Description References
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Arachidonic acid

Description References
Product Name
Arachidonic acid
CAS No.
506-32-1
Chemical Name
Arachidonic acid
Synonyms
ARA;Arachidonate;Arachidonic;5,8,11,14-EICOSATETRAENOIC ACID;icosa-5,8,11,14-tetraenoic acid;Arachidonic Acid (peroxide free);(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid;20:4n-6;CIS-5,8,11,14-EICOSATETRAENOIC ACID;Single-Use Arachidonic Acid (peroxide free)
CBNumber
CB8112259
Molecular Formula
C20H32O2
Formula Weight
304.47
MOL File
506-32-1.mol
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Arachidonic acid Property

Melting point:
-49 °C (lit.)
Boiling point:
169-171 °C/0.15 mmHg (lit.)
Density 
0.922 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.4872(lit.)
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
ethanol: ≥10 mg/mL
form 
oil
pka
4.75±0.10(Predicted)
color 
colorless to light yellow
Water Solubility 
PRACTICALLY INSOLUBLE
Merck 
14,765
BRN 
1713889
Concentration
1 mCi/ml
Solvent
Ethanol under argon
Specific Activity
200-240 Ci/mmol
Stability:
Light Sensitive, Temperature Sensitive
InChIKey
YZXBAPSDXZZRGB-DOFZRALJSA-N
LogP
6.99
CAS DataBase Reference
506-32-1(CAS DataBase Reference)
NIST Chemistry Reference
Arachidonic acid(506-32-1)
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Safety

Risk Statements 
19
Safety Statements 
24/25-19
RIDADR 
UN1170 - class 3 - PG 2 - Ethanol
WGK Germany 
3
RTECS 
CE6675000
8-10-23
HS Code 
29161900
Toxicity
dns-mus:mmr 10 mg/L CRNGDP 5,1123,84
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A-122
Product name
Arachidonic acid
Purity
1.0?mg/mL in ethanol, certified reference material, Cerilliant?
Packaging
1mL
Price
$191
Updated
2024/03/01
Sigma-Aldrich
Product number
181198
Product name
Arachidonic Acid - CAS 506-32-1 - Calbiochem
Purity
Precursor for prostaglandins, prostacyclin, and thromboxane.
Packaging
1G
Price
$378
Updated
2024/03/01
Sigma-Aldrich
Product number
10931
Product name
Arachidonic acid
Purity
>95.0% (GC)
Packaging
250mg
Price
$185
Updated
2024/03/01
Sigma-Aldrich
Product number
10931
Product name
Arachidonic acid
Purity
>95.0% (GC)
Packaging
1g
Price
$463
Updated
2024/03/01
Sigma-Aldrich
Product number
SAB1412610
Product name
ANTI-FOXC1 antibody produced in mouse
Purity
clone 1E11, purified immunoglobulin, buffered aqueous solution
Packaging
100μg
Price
$503
Updated
2023/01/07
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Arachidonic acid Chemical Properties,Usage,Production

Description

Arachidonic acid belongs to a kind of polyunsaturated omega-6 fatty acid, which is highly biologically relevant. It is abundantly distributed in brain, muscles and liver. It is the precursor for all prostaglandins, thromboxanes, and leukotrienes. Most cellular arachidonic acid is esterified in the membrane phospholipids. It is an important second messenger of cellular signalling participating in the regulation of signaling enzymes including PLC-γ, PLC-δ, and PKC-α, -β, and -γ isoforms. In addition, arachidonic acid acts as key inflammatory intermediate as well as avasodilator. Generally, the body can synthesize the arachidonic acid through linoleic acid. However, upon linoleic acid deficiency, it is necessary to supplement arachidonic acid from the diets. Food sources of arachidonic acid include meat, eggs and some fishes. Alternatively, we can also have arachidonic acid supplements.

