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Sitagliptin Impurity 12

Product Name
Sitagliptin Impurity 12
CAS No.
1803026-54-1
Chemical Name
Sitagliptin Impurity 12
Synonyms
(Z)-1-(3-(trifluoromethyl);Sitagliptin EP Impurity 12;(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1;2-Buten-1-one, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (2Z)-;(Z)-1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one (Sitagliptin Impurity)
CBNumber
CB24842022
Molecular Formula
C16H12F6N4O
Formula Weight
390.28
MOL File
1803026-54-1.mol
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Sitagliptin Impurity 12 Property

Boiling point:
517.5±60.0 °C(Predicted)
Density 
1.52±0.1 g/cm3(Predicted)
solubility 
soluble in Chloroform, DCM, Methanol
pka
-0.06±0.20(Predicted)
form 
Oil
color 
Light Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D450690
Product name
(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one
Packaging
10mg
Price
$140
Updated
2021/12/16
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Sitagliptin Impurity 12 Chemical Properties,Usage,Production

Uses

(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985),an impurity of Sitagliptin (S491000). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

Sitagliptin Impurity 12 Preparation Products And Raw materials

Raw materials

Preparation Products

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Sitagliptin Impurity 12 Suppliers

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