THEAFLAVIN 3'-O-GALLATE

Product Name: THEAFLAVIN 3'-O-GALLATE
CAS No.: 28543-07-9
Chemical Name: THEAFLAVIN 3'-O-GALLATE
Synonyms: TF-3'-G;Theaflavin 2B;Theaflavin-3’-gallate;THEAFLAVINMONOGALLATEB;Theaflavin-3''-Gallate;THEAFLAVIN 3'-O-GALLATE;3'-O-(3,4,5-Trihydroxybenzoyl);Theaflavin-3'-Gallate (TF-3'-G);THEAFLAVIN 3'-O-GALLATE USP/EP/BP;THEAFLAVIN3GALLATE(3'-ISOMERICFORM)
CBNumber: CB2463115
Molecular Formula: C36H28O16
Formula Weight: 716.6
MOL File: 28543-07-9.mol

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THEAFLAVIN 3'-O-GALLATE Property

Boiling point:: 1226.9±65.0 °C(Predicted)
Density: 1.93
storage temp.: -20°C
solubility: Soluble in ethanol and methan
form: powder
pka: 6.55±0.20(Predicted)
color: Orange-brown
Major Application: food and beverages
InChIKey: GPLOTACQBREROW-WQLSNUALSA-N
SMILES: C(O[C@@H]1CC2=C(O)C=C(O)C=C2O[C@@H]1C1=C2C=C([C@H]3OC4=CC(O)=CC(O)=C4C[C@H]3O)C=C(O)C(=O)C2=C(O)C(O)=C1)(=O)C1=CC(O)=C(O)C(O)=C1

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Safety

WGK Germany: WGK 3
HS Code: 29182900
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL83343
Product name: Theaflavin 3′-gallate
Purity: phyproof Reference Substance
Packaging: 10mg
Price: $424
Updated: 2025/07/31

TRC

Product number: T340220
Product name: Theaflavin-3''-O-gallate
Packaging: 2.5mg
Price: $220
Updated: 2021/12/16

ChemScene

Product number: CS-0008275
Product name: Theaflavin 3-gallate
Purity: 98.68%
Packaging: 5mg
Price: $250
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FT73968
Product name: Theaflavin-3'-gallate (TF-3'-G)
Packaging: 5mg
Price: $325
Updated: 2021/12/16

ChemScene

Product number: CS-0008275
Product name: Theaflavin 3-gallate
Purity: 98.68%
Packaging: 10mg
Price: $420
Updated: 2021/12/16

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THEAFLAVIN 3'-O-GALLATE Chemical Properties,Usage,Production

Chemical Properties

Brown-yellow powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from black tea.

Uses

Theaflavin-3''-O-gallate is a theaflavin found in black tea that has shown to induce apoptosis through promoting mitochondrial dysfunction in human prostate cancer cells.

Synthesis

A method for the preparation of theaflavin-3-gallate, using fresh lychee peel as a source of active polyphenol oxidase, and epigallocatechin gallate (EGCG) and epicatechin (EC) as raw materials for the preparation of theaflavin-3-gallate, which was then purified and separated by large-pore adsorbent resin column chromatography technique to prepare high-purity theaflavin-3-gallate; the method for the first time used the PPO in lychee peel as a catalyst to catalyze the synthesis of theaflavin-3-gallate, and separation and purification to obtain the high purity theaflavin-3-gallate, which solves the catalytic application of PPO in lychee peel in the synthesis of theaflavin-3-gallate, and the method is highly efficient, reproducible and stable. Specifically, it includes the following steps: S1) extraction of lychee polyphenol oxidase: weighing fresh lychee peels, adding buffer, mashing and filtering, retaining the filtrate; adding buffer to the filtrate residue, stirring, filtering, retaining the filtrate; combining the two filtrates, then centrifuging, and taking the supernatant that is the lychee polyphenol oxidase solution; S2) preparation of the crude solution of theaflavin-3-gallate: weighing epigallocatechin gallate (EGCG) and epigallocatechin (EC), add buffer to dissolve fully, then add the lychee polyphenol oxidase solution described in step S1) and hydrogen peroxide solution, stirring reaction, filtration, retention of filtrate, that is, the theaflavin-3-gallate crude solution; S3) theaflavin-3-gallate crude purification: the theaflavin-3-gallate crude solution obtained in step 2) was used as a column chromatograph, and then as a column chromatograph, and then as a column chromatograph. S3) purification of crude theaflavin-3-gallate: the crude solution of the theaflavin-3-gallate obtained in step 2) is gradually added to a column chromatography column equipped with a macroporous adsorbent resin as a column chromatography sampling solution, eluted first with an aqueous solution at the end of the sampling, and then with an alcoholic solution, and the alcoholic eluate is collected, and the alcoholic eluate collected is concentrated under reduced pressure to be free of alcoholic flavor, and freeze-dried, i.e., the theaflavin-3-gallate is obtained.

