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MM-589 TFA salt

Product Name
MM-589 TFA salt
CAS No.
2097887-21-1
Chemical Name
MM-589 TFA salt
Synonyms
MM-589 (TFA);MM-589 TFA salt;MM589 TFA,MM 589 TFA
CBNumber
CB24675387
Formula Weight
0
MOL File
Mol file
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MM-589 TFA salt Property

storage temp. 
-20°C, away from moisture
solubility 
DMSO : 25 mg/mL (36.40 mM; ultrasonic and warming and heat to 60°C)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0069689
Product name
MM-589TFA
Purity
98.76%
Packaging
1mg
Price
$1200
Updated
2021/12/16
ChemScene
Product number
CS-0069689
Product name
MM-589TFA
Purity
98.76%
Packaging
2mg
Price
$1800
Updated
2021/12/16
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MM-589 TFA salt Chemical Properties,Usage,Production

Biological Activity

MM-589 TFA is a potent inhibitor of WD repeat domain 5 (WDR5) and mixed lineage leukemia (MLL) protein-protein interactions. MM-MM-589 TFA binds WDR5 with an IC50 of 0.90 nM. IC50 for inhibition of MLL H3K4 methyltransferase activity is 12.7 nM.

in vitro

MM-589 TFA (0.01-10 μM, 4 days or 7 days) potently and selectively inhibits cell growth in human leukemia cell lines harboring MLL translocations.

Cell Viability Assay < table class="zh_use_1"> < tr>

Cell Line: MV4-11 and MOLM-13 cells
Concentration: 0.01, 0.1, 1, 10 μM
Incubation Time: 4 days or 7 days
Result: Potently inhibited MV4-11 and MOLM-13 cell growth with IC 50 s of 0.25 and 0.21 μM, respectively. Had much weaker activity in the inhibition of cell growth of the HL-60 cell line with an IC 50 of 8.6 μM.

target

IC50: 0.90 nM (WDR5), 12.7 nM (HMT)

Ki: <1 nM (WDR5)

MM-589 TFA salt Preparation Products And Raw materials

Raw materials

Preparation Products

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MM-589 TFA salt Suppliers

China 17 United States 2 Global 19
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
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China
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15178
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Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
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China
ProdList
5501
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55
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Fax
0571-87213919
Email
Eric@peptidego.com
Country
China
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7071
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58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
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58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
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China
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11218
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58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
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China
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5132
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Wuxi Helen Biotechnology Co., Ltd.,
Tel
0510-85629785 18013409632
Fax
0510-85625359
Email
sales@reading-chemicals.com
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China
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14081
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ShangHai ChuanQian Chemcial Technique Centre
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15869524721
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3525679403@qq.com
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China
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4343
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cjbscvictory
Tel
13348960310 13348960310
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3003867561@qq.com
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China
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10524
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58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
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China
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29774
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58
TargetMol Chemicals Inc.
Tel
4008200310
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marketing@tsbiochem.com
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China
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24644
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Hangzhou Sinoda Pharmaceutical Technology Co. LTD
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0571-87213919 17306812703
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3007955328@qq.com
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China
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6628
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Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Tel
024-024-88590548 18341751992
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757984502@qq.com
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China
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930
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58
Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd
Tel
13770887460
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wenxi@jszkhy.com
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China
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1352
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Nanjing Shizhou Biology Technology Co.,Ltd
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025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
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China
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Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Tel
+86-18341751992 +86-15382112998
Email
757984502@qq.com
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China
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892
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Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
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Email
info@zzsrm.com
Country
CHINA
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6650
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View Lastest Price from MM-589 TFA salt manufacturers

Wuhan Xinhao Biotechnology Co., Ltd
Product
MM-589 TFA 2097887-21-1
Price
US $2.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
200kg
Release date
2024-01-15

2097887-21-1, MM-589 TFA saltRelated Search:


  • MM-589 TFA salt
  • MM-589 (TFA)
  • MM589 TFA,MM 589 TFA
  • 2097887-21-1