PROTX I

Product Name: PROTX I
CAS No.: 484598-35-8
Chemical Name: PROTX I
Synonyms: PROTX I
CBNumber: CB24737414
Molecular Formula: C171H245N53O47S6
Formula Weight: 0
MOL File: Mol file

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PROTX I Property

storage temp.: Store at -20°C
form: Powder
Water Solubility: Soluble to 2 mg/ml in water
Sequence: Glu-Cys-Arg-Tyr-Trp-Leu-Gly-Gly-Cys-Ser-Ala-Gly-Gln-Thr-Cys-Cys-Lys-His-Leu-Val-Cys-Ser-Arg-Arg-His-Gly-Trp-Cys-Val-Trp-Asp-Gly-Thr-Phe-Ser (Disulfide bridge:Cys2-Cys16;Cys9-Cys21;Cys15-Cys28)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 4665
Product name: ProTxI
Packaging: 100U
Price: $204
Updated: 2021/12/16

Usbiological

Product number: 256338
Product name: ProTx I
Packaging: 100ug
Price: $495
Updated: 2021/12/16

ApexBio Technology

Product number: B5676
Product name: ProTxI
Packaging: 100ug
Price: $345
Updated: 2021/12/16

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PROTX I Chemical Properties,Usage,Production

Uses

ProTx-I, a venom toxin of the tarantula Thrixopelma pruriens, is a potent, selective CaV3.1 channel blocker with IC50 values of 0.2 μM and 31.8 μM for hCaV3.1 and hCaV3.2 respectively. ProTx-I is also a potent blocker for voltage-gated Na+ channels and inhibits KV 2.1 channels[1][2].

References

[1] Tsuyako Ohkubo, et al. Tarantula toxin ProTx-I differentiates between human T-type voltage-gated Ca2+ Channels Cav3.1 and Cav3.2. J Pharmacol Sci. 2010;112(4):452-8. DOI:10.1254/jphs.09356fp
[2] Richard E Middleton, et al. Two tarantula peptides inhibit activation of multiple sodium channels. Biochemistry. 2002 Dec 17;41(50):14734-47. DOI:10.1021/bi026546a

PROTX I Preparation Products And Raw materials

Raw materials

Preparation Products

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PROTX I Suppliers

China 29 Japan 1 United Kingdom 1 United States 5 USA 1 Global 37

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View Lastest Price from PROTX I manufacturers

Chengdu Shengnuo Biopharm Co.,Ltd

Product: Palmitoyl Pentapeptide-5 484598-35-8
Price: US $500.00-500.00/kg
Min. Order: 1kg
Purity: ≥99.00%
Supply Ability: 1000000
Release date: 2025-10-10

484598-35-8, PROTX IRelated Search:

PROTX I

484598-35-8

C171H245N53O47S6