Arachidonic acid
Description References- Product Name
- Arachidonic acid
- CAS No.
- 506-32-1
- Chemical Name
- Arachidonic acid
- Synonyms
- ARA;Arachidonate;Arachidonic;5,8,11,14-EICOSATETRAENOIC ACID;icosa-5,8,11,14-tetraenoic acid;Arachidonic Acid (peroxide free);(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid;20:4n-6;CIS-5,8,11,14-EICOSATETRAENOIC ACID;Single-Use Arachidonic Acid (peroxide free)
- CBNumber
- CB8112259
- Molecular Formula
- C20H32O2
- Formula Weight
- 304.47
- MOL File
- 506-32-1.mol
Arachidonic acid Property
- Melting point:
- -49 °C (lit.)
- Boiling point:
- 169-171 °C/0.15 mmHg (lit.)
- Density
- 0.922 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.4872(lit.)
- Flash point:
- >230 °F
- storage temp.
- 2-8°C
- solubility
- ethanol: ≥10 mg/mL
- form
- oil
- pka
- 4.75±0.10(Predicted)
- color
- colorless to light yellow
- Water Solubility
- PRACTICALLY INSOLUBLE
- Merck
- 14,765
- BRN
- 1713889
- Concentration
- 1 mCi/ml
- Solvent
- Ethanol under argon
- Specific Activity
- 200-240 Ci/mmol
- Stability:
- Light Sensitive, Temperature Sensitive
- InChIKey
- YZXBAPSDXZZRGB-DOFZRALJSA-N
- LogP
- 6.99
- CAS DataBase Reference
- 506-32-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Arachidonic acid(506-32-1)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A-122
- Product name
- Arachidonic acid
- Purity
- 1.0?mg/mL in ethanol, certified reference material, Cerilliant?
- Packaging
- 1mL
- Price
- $191
- Updated
- 2024/03/01
- Product number
- 181198
- Product name
- Arachidonic Acid - CAS 506-32-1 - Calbiochem
- Purity
- Precursor for prostaglandins, prostacyclin, and thromboxane.
- Packaging
- 1G
- Price
- $378
- Updated
- 2024/03/01
- Product number
- 10931
- Product name
- Arachidonic acid
- Purity
- >95.0% (GC)
- Packaging
- 250mg
- Price
- $185
- Updated
- 2024/03/01
- Product number
- 10931
- Product name
- Arachidonic acid
- Purity
- >95.0% (GC)
- Packaging
- 1g
- Price
- $463
- Updated
- 2024/03/01
- Product number
- SAB1412610
- Product name
- ANTI-FOXC1 antibody produced in mouse
- Purity
- clone 1E11, purified immunoglobulin, buffered aqueous solution
- Packaging
- 100μg
- Price
- $503
- Updated
- 2023/01/07
Arachidonic acid Chemical Properties,Usage,Production
Description
Arachidonic acid belongs to a kind of polyunsaturated omega-6 fatty acid, which is highly biologically relevant. It is abundantly distributed in brain, muscles and liver. It is the precursor for all prostaglandins, thromboxanes, and leukotrienes. Most cellular arachidonic acid is esterified in the membrane phospholipids. It is an important second messenger of cellular signalling participating in the regulation of signaling enzymes including PLC-γ, PLC-δ, and PKC-α, -β, and -γ isoforms. In addition, arachidonic acid acts as key inflammatory intermediate as well as avasodilator. Generally, the body can synthesize the arachidonic acid through linoleic acid. However, upon linoleic acid deficiency, it is necessary to supplement arachidonic acid from the diets. Food sources of arachidonic acid include meat, eggs and some fishes. Alternatively, we can also have arachidonic acid supplements.
References
http://www.fitday.com/fitness-articles/nutrition/healthy-eating/what-is-arachidonic-acid.html
https://en.wikipedia.org/wiki/Arachidonic_acid
https://www.caymanchem.com/product/90010
Description
Arachidonic acid (AA, sometimes ARA) is a polyunsaturated omega-6 fatty acid 20:4(ω-6). It is the counterpart to the saturated arachidic acid found in peanut oil, (L. arachis – peanut.).
Chemical Properties
In chemical structure, arachidonic acid is a carboxylic acid with a 20-carbon chain and four cis-double bonds; the first double bond is located at the sixth carbon from the omega end.
Some chemistry sources define 'arachidonic acid' to designate any of the eicosatetraenoic acids. However, almost all writings in biology, medicine and nutrition limit the term to all-cis-5,8,11,14- eicosatetraenoic acid.
Chemical Properties
liquid
Uses
An unsaturated omega-6 fatty acid constituent of the phospholipids of cell membranes
Uses
arachidonic acid is an ingredient with skin-smoothing, emollient, and healing properties. Arachidonic acid is an omega-6 essential fatty acid naturally occurring in the skin and considered critical for appropriate skin metabolism. It is a constituent of vitamin F.
Uses
Arachidonic Acid is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides.
Definition
ChEBI: A long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14.
General Description
A Certified Spiking Solution? suitable for use in mass spectrometry-based fatty acid testing applications such as assessment of cardiovascular disease risk and fatty acid deficiency, and detection and quantification of arachidonic acid in nutraceuticals and dietary supplements. Arachidonic acid (cis-5,8,11,14), sometimes referred to as AA or ARA, is a polyunsaturated omega-6 fatty acid. Studies suggests that ARA as well as other fatty acids can serve as biomarkers for cardiovascular disease, and nutritional and metabolic disorders.
Biological Activity
Endogenous free fatty acid released from phospholipids by phospholipase A 2 . Important cellular signaling mediator and precursor of eicosanoids. Metabolized by lipoxygenases, cyclooxygenases and cytochrome P450 monooxygenases.
Biochem/physiol Actions
Arachidonic acid stimulates adhesion of MDA-MB-435 human metastatic cancer cells to extracellular matrix molecules (collagen IV and vitronectin) .
Safety Profile
Poison by intravenous route.Experimental reproductive effects. Mutation datareported. When heated to decomposition it emits acridsmoke and irritating fumes.
Carcinogenicity
In vitro and in vivo studies indicate that inhibition of arachidonic acid metabolism inhibits the growth of malignant cells, including head and neck squamous cell carcinoma, and implicates arachadonic acid in facilitating the metastasis of these tumor cells. Arachidonic acid reaction with cyclooxygenase and lipoxygenases yield eicosanoids that can mediate prostate cancer proliferation and enhance both tumor vascularization and metastasis. Cytochrome P450 arachidonic acid epoxygenases promote cell proliferation and inhibit apoptosis in endothelial cells.
Arachidonic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Arachidonic acid manufacturers
- Product
- Arachidonic Acid 506-32-1
- Price
- US $120.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-05-08
- Product
- Arachidonic acid 506-32-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-01-13
- Product
- Arachidonic acid 506-32-1
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-08-01