Vipivotide tetraxetan Linker
- Product Name
- Vipivotide tetraxetan Linker
- CAS No.
- 1703768-74-4
- Chemical Name
- Vipivotide tetraxetan Linker
- Synonyms
- JUN68744;PSMA-617 Linker;Vipivotide tetraxetan Linker;H2N-TranexamicAcid-2Nal-PSMA-OH;VIPIVOTIDE TETRAXETAN LINKER;PSMA-617 LINKER;Vipivotide tetraxetan Ligand-Linker Conjugate;Vipivotide tetraxetan Linker( 1703768-74-4),PSMA-617 linker;L-Lysine, N6-[N-[[trans-4-(aminomethyl)cyclohexyl]carbonyl]-3-(2-naphthalenyl)-L-alanyl]-N2-[[[(1S)-1,3-dicarboxypropyl]amino]carbonyl]-;(((S)-5-((S)-2-(trans-4-(Aminomethyl)cyclohexane-1-carboxamido)-3-(naphthalen-2-yl)propanamido)-1-carboxypentyl)carbamoyl)-L-glutamic acid;(2S)-2-[[(1S)-5-[[(2S)-2-[[4-(aminomethyl)cyclohexanecarbonyl]amino]-3-(2-naphthyl)propanoyl]amino]-1-carboxy-pentyl]carbamoylamino]pentanedioic acid
- CBNumber
- CB65821123
- Molecular Formula
- C33H45N5O9
- Formula Weight
- 655.74
- MOL File
- 1703768-74-4.mol
Vipivotide tetraxetan Linker Property
- Boiling point:
- 1063.2±65.0 °C(Predicted)
- Density
- 1.303±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. -20°C
- pka
- 3.78±0.10(Predicted)
- form
- Solid
- color
- White to off-white
- InChIKey
- JHWCOTSIOATVKA-UIGMUVSQSA-N
- SMILES
- C(O)(=O)[C@H](CCCCNC(=O)[C@H](CC1=CC=C2C(=C1)C=CC=C2)NC([C@@H]1CC[C@@H](CN)CC1)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-0095890
- Product name
- VipivotidetetraxetanLinker
- Purity
- 99.88%
- Packaging
- 50mg
- Price
- $2000
- Updated
- 2021/12/16
Vipivotide tetraxetan Linker Chemical Properties,Usage,Production
Uses
Vipivotide tetraxetan Ligand-Linker Conjugate (PSMA-617 Ligand-Linker Conjugate) is a complex composed of pharmacophore group Glutamate-urea-Lysine peptide coupling linker, which can be used to synthesize Vipivotide tetraxetan (PSMA-617). Glutamate-urea-Lysine selectively binds to prostate-specific membrane antigen (PSMA)[1].
IC 50
Non-cleavable Linker
References
[1] Beneová M, et al. Albumin-Binding PSMA Ligands: Optimization of the Tissue Distribution Profile. Mol Pharm. 2018 Mar 5;15(3):934-946. DOI:10.1021/acs.molpharmaceut.7b00877
Vipivotide tetraxetan Linker Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Vipivotide tetraxetan Linker manufacturers
- Product
- Vipivotide tetraxetan Linker 1703768-74-4
- Price
- US $0.00/mg
- Min. Order
- 50mg
- Purity
- >95.00%
- Supply Ability
- 50mg
- Release date
- 2024-04-01