Nervonic acid
- Product Name
- Nervonic acid
- CAS No.
- 506-37-6
- Chemical Name
- Nervonic acid
- Synonyms
- tetracosenic acid;15-TETRACOSENOIC ACID;CIS-15-TETRACOSENOIC ACID;SELACHOLEIC ACID;(Z)-Tetracos-15-enoic acid;selacholeic;cis-15-Teracosenoic acid;neuro acid;Neural acid;Nervonic aci
- CBNumber
- CB5304545
- Molecular Formula
- C24H46O2
- Formula Weight
- 366.62
- MOL File
- 506-37-6.mol
Nervonic acid Property
- Melting point:
- 42-43 °C (lit.)
- Boiling point:
- 459.84°C (rough estimate)
- Density
- 0.9009 (rough estimate)
- refractive index
- 1.4806 (estimate)
- Flash point:
- >230 °F
- storage temp.
- -20°C
- solubility
- Chloroform (Slightly), Hexanes (Very Slightly)
- pka
- 4.78±0.10(Predicted)
- form
- Liquid
- color
- White to Pale Yellow
- biological source
- plant
- BRN
- 1728551
- InChI
- InChI=1S/C24H46O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24(25)26/h9-10H,2-8,11-23H2,1H3,(H,25,26)/b10-9-
- InChIKey
- GWHCXVQVJPWHRF-KTKRTIGZSA-N
- SMILES
- C(O)(=O)CCCCCCCCCCCCC/C=C\CCCCCCCC
- LogP
- 10.890 (est)
- CAS DataBase Reference
- 506-37-6(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 87117
- Product name
- Nervonic acid
- Purity
- analytical standard
- Packaging
- 100mg
- Price
- $151
- Updated
- 2025/07/31
- Product number
- T1642
- Product name
- cis-15-Tetracosenoic Acid
- Purity
- >95.0%(GC)
- Packaging
- 1g
- Price
- $315
- Updated
- 2025/07/31
- Product number
- 13940
- Product name
- Nervonic Acid
- Purity
- ≥95%
- Packaging
- 100mg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 13940
- Product name
- Nervonic Acid
- Purity
- ≥95%
- Packaging
- 250mg
- Price
- $92
- Updated
- 2024/03/01
- Product number
- N1514
- Product name
- Nervonic acid
- Purity
- ≥99% (capillary GC)
- Packaging
- 100mg
- Price
- $73.44
- Updated
- 2025/07/31
Nervonic acid Chemical Properties,Usage,Production
Description
Nervonic acid, also known as shark oil acid, is a monounsaturated omega-9 fatty acid that exists in nerve tissue and fish oil. It was first discovered in shark brain and is a component of cerebroside, the main source of in shark brain and shark oil. It is also found in the sphingolipids of white matter in human brain.
Occurrence
Nervonic acid is abundant in King Salmon ( Chinook ) with 140 mg/100g, yellow mustard seed 83 mg/100g , flax seed 64 mg/ 100g, Sockeye salmon 40 mg/100g, sesame seed 35mg/100g, and macademia nuts 18 mg/100g.
Uses
Neuroic acid is very important in the biosynthesis of nerve cell myelin, which together with lignoceric acid accounts for 60% of the acylated fatty acids in white matter sphingomyelin. In demyelinating diseases such as adrenoleukodystrophy and multiple sclerosis, the amount of neuronic acid acylated to sphingolipids is highly reduced, and supplements rich in this fatty acid have been used to help treat these demyelinating diseases.
Application
Nervonic acid (NA) is a very-long-chain monounsaturated fatty acid that plays crucial roles in brain development and has attracted widespread research interest. Nervonic acid can be used in nutraceutical, pharmaceutical, and chemical industries.
Definition
ChEBI: Nervonic Acid is a monounsaturated fatty acid with a 24-carbon backbone and the sole double bond originating from the 9th carbon from the methyl end, with this bond in the cis- configuration. It is a metabolite found in the aging mouse brain.
Preparation
Nervonic acid was shown to be identical with selachaleic acid isolated from whale oils. It is obvious that nervonic acid is probably the cis form of erucylacetic acid. Erucylacetic acid has been prepared from erucyl alcohol through the bromide and malonic ester synthesis and has been shown to be identical with nervonic acid obtained from hydrolysis of the cerebroside isolated from human brains.
