AST2818 mesylate

Product Name: AST2818 mesylate
CAS No.: 2130958-55-1
Chemical Name: AST2818 mesylate
Synonyms: Alflutinib mesylate;Furmonertinib;AST2818 mesylate;ASK120067 mesylate;Furmonertinib mesylate;Alflutinib methanesulfonate;Alflutinib mesylate (AST2818);Alflutinib (AST2818 mesylate);Alflutinib mesylate (Furmonertinib);N-(2-((2-(Dimethylamino)ethyl)(methyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acrylamide methanesulfonate
CBNumber: CB24797023
Molecular Formula: C29H35F3N8O5S
Formula Weight: 664.71
MOL File: 2130958-55-1.mol

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AST2818 mesylate Property

storage temp.: Store at -20°C,unstable in solution, ready to use.
solubility: Chloroform: 10 mg/ml; DMF: slightly soluble; DMSO: slightly soluble
form: A crystalline solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0067492
Product name: AST2818mesylate
Purity: 99.99%
Packaging: 5mg
Price: $200
Updated: 2021/12/16

ChemScene

Product number: CS-0067492
Product name: AST2818mesylate
Purity: 99.99%
Packaging: 10mg
Price: $300
Updated: 2021/12/16

ChemScene

Product number: CS-0067492
Product name: AST2818mesylate
Purity: 99.99%
Packaging: 50mg
Price: $850
Updated: 2021/12/16

ChemScene

Product number: CS-0067492
Product name: AST2818mesylate
Purity: 99.99%
Packaging: 100mg
Price: $1250
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573198
Product name: Alflutinib mesylate (AST2818)
Packaging: 100mg
Price: $1283.5
Updated: 2021/12/16

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AST2818 mesylate Chemical Properties,Usage,Production

Description

Furmonertinib (formerly known as alflutinib) is another me-too third-generation EGFR TKI that has a pyridyl ring replacing the phenyl ring of osimertinib and a trifluoroethyl group replacing the methyl group (Fig. 4). This TKI, which was discovered and developed by Shanghai Allist Pharma, was approved in November 2019 by the NMPA of China for the second-line treatment of NSCLC with EGFR sensitive mutation and EGFR T790M drug-resistant mutation, and more recently as a first-line treatment for classical EGFR mutant NSCLC. In June 2022, furmonertinib was granted the Fast Track designation by the FDA in patients with advanced or metastatic NSCLC with activating EGFR or HER2 mutations, including exon 20 insertion mutations.

AST2818 mesylate Preparation Products And Raw materials

Raw materials

Preparation Products

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AST2818 mesylate Suppliers

China 42 United States 5 Global 47

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
Country: China
ProdList: 1925
Advantage: 55

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7887
Advantage: 56

Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

Tel: 21-57721279
Fax: QQ：14057904
Email: sales@shydchem.com.cn
Country: China
ProdList: 990
Advantage: 56

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9458
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4573
Advantage: 55

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-66023220 0086-15250997978
Fax: 025-58362220
Email: 1511893459@qq.com
Country: China
ProdList: 7892
Advantage: 55

Shanghai Rechem science Co., Ltd.

Tel: 21-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2992
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
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Shanghai Rlavie Technology Co., Ltd.

Tel: 21-67759270 17717059219
Fax: QQ：1479352695
Email: sales@rlavie.com
Country: China
ProdList: 1107
Advantage: 55

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

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View Lastest Price from AST2818 mesylate manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: AST2818 mesylate 2130958-55-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-26

2130958-55-1, AST2818 mesylateRelated Search:

AST2818 mesylate

Alflutinib mesylate (AST2818)

Alflutinib methanesulfonate

Alflutinib mesylate

N-[2-[[2-(Dimethylamino)ethyl]methylamino]-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-2-propenamide compd. with methanesulfonate (1:1)

Alflutinib (AST2818 mesylate)

Alflutinib mesylate (Furmonertinib)

Furmonertinib mesylate

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N-(2-((2-(Dimethylamino)ethyl)(methyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acrylamide methanesulfonate

ASK120067 mesylate

Furmonertinib

2130958-55-1