(S)-5-tert-butoxy-4-(3-((S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic acid

Uses

Product Name: (S)-5-tert-butoxy-4-(3-((S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic acid
CAS No.: 1026987-94-9
Chemical Name: (S)-5-tert-butoxy-4-(3-((S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic acid
Synonyms: DUPA(OtBu)3-OH;DUPA(OtBu)-OH, 10 mM in DMSO;Inhibitor,DUPA(OtBu)-OH,DUPA(OtBu)OH,DUPA(OtBu) OH,inhibit;2-[3-(1,3-bis-tert-butoxycarbonylpropyl)ureido]pentanedioic acid 1-tert-butyl ester;(S)-5-tert-butoxy-4-(3-((S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic acid;(R)-5-(tert-butoxy)-4-(3-((S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic acid;L-Glutamic acid, N-[[[(1S)-3-carboxy-1-[(1,1-dimethylethoxy)carbonyl]propyl]amino]carbonyl]-, 1,5-bis(1,1-dimethylethyl) ester
CBNumber: CB24803911
Molecular Formula: C23H40N2O9
Formula Weight: 488.57
MOL File: 1026987-94-9.mol

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(S)-5-tert-butoxy-4-(3-((S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic acid Property

Melting point:: 120-123°C
Boiling point:: 627.6±55.0 °C(Predicted)
Density: 1.139±0.06 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: Chloroform (Sparingly), Methanol (Slightly)
form: Solid
pka: 4.46±0.10(Predicted)
color: White to Off-White
InChIKey: KBDDHSXZOLZZGF-GJZGRUSLSA-N
SMILES: C(OC(C)(C)C)(=O)[C@H](CCC(OC(C)(C)C)=O)NC(N[C@H](C(OC(C)(C)C)=O)CCC(O)=O)=O

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: T205165
Product name: (S)-5-tert-Butoxy-4-(3-((s)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoicAcid
Packaging: 10mg
Price: $75
Updated: 2021/12/16

Crysdot

Product number: CD21019583
Product name: (S)-5-tert-butoxy-4-(3-((S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoicacid
Purity: 95+%
Packaging: 10mg
Price: $415
Updated: 2021/12/16

Crysdot

Product number: CD21019583
Product name: (S)-5-tert-butoxy-4-(3-((S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoicacid
Purity: 95+%
Packaging: 50mg
Price: $875
Updated: 2021/12/16

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(S)-5-tert-butoxy-4-(3-((S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic acid Chemical Properties,Usage,Production

Uses

(S)-5-tert-Butoxy-4-(3-((s)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic Acid is used as a reactant in the synthesis of a DUPA-paclitaxel conjugate for antigen targeted therapy of prostate cancer.

Uses

(S)-5-tert-Butoxy-4-(3-((s)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic Acid is used as a reactant in the synthesis of a DUPA-paclitaxel conjugate for antigen targeted therapy of prostate cancer.

in vivo

DUPA-targeted Docetaxel (DTX) conjugate with longer spacer has no toxicity in major organs of treated mice^[3].

(S)-5-tert-butoxy-4-(3-((S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-5-tert-butoxy-4-(3-((S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic acid Suppliers

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1026987-94-9, (S)-5-tert-butoxy-4-(3-((S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic acidRelated Search:

2-(4-((9S,13S)-9,13-Bis(Tert-Butoxycarbonyl)-18,18-Dimethyl-3,11,16-Trioxo-17-Oxa-2,4,10,12-Tetraazanonadecyl)Phenyl)Acetic Acid PSMA-11 tert-Butyl-DCL (PSMA inhibitor) Vipivotide tetraxetan Linker L-Glutamic acid, N-[[[(1S)-1-carboxy-5-[[(6-fluoro-3-pyridinyl)carbonyl]amino]pentyl]amino]carbonyl]-

(S)-5-tert-butoxy-4-(3-((S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic acid

2-[3-(1,3-bis-tert-butoxycarbonylpropyl)ureido]pentanedioic acid 1-tert-butyl ester

(R)-5-(tert-butoxy)-4-(3-((S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl)ureido)-5-oxopentanoic acid

Inhibitor,DUPA(OtBu)-OH,DUPA(OtBu)OH,DUPA(OtBu) OH,inhibit

L-Glutamic acid, N-[[[(1S)-3-carboxy-1-[(1,1-dimethylethoxy)carbonyl]propyl]amino]carbonyl]-, 1,5-bis(1,1-dimethylethyl) ester

DUPA(OtBu)3-OH

DUPA(OtBu)-OH, 10 mM in DMSO

1026987-94-9