DAGO

Product Name: DAGO
CAS No.: 78123-71-4
Chemical Name: DAGO
Synonyms: DAGO;DAMGO;Dagol;Damge;DAMPGO;RX-783006;NIH 10891;DAMGO, 10 mM in DMSO;M.W. 513.59 C26H35N5O6;Tyr-D-Ala-Gly-MePhe-Gly-ol
CBNumber: CB2459705
Molecular Formula: C26H35N5O6
Formula Weight: 513.59
MOL File: 78123-71-4.mol

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DAGO Property

Boiling point:: 922.7±65.0 °C(Predicted)
Density: 1.271±0.06 g/cm3(Predicted)
storage temp.: -15°C
solubility: ≥40.7 mg/mL in EtOH; ≥40.7 mg/mL in H2O; ≥42.2 mg/mL in DMSO
form: solid
pka: 9.97±0.15(Predicted)
color: White
Water Solubility: Soluble in water (4 mM)
Sequence: H-Tyr-D-Ala-Gly-NMe-Phe-Gly-ol
Stability:: Hygroscopic
InChIKey: HPZJMUBDEAMBFI-RZPISPKSNA-N
SMILES: [C@H](C(=O)NCCO)(N(C)C(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)CC1C=CC=CC=1 |&1:0,15,20,r|

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 21553
Product name: DAMGO
Purity: ≥98%
Packaging: 1mg
Price: $35
Updated: 2021/12/16

Cayman Chemical

Product number: 21553
Product name: DAMGO
Purity: ≥98%
Packaging: 5mg
Price: $96
Updated: 2021/12/16

Cayman Chemical

Product number: 21553
Product name: DAMGO
Purity: ≥98%
Packaging: 10mg
Price: $175
Updated: 2021/12/16

Cayman Chemical

Product number: 21553
Product name: DAMGO
Purity: ≥98%
Packaging: 25mg
Price: $394
Updated: 2021/12/16

Tocris

Product number: 1171
Product name: DAMGO
Packaging: 1
Price: $83
Updated: 2021/12/16

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DAGO Chemical Properties,Usage,Production

Uses

DAMGO is an opioid receptor agonist (1,2). DAMGO can be used to investigate the analgesic mechanism of opioids. It has been shown that DAMGO can modulate the two-pore domain K(+) channels in the substantia gelatinosa neurons (3).

Definition

ChEBI: (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin is a peptide.

Biological Activity

Highly selective peptide agonist for the μ opioid receptor.

in vivo

DAMGO (i.v., 0.5-2 mg/kg) can produce significant anti-injury effects on injured paws of male Sprague-Dawley rats weighing 200-225 g in a dose-dependent manner, producing an effective and long-lasting analgesic effect^[4].

IC 50

μ Opioid Receptor/MOR

storage

-20°C (desiccate)

DAGO Preparation Products And Raw materials

Raw materials

Preparation Products

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DAGO Suppliers

China 118 France 1 Germany 3 Switzerland 1 The Netherlands 1 United Kingdom 3 United States 17 USA 1 Global 145

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15873
Advantage: 55

Creative Peptides

Tel
Email: info@creative-peptides.com
Country: United States
ProdList: 6083
Advantage: 56

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9119
Advantage: 58

Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 15951641583
Fax: 025-58361106-806
Email: zhao.xu@njpeptide.com
Country: China
ProdList: 9979
Advantage: 55

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View Lastest Price from DAGO manufacturers

Shanghai Chinqesen Biotechnology Co., Ltd.

Product: DAGO 78123-71-4
Price: US $30.00-20.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000000
Release date: 2023-10-30

78123-71-4, DAGORelated Search:

DAMGO [TYROSYL-3,5-3H, (DAGO)] ([125I]-TYR)-DAGO guanyl-DAMME DAGO [TYROSYL-3,5-3H] DAGO ACETATE SALT,DAGO, DAMGO, Tyr-D-Ala-Gly-N-methyl-Phe-Gly-ol FK 33-824 [3,5-DIIODO-TYR1]-DAGO,(3,5-DIIODO-TYR1)-DAGO ACOH,(3,5-DIIODO-TYR1)-DAGO ACETATE SALT,3,5-Diiodo-Tyr-D-Ala-Gly-N-Methyl-Phe-Gly-ol, [3,5-Diodo-Tyr1]-DAGO DAGO

Tyr-D-Ala-Gly-MePhe-Gly-ol

Tyr-D-Ala-Gly-MePhe-NH-(CH2)2OH

Tyr-D-Ala-Gly-N-methylphenylalanine-glycinol

TYR-D-ALA-GLY-N-ME-PHE-GLY-OL

TYR-D-ALA-GLY-N-METHYL-PHE-GLY-OL

DAMGO

DAGO

(D-ALA2,N-ME-PHE4,GLYCINOL5)-ENKEPHALIN

[D-ALA2, NME-PHE4, GLY-OL5]-ENKEPHALIN

[D-ALA2, N-ME-PHE4, GLY-OL]-ENKEPHALIN

[D-ALA2,N-METHYL-PHE4,GLY-OL5]-ENKEPHALIN

H-TYR-D-ALA-GLY-N-ME-PHE-GLYCINOL

ala(2)-mephe(4)-gly-ol(5)-enkephali

DAMGO >98% SYNTHETIC (D-ALA2,N-ME-PHE4,G LY

H-Tyr-D-Ala-Gly-N-Me-Phe-Gly-OL

M.W. 513.59 C26H35N5O6

L-Tyr-D-Ala-Gly-N-Methyl-L-Phe-Gly-OH

[D-Ala2,MePhe4,Gly-ol5]enkephalin

L-Tyr-D-Ala-Gly-N-Methyl-L-Phe-N-(2-hydroxyethyl)-NH2

RX-783006

2-Ala-4-mephe-5-Gly-enkephalin

Ala(2)-mephe(4)-Gly-ol(5) enkephalin

Dagol

Damge

Enkephalin, Ala(2)-mephe(4)-Gly-ol(5)-

[D-Ala(2),N-methyl-Phe(4),Gly(5)-ol]-enkephalin

3: PN: WO2009046859 PAGE: 98 claimed protein

DAMPGO

H-Tyr-D-Ala(Me)Phe-NH-CH2-OH

L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nalpha-methyl-L-phenylalaninamide

NIH 10891

PN: US20030176421 PAGE: 54-55 claimed protein

Tyr-D-Ala-Gly-(methyl)Phe-Gly-ol

(D-Ala2,N-Me-Phe4,Gly5-ol)enkephalin

L-Phenylalaninamide, L-tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nα-methyl-

DAMGO, mu opioid receptor agonist

DAMGO, 10 mM in DMSO

78123-71-4

C26H35N5O6

Peptide

Opioid receptor and opioid-like receptor