ISOGUVACINE HYDROCHLORIDE
- Product Name
- ISOGUVACINE HYDROCHLORIDE
- CAS No.
- 64603-90-3
- Chemical Name
- ISOGUVACINE HYDROCHLORIDE
- Synonyms
- C13694;isoguvacine;ISOGUVACINE HCL;Isoguvacine hydrochl;ISOGUVACINE HYDROCHLORIDE;1,2,3,6-tetrahydro-4-Pyridinecarboxylic acid;ISOGUVACINE HYDROCHLORIDE ISO 9001:2015 REACH;4-Pyridinecarboxylic acid, 1,2,3,6-tetrahydro-;1,2,3,6-Tetrahydropyridine-4-carboxylic Acid (Isoguvacine);1,2,3,6-TETRAHYDRO-4-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE
- CBNumber
- CB7406481
- Molecular Formula
- C6H9NO2
- Formula Weight
- 127.14
- MOL File
- 64603-90-3.mol
ISOGUVACINE HYDROCHLORIDE Property
- Melting point:
- 220 °C
- Boiling point:
- 280.8±35.0 °C(Predicted)
- Density
- 1.199±0.06 g/cm3(Predicted)
- RTECS
- US5908286
- storage temp.
- Store at RT
- solubility
- H2O: refrigerate if not used immediately.soluble
- form
- solid
- pka
- pK1:9.07 (25°C)
- color
- white
- Water Solubility
- Soluble in water
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- J63243
- Product name
- Isoguvacine hydrochloride, 99%
- Packaging
- 100mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- 0235
- Product name
- Isoguvacine hydrochloride
- Purity
- ≥99%(HPLC)
- Packaging
- 100
- Price
- $223
- Updated
- 2021/12/16
- Product number
- 255530
- Product name
- Isoguvacine hydrochloride
- Packaging
- 100mg
- Price
- $480
- Updated
- 2021/12/16
- Product number
- API0008224
- Product name
- ISOGUVACINE
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $718.41
- Updated
- 2021/12/16
- Product number
- API0008224
- Product name
- ISOGUVACINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1021.65
- Updated
- 2021/12/16
ISOGUVACINE HYDROCHLORIDE Chemical Properties,Usage,Production
Description
This base is isolated, together with Guvacine (q.v.) from the nuts of Areca catechu. It is optically inactive and yields crystalline salts: the hydrochloride, m.p. 231°C; aurich1oride, m.p. 198- 200°C and the p1atinich1oride, m.p. 235°C. The alkaloid is faintly acid to litmus and on methylation gives the N-methyl derivative which, on more vigorous methylation yields the dimethyl compound giving a crystalline platinichloride, m.p. 252°C. The above melting points suggest that the base may be mainly Arecaidine (q.v.) but on distillation with Zn dust, it yields products with the characteristic pyrrole reaction.
Chemical Properties
bp 195-197°C
Uses
A GABAA receptor agonist. Anticonvulsant; antiepileptic.
Definition
ChEBI: Isoguvacine is a tetrahydropyridine.
Biological Activity
Specific GABA A receptor agonist.
References
Jahns., Ber., 21,3404 (1888) Jahns., ibid, 23, 2972 (1890) Jahns., ibid, 24,2615 (1891) Jahns., Arch. Pharrn., 229, 669 (1891) Trier., Zeit. Physiol. Chern., 85,372 (1913)
ISOGUVACINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
ISOGUVACINE HYDROCHLORIDE Suppliers
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