1-NAPHTHOHYDROXAMIC ACID

Product Name: 1-NAPHTHOHYDROXAMIC ACID
CAS No.: 6953-61-3
Chemical Name: 1-NAPHTHOHYDROXAMIC ACID
Synonyms: NSC 57457;Naphthohydroxamicacid;a-Naphthohydroxamic acid;1-NAPHTHOHYDROXAMIC ACID;1-NaphthohydroxamicAcid>alpha-naphthohydroxamicacid;1-NAPHTHOHYDROXAMIC ACID 98+%;HDAC Inhibitor XIX, Compound 2;n-hydroxy-1-naphthalenecarboxamid;1-Naphthalenecarbohydroximic acid
CBNumber: CB2462406
Molecular Formula: C11H9NO2
Formula Weight: 187.19
MOL File: 6953-61-3.mol

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1-NAPHTHOHYDROXAMIC ACID Property

Melting point:: 176-178 °C
Density: 1.291±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: ≥5mg/mL
pka: 8.91±0.30(Predicted)
form: White solid
color: white to tan

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Safety

Risk Statements: 52
WGK Germany: 3
RTECS: QJ1894500
HS Code: 2928009090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 382177
Product name: HDAC Inhibitor XIX, Compound 2
Packaging: 50mg
Price: $110
Updated: 2023/01/07

TCI Chemical

Product number: N0023
Product name: 1-Naphthohydroxamic Acid
Purity: >98.0%(T)
Packaging: 1g
Price: $375
Updated: 2024/03/01

TRC

Product number: N369018
Product name: 1-Naphthohydroxamic Acid
Packaging: 5mg
Price: $55
Updated: 2021/12/16

ChemScene

Product number: CS-0108907
Product name: 1-Naphthohydroxamic Acid
Purity: >98.0%
Packaging: 5mg
Price: $65
Updated: 2021/12/16

ChemScene

Product number: CS-0108907
Product name: 1-Naphthohydroxamic Acid
Purity: >98.0%
Packaging: 10mg
Price: $120
Updated: 2021/12/16

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1-NAPHTHOHYDROXAMIC ACID Chemical Properties,Usage,Production

Uses

1-Naphthohydroxamic Acid is a potent HDAC inhibitor with efficacy against HDAC8, HDAC1 and HDAC6.

Biochem/physiol Actions

1-Naphthohydroxamic Acid is a cell-permeable, potent, and selective histone deacetylase 8 (HDAC8) inhibitor. 1-Naphthohydroxamic acid selectively inhibits HDAC8 (IC50 = 14 μM) over class I HDAC1 and class II HDAC6 (IC50 >100 μM). Treatment of cells with 1-Naphthohydroxamic acid does not increase neither global histone H4 nor tubulin acetylation . Also in contrast to the pan-HDAC inhibitors the compound is not reducing total intracellular HDAC activity.

1-NAPHTHOHYDROXAMIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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1-NAPHTHOHYDROXAMIC ACID Suppliers

Americas 1 CHINA 53 Europe 1 Germany 2 India 2 Japan 1 United Kingdom 4 United States 8 Global 72

J & K SCIENTIFIC LTD.

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Energy Chemical

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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

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TCI Europe

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9ding chemical ( Shanghai) Limited

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6953-61-3, 1-NAPHTHOHYDROXAMIC ACIDRelated Search:

Pyrazine 2-Naphthohydroxamic acid, O-acetate ester Naftalofos N-HYDROXYNAPHTHALIMIDE SODIUM SALT N-Hydroxy-1,8-naphthalimide Naphthaloximidodiethyl thiophosphate N-Hydroxynaphthalimide triflate 1-NAPHTHOHYDROXAMIC ACID

HDAC Inhibitor XIX, Compound 2 - CAS 6953-61-3 - Calbiochem

Naphthalene-1-carbohydroximic acid

N-Hydroxy-1-naphthalenecarboxamide

a-Naphthohydroxamic acid

NSC 57457

HDAC Inhibitor XIX, Compound 2

N-HYDROXYNAPHTHALENE-1-CARBOXAMIDE

alpha-naphthohydroxamicacid

n-hydroxy-1-naphthalenecarboxamid

1-NAPHTHOHYDROXAMIC ACID

Naphthohydroxamicacid

1-NAPHTHOHYDROXAMIC ACID 98+%

1-Naphthalenecarbohydroximic acid

1-NaphthohydroxamicAcid&gt

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1-Naphthalenecarboxamide, N-hydroxy-

6953-61-3

Hydroxylamines

Hydroxylamines (N-Substituted)

Hydroxylamines

Hydroxylamines (N-Substituted)