ChemicalBook > CAS DataBase List > 3-CHLORO-4-(TRIFLUOROMETHOXY)BENZALDEHYDE

3-CHLORO-4-(TRIFLUOROMETHOXY)BENZALDEHYDE

Product Name: 3-CHLORO-4-(TRIFLUOROMETHOXY)BENZALDEHYDE
CAS No.: 83279-38-3
Chemical Name: 3-CHLORO-4-(TRIFLUOROMETHOXY)BENZALDEHYDE
Synonyms: 3-chloro-4-trifluoromethoxybenaldehyde;3-CHLORO-4-(TRIFLUOROMETHOXY)BENZALDEHYDE;Benzaldehyde, 3-chloro-4-(trifluoromethyl)-
CBNumber: CB2461898
Molecular Formula: C8H4ClF3O
Formula Weight: 208.57
MOL File: 83279-38-3.mol

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3-CHLORO-4-(TRIFLUOROMETHOXY)BENZALDEHYDE Property

Boiling point:: 232.9±40.0 °C(Predicted)
Density: 1.42g/ml
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: liquid
color: Clear, colourless
Water Solubility: Insoluble in water.

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
Hazard Note: Irritant
HS Code: 2913000090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC

Product number: C596798
Product name: 3-Chloro-4-(trifluoromethyl)benzaldehyde
Packaging: 50mg
Price: $45
Updated: 2021/12/16

TRC

Product number: C596798
Product name: 3-Chloro-4-(trifluoromethyl)benzaldehyde
Packaging: 500mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC137980
Product name: 3-Chloro-4-(trifluoromethyl)benzaldehyde
Packaging: 1g
Price: $80
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC137980
Product name: 3-Chloro-4-(trifluoromethyl)benzaldehyde
Packaging: 2g
Price: $120
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2815-7-07
Product name: 3-Chloro-4-(trifluoromethyl)benzaldehyde
Packaging: 5G
Price: $149
Updated: 2021/12/16

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3-CHLORO-4-(TRIFLUOROMETHOXY)BENZALDEHYDE Chemical Properties,Usage,Production

Uses

3-Chloro-4-(trifluoromethyl)benzaldehyde is used in synthesis of organic compunds in γ-Aminobutyrate-A Receptor Modulation by 3-Aryl-1-(arylsulfonyl)- 1,4,5,6-tetrahydropyridazines.

Synthesis

1092460-79-1

83279-38-3

The general procedure for the synthesis of 3-chloro-4-trifluoromethylbenzonitrile from 3-chloro-4-trifluoromethylbenzaldehyde was as follows: at 0 °C, using a syringe, diisobutylaluminum hydride (1.0 M toluene solution, 28 mL, 28 mmol) was added slowly and dropwise to 3-chloro-4-(trifluoromethyl)benzonitrile (3.79 g, 18.4 mmol) in tetrahydrofuran (THF, 50 mL ) solution. The reaction mixture was kept at 0 °C for 2 h, followed by warming to room temperature and continued stirring for 2 h. The reaction was carried out on a cooled surface. Upon completion of the reaction, the mixture was cooled to 0 °C and the reaction was quenched with 3M aqueous hydrochloric acid solution (75 mL). The mixture was warmed to room temperature and stirred vigorously for 1.5 hours. Subsequently, the mixture was transferred to a dispensing funnel and diluted with ether (Et2O). The organic phase was separated, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure. Purification by fast chromatography (Analogix? IntelliFlash 280? system, using 15% ethyl acetate/hexane as eluent, SF40-150g column) gave 2.84 g (74% yield) of 3-chloro-4-trifluoromethylbenzaldehyde as a colorless oil. The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 10.09 (s, 1H), 8.21 (s, 1H), 8.12 (d, J = 8.1 Hz, 1H), 8.07-8.02 (m, 1H).

References

[1] Patent: US2009/124666, 2009, A1. Location in patent: Page/Page column 30-32

3-CHLORO-4-(TRIFLUOROMETHOXY)BENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-CHLORO-4-(TRIFLUOROMETHOXY)BENZALDEHYDE Suppliers

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View Lastest Price from 3-CHLORO-4-(TRIFLUOROMETHOXY)BENZALDEHYDE manufacturers

Career Henan Chemical Co

Product: 3-CHLORO-4-(TRIFLUOROMETHOXY)BENZALDEHYDE 83279-38-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 1MT/month
Release date: 2019-07-31

83279-38-3, 3-CHLORO-4-(TRIFLUOROMETHOXY)BENZALDEHYDERelated Search:

3-Chloro-4-(trifluoromethyl)benzaldehyde, JRD, 97% 3-CHLORO-4-(TRIFLUOROMETHOXY)BENZALDEHYDE 3-Chloro-4-(trifluoromethoxy)benzoic acid 4-(Trifluoromethoxy)benzaldehyde 2,6-DICHLORO-4-(TRIFLUOROMETHOXY)BENZALDEHYDE 4-CHLORO-3-(TRIFLUOROMETHOXY)BENZALDEHYDE 3-CHLORO-5-(TRIFLUOROMETHOXY)BENZALDEHYDE TETRACHLORO-4-TRIFLUOROMETHYLBENZOYLFLUORIDE 3-CHLORO-4-(TRIFLUOROMETHOXY)METHYLBENZOATE (3-CHLORO-4-TRIFLUOROMETHOXY-PHENYL)-OXO-ACETONITRILE 3-CHLORO-4-(TRIFLUOROMETHOXY)BENZAMIDE 3-CHLORO-4-(TRIFLUOROMETHYL)BENZOYL FLUORIDE 3,5-DICHLORO-2-HYDROXY-4-(TRIFLUOROMETHYL)BENZOIC ACID 3-CHLORO-4-(TRIFLUOROMETHOXY)BENZOYL CHLORIDE RARECHEM AL BI 0501 3-CHLORO-4-TRIFLUOROMETHYL-BENZOIC ACID 5-CHLORO-2-METHOXY-4-TRIFLUOROMETHYL METHYLCARBOXYLATE

3-CHLORO-4-(TRIFLUOROMETHOXY)BENZALDEHYDE

Benzaldehyde, 3-chloro-4-(trifluoromethyl)-

3-chloro-4-trifluoromethoxybenaldehyde

83279-38-3

Fluorine series

Benzaldehyde