Description References
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Menatetrenone

Description References
Product Name
Menatetrenone
CAS No.
863-61-6
Chemical Name
Menatetrenone
Synonyms
e3100;D00100;Glakay;kaytwo;mk(sub4);k2(sub20);Vitamin K2;MENAQUINONE;Metetrenone;Vitamin MK-4
CBNumber
CB2471321
Molecular Formula
C31H40O2
Formula Weight
444.65
MOL File
863-61-6.mol
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Menatetrenone Property

Melting point:
350C
Boiling point:
494.59°C (rough estimate)
Density 
1.0461 (rough estimate)
refractive index 
1.5045 (estimate)
Flash point:
2℃
storage temp. 
-20°C
form 
neat
InChIKey
DKHGMERMDICWDU-GHDNBGIDSA-N
CAS DataBase Reference
863-61-6(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
RIDADR 
UN 1648 3 / PGII
WGK Germany 
3
RTECS 
QL9279500
HS Code 
2914699000
Toxicity
LD50 intravenous in dog: > 40mL/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
V-031
Product name
Vitamin K2 (MK-4) solution
Purity
100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material
Packaging
031-1ml
Price
$83.6
Updated
2020/08/18
Sigma-Aldrich
Product number
V-031
Product name
Vitamin K2 (MK-4) solution
Purity
100?μg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1 mL
Price
$86.3
Updated
2021/03/22
Sigma-Aldrich
Product number
V9378
Product name
Vitamin K2
Packaging
1g
Price
$330
Updated
2021/03/22
Cayman Chemical
Product number
18423
Product name
Menaquinone 4
Purity
≥98%
Packaging
1g
Price
$256
Updated
2021/03/22
Cayman Chemical
Product number
18423
Product name
Menaquinone 4
Purity
≥98%
Packaging
100mg
Price
$32
Updated
2021/03/22
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Menatetrenone Chemical Properties,Usage,Production

Description

Menatetrenone (also known as MK-4) is a manaquinone compound and a vitamin K compound which can be used as a hemostatic agent as well as adjunctive therapy for the pain of osteoporosis. It mainly takes effects through modulating the signaling of certain tyrosine kinases, thereby affecting several transcription factors including c-myc and c-fos. It is capable of inhibiting tumor cells growth through inducing apoptosis and cell cycle arrest. It can be produced via the conversion of vitamin K1 inside the body including the testes, pancreas and arterial walls.

References

https://pubchem.ncbi.nlm.nih.gov/compound/menatetrenone#section=Biomolecular-Interactions-and-Pathways
https://en.wikipedia.org/wiki/Menatetrenone

Chemical Properties

Yellow Crystals

Uses

Vitamin (prothrombogenic)

Uses

Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a vari ety of physiological processes. Menaquinone 4 has four isoprene residue in its side chain and is also commonly refered to as menatetrenone. Menaquinone-4 is the most common type of vitamin K2 and is k nown as a hemostatic agent and is used as adjunctive therapy for the pain of osteoporosis.

Definition

ChEBI: A menaquinone whose side-chain contains 4 isoprene units in an all-trans-configuration.

