ChemicalBook > CAS DataBase List > Sitagliptin Impurity 12
Sitagliptin Impurity 12
- Product Name
- Sitagliptin Impurity 12
- CAS No.
- 1803026-54-1
- Chemical Name
- Sitagliptin Impurity 12
- Synonyms
- (Z)-1-(3-(trifluoromethyl);Sitagliptin EP Impurity 12;(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1;2-Buten-1-one, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (2Z)-;(Z)-1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one (Sitagliptin Impurity)
- CBNumber
- CB24842022
- Molecular Formula
- C16H12F6N4O
- Formula Weight
- 390.28
- MOL File
- 1803026-54-1.mol
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Sitagliptin Impurity 12 Property
- Boiling point:
- 517.5±60.0 °C(Predicted)
- Density
- 1.52±0.1 g/cm3(Predicted)
- solubility
- soluble in Chloroform, DCM, Methanol
- pka
- -0.06±0.20(Predicted)
- form
- Oil
- color
- Light Yellow
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N-Bromosuccinimide Price
TRC
- Product number
- D450690
- Product name
- (2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one
- Packaging
- 10mg
- Price
- $140
- Updated
- 2021/12/16
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Sitagliptin Impurity 12 Chemical Properties,Usage,Production
Uses
(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985),an impurity of Sitagliptin (S491000). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
Sitagliptin Impurity 12 Preparation Products And Raw materials
Raw materials
Preparation Products
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1803026-54-1, Sitagliptin Impurity 12Related Search:
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Sitagliptin impurity 5
Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate
ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate
2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE
Sitagliptin Impurity 34
2,4,5-TRIFLUOROBENZYL CHLORIDE
(R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate
Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,Methylester,(bR)-
Sitagliptin
Sitagliptin Impurity 14
Sitagliptin Defuoro IMpurity 5
Sitagliptin DeaMino IMpurity 1
(S)-Sitagliptin Phosphate
2,2,2-TRIFLUORO-N'-(TRIFLUOROACETYL)ACETOHYDRAZIDE
(R)-10-(2,4,5-trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione