ChemicalBook > CAS DataBase List > DAGO

DAGO

Product Name: DAGO
CAS No.: 78123-71-4
Chemical Name: DAGO
Synonyms: DAGO;DAMGO;Dagol;Damge;DAMPGO;RX-783006;NIH 10891;DAMGO, 10 mM in DMSO;M.W. 513.59 C26H35N5O6;Tyr-D-Ala-Gly-MePhe-Gly-ol
CBNumber: CB2459705
Molecular Formula: C26H35N5O6
Formula Weight: 513.59
MOL File: 78123-71-4.mol

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DAGO Property

Boiling point:: 922.7±65.0 °C(Predicted)
Density: 1.271±0.06 g/cm3(Predicted)
storage temp.: -15°C
solubility: ≥40.7 mg/mL in EtOH; ≥40.7 mg/mL in H2O; ≥42.2 mg/mL in DMSO
form: solid
pka: 9.97±0.15(Predicted)
color: White
Water Solubility: Soluble in water (4 mM)
Sequence: H-Tyr-D-Ala-Gly-NMe-Phe-Gly-ol
Stability:: Hygroscopic
InChIKey: HPZJMUBDEAMBFI-RZPISPKSNA-N
SMILES: [C@H](C(=O)NCCO)(N(C)C(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)CC1C=CC=CC=1 |&1:0,15,20,r|

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 21553
Product name: DAMGO
Purity: ≥98%
Packaging: 1mg
Price: $35
Updated: 2021/12/16

Cayman Chemical

Product number: 21553
Product name: DAMGO
Purity: ≥98%
Packaging: 5mg
Price: $96
Updated: 2021/12/16

Cayman Chemical

Product number: 21553
Product name: DAMGO
Purity: ≥98%
Packaging: 10mg
Price: $175
Updated: 2021/12/16

Cayman Chemical

Product number: 21553
Product name: DAMGO
Purity: ≥98%
Packaging: 25mg
Price: $394
Updated: 2021/12/16

Tocris

Product number: 1171
Product name: DAMGO
Packaging: 1
Price: $83
Updated: 2021/12/16

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DAGO Chemical Properties,Usage,Production

Uses

DAMGO is an opioid receptor agonist (1,2). DAMGO can be used to investigate the analgesic mechanism of opioids. It has been shown that DAMGO can modulate the two-pore domain K(+) channels in the substantia gelatinosa neurons (3).

Definition

ChEBI: (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin is a peptide.

Biological Activity

Highly selective peptide agonist for the μ opioid receptor.

in vivo

DAMGO (i.v., 0.5-2 mg/kg) can produce significant anti-injury effects on injured paws of male Sprague-Dawley rats weighing 200-225 g in a dose-dependent manner, producing an effective and long-lasting analgesic effect^[4].

IC 50

μ Opioid Receptor/MOR

storage

-20°C (desiccate)

DAGO Preparation Products And Raw materials

Raw materials

Preparation Products

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DAGO Suppliers

China 118 France 1 Germany 3 Switzerland 1 The Netherlands 1 United Kingdom 3 United States 17 USA 1 Global 145

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View Lastest Price from DAGO manufacturers

Shanghai Chinqesen Biotechnology Co., Ltd.

Product: DAGO 78123-71-4
Price: US $30.00-20.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000000
Release date: 2023-10-30

78123-71-4, DAGORelated Search:

DAMGO [TYROSYL-3,5-3H, (DAGO)] ([125I]-TYR)-DAGO guanyl-DAMME DAGO [TYROSYL-3,5-3H] DAGO ACETATE SALT,DAGO, DAMGO, Tyr-D-Ala-Gly-N-methyl-Phe-Gly-ol FK 33-824 [3,5-DIIODO-TYR1]-DAGO,(3,5-DIIODO-TYR1)-DAGO ACOH,(3,5-DIIODO-TYR1)-DAGO ACETATE SALT,3,5-Diiodo-Tyr-D-Ala-Gly-N-Methyl-Phe-Gly-ol, [3,5-Diodo-Tyr1]-DAGO DAGO

Tyr-D-Ala-Gly-MePhe-Gly-ol

Tyr-D-Ala-Gly-MePhe-NH-(CH2)2OH

Tyr-D-Ala-Gly-N-methylphenylalanine-glycinol

TYR-D-ALA-GLY-N-ME-PHE-GLY-OL

TYR-D-ALA-GLY-N-METHYL-PHE-GLY-OL

DAMGO

DAGO

(D-ALA2,N-ME-PHE4,GLYCINOL5)-ENKEPHALIN

[D-ALA2, NME-PHE4, GLY-OL5]-ENKEPHALIN

[D-ALA2, N-ME-PHE4, GLY-OL]-ENKEPHALIN

[D-ALA2,N-METHYL-PHE4,GLY-OL5]-ENKEPHALIN

H-TYR-D-ALA-GLY-N-ME-PHE-GLYCINOL

ala(2)-mephe(4)-gly-ol(5)-enkephali

DAMGO >98% SYNTHETIC (D-ALA2,N-ME-PHE4,G LY

H-Tyr-D-Ala-Gly-N-Me-Phe-Gly-OL

M.W. 513.59 C26H35N5O6

L-Tyr-D-Ala-Gly-N-Methyl-L-Phe-Gly-OH

[D-Ala2,MePhe4,Gly-ol5]enkephalin

L-Tyr-D-Ala-Gly-N-Methyl-L-Phe-N-(2-hydroxyethyl)-NH2

RX-783006

2-Ala-4-mephe-5-Gly-enkephalin

Ala(2)-mephe(4)-Gly-ol(5) enkephalin

Dagol

Damge

Enkephalin, Ala(2)-mephe(4)-Gly-ol(5)-

[D-Ala(2),N-methyl-Phe(4),Gly(5)-ol]-enkephalin

3: PN: WO2009046859 PAGE: 98 claimed protein

DAMPGO

H-Tyr-D-Ala(Me)Phe-NH-CH2-OH

L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nalpha-methyl-L-phenylalaninamide

NIH 10891

PN: US20030176421 PAGE: 54-55 claimed protein

Tyr-D-Ala-Gly-(methyl)Phe-Gly-ol

(D-Ala2,N-Me-Phe4,Gly5-ol)enkephalin

L-Phenylalaninamide, L-tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-Nα-methyl-

DAMGO, mu opioid receptor agonist

DAMGO, 10 mM in DMSO

78123-71-4

C26H35N5O6

Peptide

Opioid receptor and opioid-like receptor