Menatetrenone Preparation Products And Raw materials

Raw materials

Preparation Products

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Menatetrenone Suppliers

Wuhan lingjiu Biotechnology Co., Ltd
Tel
Email
llj009bio@163.com
Country
China
ProdList
30
Advantage
58
Shanghai Reson biotech Co., Ltd
Tel
021-56916686
Fax
021-61532877
Email
info@vk-2.com
Country
China
ProdList
63
Advantage
58
Zhengzhou anmousse chemical products co. LTD
Tel
0371-55289822-
Fax
QQ:483339295
Email
483339295@qq.com;
Country
China
ProdList
4883
Advantage
58
Wuhan Dingtong Pharmaceutical Co., Ltd
Tel
027-59207795-
Fax
027-59207795
Email
18327179646@163.com
Country
China
ProdList
1977
Advantage
58
Wellman Pharmaceutical Group Limited
Tel
027-83778875-
Fax
027-83991220
Email
15807197853@163.com
Country
China
ProdList
3559
Advantage
58
Jiangxi ravel Biotechnology Co.,Ltd
Tel
;
Fax
18140514863
Email
bd@ruiweier.cn;lq@ruiweier.cn
Country
China
ProdList
1013
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Mr Qiu:021-50182298(Demestic market) Miss Xu:021-50180596(Abroad market)
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2213
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32358
Advantage
50
Chengdu XiYa Chemical Technology Co., Ltd.
Tel
;
Fax
0539-6365991
Email
sale@xiyashiji.com;3007716753@qq.com
Country
China
ProdList
10578
Advantage
57
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View Lastest Price from Menatetrenone manufacturers

Hebei Lingding Biological Technology Co., Ltd
Product
Menatetrenone 863-61-6
Price
US $289.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
9000kg/per week
Release date
2021-05-12
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Menatetrenone 863-61-6
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
500KGS
Release date
2021-06-15
XI'AN TIANGUANGYUAN BIOTECH CO., LTD.
Product
Vitamin K2 Mk4 ;Vitamin K2;Menatetrenone 863-61-6
Price
US $1000.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
98%
Supply Ability
2500kg/month
Release date
2021-08-09

863-61-6, MenatetrenoneRelated Search:


  • MENATETRENONE
  • MENAQUINONE 4
  • MENAQUINONE
  • 1,4-naphthoquinone,2-methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen
  • 2-methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-1,4-naphthoqu
  • 2-methyl-3-trans-tetraprenyl-1,4-naphthoquinone
  • e3100
  • k2(sub20)
  • menatetranone
  • Menaquinone4, Menatetrenone
  • Menaquinone4, Menatetrenone, VitaminK2
  • 2-Methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl]-1,4-naphthoquinone
  • Menaquinone K4
  • Vitamin MK-4
  • D00100
  • Menatetrenone (jp15/inn)
  • Vitamin K2 (tn)
  • menaquinon-4
  • VITAMIN K2(MENAQUINONE-4)(SH)
  • Vitamin K2(MK-4)
  • Metetrenone
  • Vitamin K2 (MK-4) solution
  • Vitamin K2(20),MK4 0.13%
  • Vitamin K2(20),MK4 1.3% oil
  • Vitamin K2(20),MK4 1.3% powder
  • Vitamin K2(20),MK-4 JP14 powder
  • 2-Methyl-3-geranylgeranyl-1,4-naphthoquinone
  • Glakay
  • Menaquinone 4 (Mixture of cis-trans isoMers)
  • Menatetrenone(11032-49-8)
  • kaytwo
  • menaquinonek(sub4)
  • mk(sub4)
  • vitamink2(sub20)
  • Phytonadione,(Z)
  • MENAQUINONE (K2) 100MG NEAT
  • VitaminK2(20)0.13%Oil
  • VitaminK2(45)98.0%Min.Powder
  • VitaminK2(20)
  • VitaminK2(20)1.3%Powder
  • VitaminK2(20)98.0%Oil
  • VitaminK2(20)98.0%Powder
  • VitaminK2(20)0.13%Powder
  • VitaminK2(20)1.3%Oil
  • (E,E,E)-2-Methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-1,4-naphthalenedione
  • 2-Methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraenyl]naphthalene-1,4-dione
  • Vitamin K2
  • Vitamin K2(20),MK4 0.13% powder
  • Vitamin K2,MK4,menaquinone, menaquinon-4, menatetrenone, menatetren, menatetrenona, menatetrenonum
  • Vitamin K2-Menatetrenone ( MK-4 )
  • Menatetrenone (MK-4)
  • vitamin K2 Menatetrenone
  • Menatetrenone RS
  • Menaquinone-4 Standard
  • 1,4-Naphthalenedione, 2-methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraen-1-yl]-
  • Menatetrenone USP/EP/BP
  • 863-61-6
  • Cofactor