Nervonic acid is also produced from oleic acid, that undergoes three consecutive chain elongation steps, catalyzed by elongases.Two carbon units are added in each step, with production of gadoleic acid, erucic acid, and finally, nervonic acid.
benefits
Nervonic acid (NA, a monounsaturated long-chain fatty acid) has been found to alleviate neurodegeneration. In humans, abnormal NA levels are closely associated with a higher risk of developing neurological or psychiatric disorders such as psychosis, schizophrenia, or attention deficit disorder. Studies have shown that NA treatment can improve cognitive function, prevent demyelination and oligodendrocyte loss or apoptosis, improve cerebral blood flow, and upregulate brain-derived neurotrophic factor and myelin basic protein genes. In addition, NA can not only stimulate adipogenesis by regulating signaling pathways in human MSCs, but also improve the results of fat transplantation by reducing inflammation and stimulating angiogenesis.
Biological Functions
Nervonic acid is the only dual-action miracle substance that can repair nerve fibers that unblock damaged nerve pathways in the brain and promote nerve cell regeneration. It has been identified as important in the biosynthesis of nerve cell myelin. It is used in the treatment of disorders involving demyelination, such as adrenoleukodystrophy and multiple sclerosis where there is a decreased level of nervonic acid in sphingolipids.
General Description
Nervonic acids are the products of desaturation and elongation processes of various fatty acids such as palmitic acid, stearic acid, oleic acid, etc.
Biochem/physiol Actions
Nervonic acid (C24:1), a component of membrane sphingolipids and phosphatidylethanolamines, may be a useful predictor of chronic kidney disease mortality and diabetes. Nervonic acid oils are being studied for pharmaceutical, nutraceutical and industrial applications. Nervonic acid is a major component of Lunaria oil.
Source
Sources of Nervonic acid include oil crop seeds, oil-producing microalgae and other microorganisms. Transgenic technology can also be used to improve the source and production of Nervonic acid.
Nervonic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Nervonic acid Suppliers
- Tel
- 13336346583
- Wangxh010@163.com
- Country
- China
- ProdList
- 9
- Advantage
- 58
- Tel
- 18980869808
- info@yltnutra.com
- Country
- China
- ProdList
- 17
- Advantage
- 58
- Tel
- +86-0755-89213952 18123776296
- Fax
- 86-755-84813563
- service@dkmchem.com
- Country
- China
- ProdList
- 111
- Advantage
- 55
- Tel
- 13814510036
- 927565933@qq.com
- Country
- China
- ProdList
- 1933
- Advantage
- 58
- Tel
- 029-029-86629612 18202932191
- sales3@pioneerbiotech.com
- Country
- China
- ProdList
- 300
- Advantage
- 55
- Tel
- +86-18629577295; 17709273212
- Fax
- 029-84161958
- ludy@lynabio.com
- Country
- China
- ProdList
- 1055
- Advantage
- 55
- Tel
- 17791478691
- Fax
- 4009024560
- yklbiotech@163.com
- Country
- China
- ProdList
- 317
- Advantage
- 58
- Tel
- 0571-82358004 13588879771
- info@weitai-pharmaceutical.com
- Country
- China
- ProdList
- 68
- Advantage
- 58
- Tel
- 400-880-2824 15608648206
- 1987516016@qq.com
- Country
- China
- ProdList
- 2671
- Advantage
- 58
- Tel
- 0534-18615348689 18615348689
- hclt1978@163.com
- Country
- China
- ProdList
- 35
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9310
- Advantage
- 66
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- +86-571-85224801; 13588483690
- Fax
- 0571-85241599
- chemipanda2010@163.com
- Country
- China
- ProdList
- 111
- Advantage
- 62
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18729
- Advantage
- 57
- Tel
- 0531-0531-58897003 15550412551
- Fax
- 0531-58897003
- market@jnchsd.com
- Country
- China
- ProdList
- 229
- Advantage
- 62
- Tel
- 400-1166-196 18981987031
- Fax
- 028-84555506 800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 11705
- Advantage
- 57
- Tel
- +86 (573) 82222445 (0)18006601000 452520369