References

http://www.fitday.com/fitness-articles/nutrition/healthy-eating/what-is-arachidonic-acid.html
https://en.wikipedia.org/wiki/Arachidonic_acid
https://www.caymanchem.com/product/90010

Description

Arachidonic acid (AA, sometimes ARA) is a polyunsaturated omega-6 fatty acid 20:4(ω-6). It is the counterpart to the saturated arachidic acid found in peanut oil, (L. arachis – peanut.).

Chemical Properties

In chemical structure, arachidonic acid is a carboxylic acid with a 20-carbon chain and four cis-double bonds; the first double bond is located at the sixth carbon from the omega end.
Some chemistry sources define 'arachidonic acid' to designate any of the eicosatetraenoic acids. However, almost all writings in biology, medicine and nutrition limit the term to all-cis-5,8,11,14- eicosatetraenoic acid.

Chemical Properties

liquid

Uses

An unsaturated omega-6 fatty acid constituent of the phospholipids of cell membranes

Uses

arachidonic acid is an ingredient with skin-smoothing, emollient, and healing properties. Arachidonic acid is an omega-6 essential fatty acid naturally occurring in the skin and considered critical for appropriate skin metabolism. It is a constituent of vitamin F.

Uses

Arachidonic Acid is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides.

Definition

ChEBI: A long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14.

General Description

A Certified Spiking Solution? suitable for use in mass spectrometry-based fatty acid testing applications such as assessment of cardiovascular disease risk and fatty acid deficiency, and detection and quantification of arachidonic acid in nutraceuticals and dietary supplements. Arachidonic acid (cis-5,8,11,14), sometimes referred to as AA or ARA, is a polyunsaturated omega-6 fatty acid. Studies suggests that ARA as well as other fatty acids can serve as biomarkers for cardiovascular disease, and nutritional and metabolic disorders.

Biological Activity

Endogenous free fatty acid released from phospholipids by phospholipase A 2 . Important cellular signaling mediator and precursor of eicosanoids. Metabolized by lipoxygenases, cyclooxygenases and cytochrome P450 monooxygenases.

Biochem/physiol Actions

Arachidonic acid stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules (collagen IV and vitronectin) .

Safety Profile

Poison by intravenous route.Experimental reproductive effects. Mutation datareported. When heated to decomposition it emits acridsmoke and irritating fumes.

Carcinogenicity

In vitro and in vivo studies indicate that inhibition of arachidonic acid metabolism inhibits the growth of malignant cells, including head and neck squamous cell carcinoma, and implicates arachadonic acid in facilitating the metastasis of these tumor cells. Arachidonic acid reaction with cyclooxygenase and lipoxygenases yield eicosanoids that can mediate prostate cancer proliferation and enhance both tumor vascularization and metastasis. Cytochrome P450 arachidonic acid epoxygenases promote cell proliferation and inhibit apoptosis in endothelial cells.

Arachidonic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Arachidonic acid Suppliers

Will Health Technology (Wuhan) Co., Ltd
Tel
027-59266979 18186610332
Email
1750669728@qq.com
Country
China
ProdList
150
Advantage
58
Hebei Zhentian Food Additives Co., Ltd.
Tel
0319-5925599 13373390591
Fax
0319 5925599
Email
13933732699@163.com
Country
China
ProdList
12185
Advantage
58
Shaanxi Pioneer Biotech Co., Ltd
Tel
029-86621125 18123784671
Email
sales@pioneerbiotech.com
Country
China
ProdList
500
Advantage
58
Pand (Shanghai) international trade Co., LTD
Tel
18662931292 18662931292
Email
3404730042@qq.com
Country
China
ProdList
4760
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9414
Advantage
66
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View Lastest Price from Arachidonic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Arachidonic acid 506-32-1
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-01-13
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Arachidonic Acid 506-32-1
Price
US $120.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-08
HebeiShuoshengImportandExportco.,Ltd
Product
Arachidonic acid 506-32-1
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-01

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