ChemicalBook > CAS DataBase List > Nervonic acid

Nervonic acid

Product Name
Nervonic acid
CAS No.
506-37-6
Chemical Name
Nervonic acid
Synonyms
tetracosenic acid;15-TETRACOSENOIC ACID;CIS-15-TETRACOSENOIC ACID;SELACHOLEIC ACID;(Z)-Tetracos-15-enoic acid;selacholeic;cis-15-Teracosenoic acid;neuro acid;Nervonic aci;NERVONIC ACID
CBNumber
CB5304545
Molecular Formula
C24H46O2
Formula Weight
366.62
MOL File
506-37-6.mol
More
Less

Nervonic acid Property

Melting point:
42-43 °C (lit.)
Boiling point:
459.84°C (rough estimate)
Density 
0.9009 (rough estimate)
refractive index 
1.4806 (estimate)
Flash point:
>230 °F
storage temp. 
-20°C
solubility 
Chloroform (Slightly), Hexanes (Very Slightly)
pka
4.78±0.10(Predicted)
form 
Liquid
color 
White to Pale Yellow
BRN 
1728551
InChI
InChI=1S/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9-
InChIKey
GWHCXVQVJPWHRF-KTKRTIGZSA-N
SMILES
C(O)(=O)CCCCCCCCCCCCC/C=C\CCCCCCCC
LogP
10.890 (est)
CAS DataBase Reference
506-37-6(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
8-10
HS Code 
2916.19.3000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
87117
Product name
Nervonic acid
Purity
analytical standard
Packaging
100mg
Price
$147
Updated
2024/03/01
TCI Chemical
Product number
T1642
Product name
cis-15-Tetracosenoic Acid
Purity
>95.0%(GC)
Packaging
1g
Price
$319
Updated
2024/03/01
Cayman Chemical
Product number
13940
Product name
Nervonic Acid
Purity
≥95%
Packaging
100mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
13940
Product name
Nervonic Acid
Purity
≥95%
Packaging
250mg
Price
$92
Updated
2024/03/01
Sigma-Aldrich
Product number
N1514
Product name
Nervonic acid
Purity
≥99% (capillary GC)
Packaging
100mg
Price
$78.5
Updated
2024/03/01
More
Less

Nervonic acid Chemical Properties,Usage,Production

Description

Nervonic acid, also known as shark oil acid, is a monounsaturated omega-9 fatty acid that exists in nerve tissue and fish oil. It was first discovered in shark brain and is a component of cerebroside, the main source of in shark brain and shark oil. It is also found in the sphingolipids of white matter in human brain. It is the only dual-action miracle substance that can repair nerve fibers that unblock damaged nerve pathways in the brain and promote nerve cell regeneration. Nervonic acid has been identified as important in the biosynthesis of nerve cell myelin. It is used in the treatment of disorders involving demyelination, such as adrenoleukodystrophy and multiple sclerosis where there is a decreased level of nervonic acid in sphingolipids.

Occurrence

Nervonic acid is abundant in King Salmon ( Chinook ) with 140 mg/100g, yellow mustard seed 83 mg/100g , flax seed 64 mg/ 100g, Sockeye salmon 40 mg/100g, sesame seed 35mg/100g, and macademia nuts 18 mg/100g.

Uses

Found in sphingolipids of the white matter of the human brain, neuronic acid is the only magical substance with a dual role in brain development, repairing nerve fibers, unblocking damaged neural pathways in the brain, and promoting nerve cell regeneration. Neuroic acid is very important in the biosynthesis of nerve cell myelin, which together with lignoceric acid accounts for 60% of the acylated fatty acids in white matter sphingomyelin. In demyelinating diseases such as adrenoleukodystrophy and multiple sclerosis, the amount of neuronic acid acylated to sphingolipids is highly reduced, and supplements rich in this fatty acid have been used to help treat these demyelinating diseases.

Definition

ChEBI: Nervonic Acid is a monounsaturated fatty acid with a 24-carbon backbone and the sole double bond originating from the 9th carbon from the methyl end, with this bond in the cis- configuration. It is a metabolite found in the aging mouse brain.

Preparation

Nervonic acid was shown to be identical with selachaleic acid isolated from whale oils. It is obvious that nervonic acid is probably the cis form of erucylacetic acid. Erucylacetic acid has been prepared from erucyl alcohol through the bromide and malonic ester synthesis and has been shown to be identical with nervonic acid obtained from hydrolysis of the cerebroside isolated from human brains.
Nervonic acid is also produced from oleic acid, that undergoes three consecutive chain elongation steps, catalyzed by elongases.Two carbon units are added in each step, with production of gadoleic acid, erucic acid, and finally, nervonic acid.

General Description

Nervonic acids are the products of desaturation and elongation processes of various fatty acids such as palmitic acid, stearic acid, oleic acid, etc.

Biochem/physiol Actions

Nervonic acid (C24:1), a component of membrane sphingolipids and phosphatidylethanolamines, may be a useful predictor of chronic kidney disease mortality and diabetes. Nervonic acid oils are being studied for pharmaceutical, nutraceutical and industrial applications. Nervonic acid is a major component of Lunaria oil.

