(+/-)-BAY K 8644

ChemicalBook > CAS DataBase List > (+/-)-BAY K 8644

Product Name: (+/-)-BAY K 8644
CAS No.: 93468-89-4
Chemical Name: (+/-)-BAY K 8644
Synonyms: BAY K-8644 (+/-);(+/-)-BAY K 8644;(±)-Bay K 8644 - CAS 93468-89-4 - Calbiochem;(+)-(S)-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)pyridine-5-carboxylic acid;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-[TRIFLUOROMETHYL]PHENYL)PYRIDINE-3-CARBOXYLIC ACID METHYL ESTER;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID, METHYL ESTER;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2'-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID METHYL ESTER
CBNumber: CB2471785
Molecular Formula: C16H15F3N2O4
Formula Weight: 356.3
MOL File: 93468-89-4.mol

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(+/-)-BAY K 8644 Property

Melting point:: 166-172 °C
storage temp.: 2-8°C
solubility: DMSO: 184 mg/mL
form: Yellow solid

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Safety

Hazard Codes: Xi
Risk Statements: 36/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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(+/-)-BAY K 8644 Chemical Properties,Usage,Production

Definition

ChEBI: Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate is a pentasubstituted dihydropyridine carrying methoxycarbonyl, 2-(trifluoromethyl)phenyl and nitro substituents at positions 3, 4 and 5 respectively as well as two methyl substituents at positions 2 and 6. It is a dihydropyridine, a methyl ester, a C-nitro compound and a member of (trifluoromethyl)benzenes.

General Description

Synthetic dihydropyridine derivative that acts as an active Ca²⁺ slow channel agonist in neuroendocrine, muscle, thyroid and other cell types. Prolongs single channel open time without affecting the close time. An L-type Ca²⁺ channel agonist. Composed of two optical isomers. The (-)-enantiomer has strong vasoconstrictive, positive inotropic, and Ca²⁺ agonistic properties, whereas the (+)-enantiomer has weakly vasodilating, negative inotropic, and Ca²⁺ antagonistic properties. The net effect of the racemic mix is that of the negative enantiomer. Promotes β-cell proliferation/regeneration.

Biochem/physiol Actions

Primary TargetL-type Ca2+ channel

(+/-)-BAY K 8644 Preparation Products And Raw materials

Raw materials

Preparation Products

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93468-89-4, (+/-)-BAY K 8644Related Search:

(+/-) CAGED BAY K 8644 R(+)-BAY K 8644, CALCIUM CHANNEL R(+)-BAY K 8644,R(+)-BAY K 8644 CA2(+) CHANNEL BLOCKE,(+/-)-BAY K 8644, 0 TO 5 °C,R(+)-BAY K 8644 98% 0 C S(-)-BAY K 8644,S(-)-BAY K 8644 CA2+ CHANNEL ACTIVATO R(+)-BAY K 8644 CALCIUM CHANNEL (RS)-BAY K 8644,(+/-)-BAY K 8644,BAY K-8644 (+/-),(+/-)-BAY K8644 CALCIUM SLOW CHANNEL (+-)-CAGED BAY K 8644

1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2'-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID METHYL ESTER

1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID, METHYL ESTER

1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-[TRIFLUOROMETHYL]PHENYL)PYRIDINE-3-CARBOXYLIC ACID METHYL ESTER

(+/-)-BAY K 8644

BAY K-8644 (+/-)

(+)-(S)-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)pyridine-5-carboxylic acid

(±)-Bay K 8644 - CAS 93468-89-4 - Calbiochem

93468-89-4

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