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RANATENSIN

Product Name
RANATENSIN
CAS No.
29451-71-6
Chemical Name
RANATENSIN
Synonyms
RANATENSIN;Ranatensin (8CI,9CI);RANATENSIN USP/EP/BP;Ranatensin, ≥95% (HPLC);PYR-VAL-PRO-GLN-TRP-ALA-VAL-GLY-HIS-PHE-MET-NH2;GLP-VAL-PRO-GLN-TRP-ALA-VAL-GLY-HIS-PHE-MET-NH2;PGLU-VAL-PRO-GLN-TRP-ALA-VAL-GLY-HIS-PHE-MET-NH2;PYROGLU-VAL-PRO-GLN-TRP-ALA-VAL-GLY-HIS-PHE-MET-NH2;5-Oxo-L-Pro-L-Val-L-Pro-L-Glu(NH2)-L-Trp-L-Ala-L-Val-Gly-L-His-L-Phe-L-Met-NH2;L-Methioninamide, 5-oxo-L-prolyl-L-valyl-L-prolyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-L-phenylalanyl-
CBNumber
CB2486293
Molecular Formula
C61H84N16O13S
Formula Weight
1281.48
MOL File
29451-71-6.mol
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RANATENSIN Property

Boiling point:
1790.5±65.0 °C(Predicted)
Density 
1.326±0.06 g/cm3(Predicted)
storage temp. 
−20°C
pka
13.08±0.46(Predicted)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
R1072-25
Product name
Ranatensin
Packaging
1mg
Price
$531
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0003026
Product name
RANATENSIN
Purity
95.00%
Packaging
1MG
Price
$152.25
Updated
2021/12/16
Biorbyt Ltd
Product number
orb372782
Product name
Ranatensin
Purity
> 95%
Packaging
1mg
Price
$287.3
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0003026
Product name
RANATENSIN
Purity
95.00%
Packaging
5MG
Price
$743.25
Updated
2021/12/16
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RANATENSIN Chemical Properties,Usage,Production

Uses

Ranatensin is a undecapeptide and a Bombesin Receptor angonist, can be isolated from amphibian skin, such as the frog, Rana pipiens. Ranatensin could maintain the dynamic balance of animal blood pressure, without cross-tachyphylaxis with Angiotensin amide (HY-P2212), Bradykinin.html" class="link-product" target="_blank">Bradykinin (HY-P0206), or Norepinephrine.html" class="link-product" target="_blank">Norepinephrine (HY-13715)[1][2].

in vivo

Ranatensin (10-50 μg/mL, 0.1-1 mL; i.v.; single dose) increases blood pressure in the dog and rabbit, indicating a direct peripheral vasoconstrictor action[2].
Ranatensin (10-50 μg/mL, 0.1-1 mL; i.v.; single dose) also lowers blood pressure in the monkey, being as potent as Eledoisin.html" class="link-product" target="_blank">Eledoisin (HY-P0006). It show a direct peripheral action on vascular smooth muscle[2].
Ranatensin (10-50 μg/mL, 0.005-0.1 mL; i.v.; single dose) has a variable effect based on the basal level of blood pressure in the rat that shows antihypertensive efffect during high level and raises blood pressure when level is low, in part due to the release of noradrenaline from peripheral sympathetic nerve endings[2].

References

[1] Jensen RT, et al. A synthetic peptide that is a bombesin receptor antagonist. Nature. 1984 May 3-9;309(5963):61-3. DOI:10.1038/309061a0
[2] Geller RG, et al. The action of ranatensin, a new polypeptide from amphibian skin, on the blood pressure of experimental animals. Br J Pharmacol. 1970 Dec;40(4):605-16. DOI:10.1111/j.1476-5381.1970.tb10641.x

RANATENSIN Preparation Products And Raw materials

Raw materials

Preparation Products

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RANATENSIN Suppliers

GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
7247
Advantage
62
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
6295
Advantage
60
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
6687
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Chengdu Huachun Technology Co., Ltd
Tel
400-1166-196 15982826727
Fax
QQ:800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
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View Lastest Price from RANATENSIN manufacturers

Career Henan Chemical Co
Product
RANATENSIN 29451-71-6
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2020-03-05

29451-71-6, RANATENSINRelated Search:


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  • RANATENSIN
  • PGLU-VAL-PRO-GLN-TRP-ALA-VAL-GLY-HIS-PHE-MET-NH2
  • GLP-VAL-PRO-GLN-TRP-ALA-VAL-GLY-HIS-PHE-MET-NH2
  • 5-Oxo-L-Pro-L-Val-L-Pro-L-Glu(NH2)-L-Trp-L-Ala-L-Val-Gly-L-His-L-Phe-L-Met-NH2
  • Ranatensin (8CI,9CI)
  • PYROGLU-VAL-PRO-GLN-TRP-ALA-VAL-GLY-HIS-PHE-MET-NH2
  • RANATENSIN USP/EP/BP
  • L-Methioninamide, 5-oxo-L-prolyl-L-valyl-L-prolyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-L-phenylalanyl-
  • 29451-71-6
  • C61H84N16O13S1
  • C61H85N16O13S
  • C61H84N16O13S
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