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PI3K/mTOR Inhibitor-2

Product Name
PI3K/mTOR Inhibitor-2
CAS No.
1848242-58-9
Chemical Name
PI3K/mTOR Inhibitor-2
Synonyms
PI3K/mTOR Inhibitor-2;PI3K/mTOR Inhibitor-2 ，E2375;PI3K/mTOR Inhibitor-2, 10 mM in DMSO;N-(5-(3-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide;Benzenesulfonamide, N-[5-(3-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-2-methoxy-3-pyridinyl]-2,4-difluoro-;PI3K,inhibit,PI3K/mTOR Inhibitor-2,Inhibitor,mTOR,PI-3K/mTOR Inhibitor-2,PI3K/mTOR Inhibitor2,PI3K/mTOR Inhibitor 2,Mammalian target of Rapamycin,Phosphoinositide 3-kinase
CBNumber
CB24845043
Molecular Formula
C20H13ClF2N4O4S
Formula Weight
478.86
MOL File
1848242-58-9.mol
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PI3K/mTOR Inhibitor-2 Property

Boiling point:
609.4±65.0 °C(Predicted)
Density 
1.57±0.1 g/cm3(Predicted)
pka
6.38±0.40(Predicted)
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0042282
Product name
PI3K/mTORInhibitor-2
Purity
99.45%
Packaging
5mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0042282
Product name
PI3K/mTORInhibitor-2
Purity
99.45%
Packaging
10mg
Price
$550
Updated
2021/12/16
ChemScene
Product number
CS-0042282
Product name
PI3K/mTORInhibitor-2
Purity
99.45%
Packaging
50mg
Price
$1650
Updated
2021/12/16
ChemScene
Product number
CS-0042282
Product name
PI3K/mTORInhibitor-2
Purity
99.45%
Packaging
100mg
Price
$2250
Updated
2021/12/16
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PI3K/mTOR Inhibitor-2 Chemical Properties,Usage,Production

Uses

PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor with IC50s of 3.4/34/16/1 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ and 4.7 nM for mTOR[1]. Antitumor activity[1].

IC 50

PI3Kα: 3.4 nM (IC50); PI3Kβ: 34 nM (IC50); PI3Kδ: 16 nM (IC50); PI3Kγ: 1 nM (IC50); mTOR: 4.7 nM (IC50)

References

[1] Yu T, et al. Discovery of Pyridopyrimidinones as Potent and Orally Active Dual Inhibitors of PI3K/mTOR. ACS Med Chem Lett. 2018 Feb 27;9(3):256-261. DOI:10.1021/acsmedchemlett.8b00002

PI3K/mTOR Inhibitor-2 Preparation Products And Raw materials

Raw materials

Preparation Products

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PI3K/mTOR Inhibitor-2 Suppliers

China 29 United States 3 Global 32
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
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China
ProdList
7778
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Shanghai Beckham Medical Technology Co., Ltd
Tel
13816613772
Fax
QQ: 12922499
Email
huahero21@sina.com
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China
ProdList
2391
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55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
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58
Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
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China
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71826
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Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
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China
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8011
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55
ShangHai Biochempartner Co.,Ltd
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177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8000
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Shanghai Anyinuo Biomedical Technology Co., Ltd.
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021-34625901 18018851262;
Email
420970979@qq.com
Country
China
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5894
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58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
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United States
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32435
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InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
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sales@invivochem.cn
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United States
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6391
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Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
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58

1848242-58-9, PI3K/mTOR Inhibitor-2Related Search:


  • PI3K/mTOR Inhibitor-2
  • Benzenesulfonamide, N-[5-(3-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-2-methoxy-3-pyridinyl]-2,4-difluoro-
  • PI3K,inhibit,PI3K/mTOR Inhibitor-2,Inhibitor,mTOR,PI-3K/mTOR Inhibitor-2,PI3K/mTOR Inhibitor2,PI3K/mTOR Inhibitor 2,Mammalian target of Rapamycin,Phosphoinositide 3-kinase
  • N-(5-(3-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-7-yl)-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide
  • PI3K/mTOR Inhibitor-2, 10 mM in DMSO
  • PI3K/mTOR Inhibitor-2 ，E2375
  • 1848242-58-9
  • C20H13ClF2N4O4S