ChemicalBook > CAS DataBase List > Z-DEVD-AFC

Z-DEVD-AFC

Product Name: Z-DEVD-AFC
CAS No.: 1135416-11-3
Chemical Name: Z-DEVD-AFC
Synonyms: Z-DEVD-AFC;Z-ASP-GLU-VAL-ASP-AFC;CASPASE-3, SUBSTRATE IV;Z-ASP-GLU-VAL-ASP-AFC: Z-DEVD-AFC;CASPASE-3, SUBSTRATE, FLUOROGENIC;CASPASE-3 SUBSTRATE IV, FLUOROGENIC;CASPASE-3, SUBSTRATE IV ;Z-ASP-GLU-VAL-ASP-AFC;7-AMINO-4-TRIFLUOROMETHYLCOUMARIN, N-CBZ-L-ASPARTYL-L-GLUTAMYL-L-VALYL-L-ASPARTIC ACID AMIDE;(5S,8S,11S,14S)-8-(2-carboxyethyl)-5-(carboxymethyl)-11-isopropyl-3,6,9,12-tetraoxo-14-((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)carbamoyl)-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oicacid;(4S)-5-[[(2S)-1-[[(2S)-3-carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-[[(2S)-3-carboxy-2-(phenylmethoxycarbonylamino)propanoyl]amino]-5-oxopentanoic acid
CBNumber: CB2482912
Molecular Formula: C36H38F3N5O14
Formula Weight: 821.71
MOL File: Mol file

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Z-DEVD-AFC Property

storage temp.: -20°C
solubility: Formic Acid: 1 mg/ml
form: A lyophilized powder
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 24564
Product name: Z-DEVD-AFC
Purity: ≥95%
Packaging: 1mg
Price: $116
Updated: 2024/03/01

AK Scientific

Product number: 2779DC
Product name: (4S)-5-[[(2S)-1-[[(2S)-3-Carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-[[(2S)-3-carboxy-2-(phenylmethoxycarbonylamino)propanoyl]amino]-5-oxopentanoicacid
Packaging: 1mg
Price: $226
Updated: 2021/12/16

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Z-DEVD-AFC Chemical Properties,Usage,Production

Uses

Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity[1].

References

[1] Santiago AR, et al. High glucose induces caspase-independent cell death in retinal neural cells. Neurobiol Dis. 2007;25(3):464-472. DOI:10.1016/j.nbd.2006.10.023

Z-DEVD-AFC Preparation Products And Raw materials

Raw materials

Preparation Products

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1135416-11-3, Z-DEVD-AFCRelated Search:

Z-DEVD-FMK AFC

CASPASE-3, SUBSTRATE IV

CASPASE-3 SUBSTRATE IV, FLUOROGENIC

CASPASE-3, SUBSTRATE, FLUOROGENIC

7-AMINO-4-TRIFLUOROMETHYLCOUMARIN, N-CBZ-L-ASPARTYL-L-GLUTAMYL-L-VALYL-L-ASPARTIC ACID AMIDE

Z-DEVD-AFC

Z-ASP-GLU-VAL-ASP-AFC

Z-ASP-GLU-VAL-ASP-AFC: Z-DEVD-AFC

CASPASE-3, SUBSTRATE IV ;Z-ASP-GLU-VAL-ASP-AFC

(5S,8S,11S,14S)-8-(2-carboxyethyl)-5-(carboxymethyl)-11-isopropyl-3,6,9,12-tetraoxo-14-((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)carbamoyl)-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oicacid

(4S)-5-[[(2S)-1-[[(2S)-3-carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-[[(2S)-3-carboxy-2-(phenylmethoxycarbonylamino)propanoyl]amino]-5-oxopentanoic acid

1135416-11-3

C36H38F3N5O14

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