4-(METHYLAMINO)BUTYRIC ACID HYDROCHLORIDE
- Product Name
- 4-(METHYLAMINO)BUTYRIC ACID HYDROCHLORIDE
- CAS No.
- 6976-17-6
- Chemical Name
- 4-(METHYLAMINO)BUTYRIC ACID HYDROCHLORIDE
- Synonyms
- MFCD00044627;4-methylammoniobutyrate;4-methylammoniobutanoate;4-methylazaniumylbutanoate;gamma-N-methylaminobutyrate;4-(Methylamino)butyric acid HCl;4-(Methylamino)butanoic acid HCl;4-(METHYLAMINO)BUTYRIC ACID HYDROCHLORIDE;4-(Methylamino)butyric acid hydrochloride,99%;4-(Methylamino)butyric acid hydrochloride 99%
- CBNumber
- CB2471048
- Molecular Formula
- C5H12ClNO2
- Formula Weight
- 153.61
- MOL File
- 6976-17-6.mol
4-(METHYLAMINO)BUTYRIC ACID HYDROCHLORIDE Property
- Melting point:
- 124-126 °C(lit.)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Sparingly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
- CAS DataBase Reference
- 6976-17-6
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 263710
- Product name
- 4-(Methylamino)butyric acid hydrochloride
- Purity
- 99%
- Packaging
- 25g
- Price
- $102
- Updated
- 2025/07/31
- Product number
- 263710
- Product name
- 4-(Methylamino)butyric acid hydrochloride
- Purity
- 99%
- Packaging
- 100g
- Price
- $250
- Updated
- 2025/07/31
- Product number
- M331983
- Product name
- 4-(Methylamino)butanoicAcidHydrochloride
- Packaging
- 5g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 5494AH
- Product name
- 4-(Methylamino)butyric acid hydrochloride
- Packaging
- 5g
- Price
- $27
- Updated
- 2021/12/16
- Product number
- AS77101-B
- Product name
- 4-(Methylamino)butanoicacidHCl
- Purity
- 95+%
- Packaging
- 100g
- Price
- $203
- Updated
- 2021/12/16
4-(METHYLAMINO)BUTYRIC ACID HYDROCHLORIDE Chemical Properties,Usage,Production
Chemical Properties
white crystalline powder
Uses
4-(Methylamino)butanoic acid Hydrochloride is the salt form of N-Methyl-4-aminobutyric Acid (M285745) which is a GABA derivative and hydrolysis product of the industrial solvent, N-methyl-2-pyrrolidinone. Biologically it is a product of nicotine catabolism in bacteria and inhibits L-Carnitine from undergoing β-oxidation in mammals. It is commonly found in skin products to prevent wrinkles.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
872-50-4
6976-17-6
The general procedure for the synthesis of hydrogen 4-(methylamino)butyrate from N-methylpyrrolidone is as follows: N-methyl-2-pyrrolidone is added to a reaction vessel with concentrated hydrochloric acid. The mixture was placed in an external oil bath, stirred and refluxed at 165 °C for 9 hours, during which time additional additions of concentrated hydrochloric acid were required. Upon completion of the reaction, the hydrochloric acid was removed by distillation under reduced pressure. The remaining solid was dissolved in cold acetone, stirred and cooled until complete crystallization. The resulting white solid was cryoprecipitated, filtered and washed twice with cold acetone and finally dried. The melting point of the product is 119-120°C. The mother liquor was concentrated to recover part of the product with a total yield of 90%.
References
[1] Patent: CN108003044, 2018, A. Location in patent: Paragraph 0009; 0010; 0011
[2] Synthesis, 1981, # 6, p. 468 - 469
[3] Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 3, p. 1376 - 1392
4-(METHYLAMINO)BUTYRIC ACID HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-(METHYLAMINO)BUTYRIC ACID HYDROCHLORIDE manufacturers
- Product
- 4-(METHYLAMINO)BUTYRIC ACID HYDROCHLORIDE 6976-17-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-07-04
- Product
- 4-(METHYLAMINO)BUTYRIC ACID HYDROCHLORIDE 6976-17-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-09