrong Scientific Co.,Ltd
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View Lastest Price from ADRENIC ACID manufacturers

Henan Fengda Chemical Co., Ltd
Product
ADRENIC ACID 28874-58-0
Price
US $10.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-28

28874-58-0, ADRENIC ACIDRelated Search:

Nervonic acid Vitamin B12 Eicosapentaenoic acid ethyl ester CIS-6,9,12,15-OCTADECATETRAENOIC ACID*SO DIUM cis-11-Eicosenoic acid DELTA 7 CIS, 10 CIS,13 CIS, 16 CIS DOCOSATETRAENOIC ACID ETHYL ESTER ADRENIC ACID 3(R,S)-HYDROXY-7(Z),10(Z),13(Z),16(Z)-DOCOSATETRAENOIC ACID DELTA 7 CIS, 10 CIS,13 CIS, 16 CIS DOCOSATETRAENOIC ACID METHYL ESTER 3(R,S)-HYDROXY-7(Z),10(Z),13(Z),16(Z)-DOCOSATETRAENOIC ACID METHYL ESTER

  • CIS-7,10,13,16,19-DOCOSA-TETRAENOIC ACID
  • CIS-7,10,13,16-DOCOSA-TETRAENOIC ACID
  • DOCOSATETRAENOIC ACID
  • DOCOSA-7Z,10Z,13Z,16Z-PENTAENOIC ACID
  • DOCOSA-7Z,10Z,13Z,16Z-TETRAENOIC ACID
  • cis-7,10,13,16-Docosatetraenoic acid, C22:4n6
  • 7Z,10Z,13Z,16Z-DOCOSATETRAENOIC ACID
  • ADRENIC ACID
  • (All-Z)-7,10,13,16-docosatetraenoic acid
  • 7,10,13,16-Docosatetraenoic acid, (all-Z)-
  • 7,10,13,16-Docosatetraenoic acid (all-cis)
  • (7Z,10Z,13Z,16Z)-Docosa-7,10,13,16-tetraenoic acid
  • Adrenic Acid (Solution in ethanol)
  • Adrenic Acid (22:4, n-6)
  • 7,10,13,16-Docosatetraenoic acid, (7Z,10Z,13Z,16Z)-
  • Adrenic acid(cis-7,10,13,16)(C22:4)
  • all-cis-docosa-7,10,13,16-tetraenoicaci
  • Endogenous Metabolite,vascular,Inhibitor,fatty,Adrenic Acid,polyunsaturated,inflammation,inhibit
  • Ethyl Acetate Impurity 104
  • C22:4 cis-7.10.13.16-Docosatetraenoic Acid
  • 28874-58-0
  • C5H11CHCHCH24CH24COOH
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