Source

Sources of Nervonic acid include oil crop seeds, oil-producing microalgae and other microorganisms. Transgenic technology can also be used to improve the source and production of Nervonic acid.

Nervonic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Nervonic acid Suppliers

Wuxi Fuze Pharmaceutical Co., Ltd.
Tel
0510-83594580 18012359489
Email
sales@further-pharm.com
Country
China
ProdList
7
Advantage
58
Shandong Yuanlitai Nutratech Co., Ltd,
Tel
18980869808
Email
info@yltnutra.com
Country
China
ProdList
9
Advantage
58
ShenZhen Dieckmann Bio-Pharm Co.,LTD
Tel
+86-0755-89213952 18123776296
Fax
86-755-84813563
Email
service@dkmchem.com
Country
China
ProdList
111
Advantage
55
Nanjing puyi biotechnology co., LTD
Tel
025-58886740; 13814510036
Email
927565933@qq.com
Country
China
ProdList
1931
Advantage
58
Shaanxi Pioneer Biotech Co., Ltd.
Tel
029-029-86629612 18202932191
Email
sales3@pioneerbiotech.com
Country
China
ProdList
336
Advantage
55
Xi'an Lyna Bio-Tech Co., Ltd.
Tel
029-84161958 18629577295
Fax
029-84161958
Email
magic@lynabio.com
Country
China
ProdList
1090
Advantage
55
Shaanxi billion Kang Long biological technology co., LTD
Tel
17791478691
Fax
4009024560
Email
yklbiotech@163.com
Country
China
ProdList
409
Advantage
58
Hangzhou Weitai Biological Pharmaceutical Co., Ltd.
Tel
86-571-82358004 13588879771
Email
sales1@weitai-pharmaceutical.com
Country
China
ProdList
84
Advantage
58
Jiangxi ravel Biotechnology Co.,Ltd
Tel
400-880-2824 15608648206
Email
1987516016@qq.com
Country
China
ProdList
2772
Advantage
58
SHANDONG XINGRUNDA CHEMICAL CO.,LTD
Tel
18615348689 18615348689
Email
hclt1978@163.com
Country
China
ProdList
14
Advantage
58
More
Less

View Lastest Price from Nervonic acid manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.
Product
Nervonic Acid 506-37-6
Price
US $0.00-0.00/g
Min. Order
10g
Purity
99% HPLC
Supply Ability
10000
Release date
2024-09-20
Sinoway Industrial co., ltd.
Product
Nervonic Acid 506-37-6
Price
US $0.00/KG
Min. Order
2KG
Purity
90% up
Supply Ability
20 tons
Release date
2021-07-07
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Nervonic acid 506-37-6
Price
US $20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/Week
Release date
2024-05-06

506-37-6, Nervonic acidRelated Search:


  • 15-TETRACOSENOICACID,STANDARDFORGC
  • selacholeic
  • CIS-15-TETRACOSENOIC ACID
  • C24:1 (CIS-15) ACID
  • DELTA 15 CIS TETRACOSENOIC ACID
  • 15-TETRACOSENOIC ACID
  • NERVONIC ACID
  • NERVONIC ACID (CIS)
  • SELACHOLEIC ACID
  • 15-Tetracosenoic acid,(15Z)-
  • cis-15-Teracosenoic acid
  • (E)-tetracos-15-enoic acid
  • NERVONIC ACID 98%(RG)
  • CIS-15-TETRACOSENICACID
  • tetracosenic acid
  • Selacholeic Acid 15Z-Tetracosenic Acid
  • cis-15-Tetracosenoic acid, Selacholeic acid
  • (15Z)-Tetracosenoic acid
  • (Z)-Tetracos-15-enoic acid
  • (15Z)-15-Tetracosenoic acid
  • (Z)-15-Tetracosenoic acid
  • Nervonic acid,cis-15-Tetracosenoic acid, Selacholeic acid
  • 8-Pentadecene-1-carboxylic acid
  • Physetolic acid
  • 15-cis-Tetracosenoic acid
  • Nervonic Acid Selacholeic Acid
  • Nervonic acid SynonyMs cis-15-Tetracosenoic acid
  • Nervonic aCld
  • Nervonic aci
  • Nervonic acid 506-37-6
  • neuro acid
  • Nervonic Acid(C24:1)
  • Natural Nervonic acid
  • Nervonic acid 90%?
  • Nerve acid 90%
  • Neuritic acid
  • Neuroic acid 90%
  • Nervonic acid,95%
  • Cis-15-TatracosanicAcidl
  • Cis-15-Tetracosenoic acid/Nervonic Acid
  • 15-cis-Tetracosenoic acid in isooctane
  • C24:1 15-Tetracosenoic (Nervonic) Acid
  • 506-37-6
  • C23H45COOH
  • CH3CH27CHCHCH213COOHcis
  • C24H46O2
  • Others
  • Unsaturated fatty acids and derivatives
  • Fatty Acids
  • Lipids
  • NA - NI
  • Monoenoic fatty acids
  • Biochemicals and Reagents
  • Analytical Standards
  • BioChemical
  • Analytical Chromatography Product Catalog
  • Alphabetic
  • Unsaturated Higher Fatty Acids