IC 50

OX: 7.6 μM (IC₅₀)

THEAFLAVIN 3'-O-GALLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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THEAFLAVIN 3'-O-GALLATE Suppliers

China 150 India 1 Japan 1 South Korea 1 United Kingdom 2 United States 9 Global 164

Shanghai Tauto Biotech Co., Ltd.

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Chembest Research Laboratories Limited

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Dalian Meilun Biotech Co., Ltd.

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ShangHai YuanYe Biotechnology Co., Ltd.

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Chengdu Biopurify Phytochemicals Ltd.

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Shanghai Winherb Medical Technology Co., Ltd.

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Beijing HuaMeiHuLiBiological Chemical

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Shanghai Ruji Biology Technology Co., Ltd.

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ProdList: 3224
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View Lastest Price from THEAFLAVIN 3'-O-GALLATE manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Theaflavin-3'-gallate 28543-07-9
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-04-22

Career Henan Chemical Co

Product: Theaflavin 3'-gallate 28543-07-9
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 1000kg
Release date: 2018-12-25

28543-07-9, THEAFLAVIN 3'-O-GALLATERelated Search:

THEAFLAVINE-3,3'-DIGALLATE Naringenin 7-O-β-D-Glucuronide (Mixture of Diastereomers) Epitheaflagallin 3-O-gallate GARDENIN B MEDICAGOL 4',5-DIHYDROXY-7-METHOXYFLAVONE hydroxygenkwanin Quercetin-7-O-β-D-glucopyranoside 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one MOSLOFLAVONE PONCIRIN Theaflavin 3,3′-digallate Naringenin THEAFLAVINE-3-GALLATE Theaflavin THEAFLAVIN 3'-O-GALLATE GALLIC ACID ISOAMYL ESTER 1-Benzosuberone

THEAFLAVIN 3'-O-GALLATE

[(2S,3R)-5,7-dihydroxy-2-[6,8,9-trihydroxy-5-oxo-3-[(2S,3R)-3,5,7-trihydroxychroman-2-yl]-11-bicyclo[5.4.0]undeca-1,3,6,8,10-pentaenyl]chroman-3-yl] 3,4,5-trihydroxybenzoate

THEAFLAVIN3GALLATE(3'-ISOMERICFORM)

THEAFLAVINMONOGALLATEB

Theaflavin-3'-Gallate (TF-3'-G)

3'-O-(3,4,5-Trihydroxybenzoyl)

3,4,5-Trihydroxybenzoic acid (2R,3R)-2-[8-[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-3,4,6-trihydroxy-5-oxo-5H-benzocyclohepten-1-yl]-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester

Theaflavin 2B

TF-3'-G

Benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-2-[8-[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-3,4,6-trihydroxy-5-oxo-5H-benzocyclohepten-1-yl]-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester

THEAFLAVIN 3'-O-GALLATE USP/EP/BP

Theaflavin3'Gallate,inhibit,Inhibitor,Theaflavin 3' Gallate

(2R,3R)-5,7-Dihydroxy-2-(3,4,6-trihydroxy-5-oxo-8-((2R,3R)-3,5,7-trihydroxychroman-2-yl)-5H-benzo[7]annulen-1-yl)chroman-3-yl 3,4,5-trihydroxybenzoate

Theaflavin-3’-gallate

Theaflavin-3''-Gallate

28543-07-9

543-07-9

C36H28O16

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