- Fax
- +86 (573) 82222643
- sales@maya-r.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 0571-82693216
- Fax
- +86-571-82880190
- info@yuhaochemical.com
- Country
- China
- ProdList
- 6387
- Advantage
- 52
- Tel
- 86-21-34053660
- Fax
- 86-21-34053661
- sale@labgogo.com
- Country
- China
- ProdList
- 9865
- Advantage
- 52
- Tel
- 025-84430028 13815430202
- sale02@cqherb.com
- Country
- China
- ProdList
- 294
- Advantage
- 59
- Tel
- 025-66113011 17798518460
- Fax
- (1)02557626880
- cfzhang@aikonchem.com
- Country
- China
- ProdList
- 19913
- Advantage
- 55
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 22514
- Advantage
- 55
- Tel
- 400-6206333 13167063860
- Fax
- 021-50323701
- anhua.mao@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- 021-51320588
- Fax
- 0086-21-51320502
- tauto@tautobiotech.com
- Country
- China
- ProdList
- 3988
- Advantage
- 66
- Tel
- 025-57798810
- Fax
- 025-57019371
- sales@sunlidabio.com
- Country
- China
- ProdList
- 3239
- Advantage
- 55
- Tel
- 021-021-33632979 15002134094
- Fax
- 021-33632979
- marketing@targetmol.com
- Country
- China
- ProdList
- 7783
- Advantage
- 58
- Tel
- 021-33632979
- Fax
- 021-34692979
- info@tsbiochem.com
- Country
- China
- ProdList
- 8065
- Advantage
- 58
- Tel
- 022-65378550-8551
- Fax
- +86-022-2532-9655
- contact@altascientific.com
- Country
- China
- ProdList
- 2773
- Advantage
- 58
- Tel
- 028-81700200 18116577057
- Fax
- 028-81705658
- 3003855609@qq.com
- Country
- China
- ProdList
- 7778
- Advantage
- 56
- Tel
- 0510-85629785 18013409632
- Fax
- 051085625359
- sales@reading-chemicals.com
- Country
- China
- ProdList
- 15178
- Advantage
- 58
- Tel
- 027-87465837 19945049750
- Fax
- 027-8777-2287
- sales@finetechnology-ind.com
- Country
- China
- ProdList
- 9637
- Advantage
- 58
- Tel
- 0512-87182056 18013166090
- Fax
- 0512-87182056
- lingling.qi@yacoo.com.cn
- Country
- China
- ProdList
- 6295
- Advantage
- 60
- Tel
- 15221275939
- Fax
- 021-50706099
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 15873
- Advantage
- 55
- Tel
- 0571-87396432
- Fax
- 0571-87396431
- sales@jhechem.com
- Country
- China
- ProdList
- 14912
- Advantage
- 59
- Tel
- 027-88395709
- Fax
- 027-88391805
- Country
- China
- ProdList
- 429
- Advantage
- 50
- Tel
- 18905173768
- Fax
- 025-83263139
- 52513593@qq.com
- Country
- China
- ProdList
- 2331
- Advantage
- 50
- Tel
- 13096311329 028-88469284 616445927
- Fax
- 028-88469284
- 616445927@qq.com
- Country
- China
- ProdList
- 2874
- Advantage
- 50
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51395
- Advantage
- 80
- Tel
- 027-59207879 1972026995 18140587686
- Fax
- QQ：1972026995
- sales@3600chem.com
- Country
- China
- ProdList
- 4447
- Advantage
- 55
- Tel
- 022-6537-8550 15522853686
- Fax
- 022-2532-9655
- sales@altasci.com.cn
- Country
- China
- ProdList
- 4511
- Advantage
- 55
- Tel
- 029-86107037; 15829389671
- Fax
- 029-86107037
- info@konochemical.com
- Country
- China
- ProdList
- 412
- Advantage
- 55
- Tel
- 18607101326 15172504745
- Fax
- +86-27-84254680
- aileen@chemfaces.com
- Country
- China
- ProdList
- 6905
- Advantage
- 55
- Tel
- 21-619849051-1 18521059765
- synchempharma@aliyun.com
- Country
- China
- ProdList
- 6468
- Advantage
- 55
- Tel
- 4000-819-385 010-62329685 13718666987
- Fax
- 010-62340519
- Country
- China
- ProdList
- 1971
- Advantage
- 55
- Tel
- 021-38751876 15000076078
- Fax
- 021-50275764
- Info@rochipharma.com
- Country
- China
- ProdList
- 611
- Advantage
- 55
View Lastest Price from Nervonic acid manufacturers
- Product
- Nervonic acid 506-37-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 90%
- Supply Ability
- 1
- Release date
- 2025-09-05
- Product
- Nervonic Acid 506-37-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 85%;90%
- Supply Ability
- 500KG
- Release date
- 2025-08-19
- Product
- Nervonic acid 506-37-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 1000kg
- Release date
- 2025-04-27