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Thymopentin

Product Name
Thymopentin
CAS No.
69558-55-0
Chemical Name
Thymopentin
Synonyms
TP-5;RKDVY;Immunox;Timunox;ORF-15244;Thyopentin;THYMOPETIN;THYMOPENTIN;Thymopentine;ThymopentinⅡ
CBNumber
CB7491069
Molecular Formula
C30H49N9O9
Formula Weight
679.77
MOL File
69558-55-0.mol
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Thymopentin Property

Density 
1.44±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 10 mg/ml
pka
3.07±0.10(Predicted)
form 
Powder
color 
White
CAS DataBase Reference
69558-55-0(CAS DataBase Reference)
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Safety

WGK Germany 
3
HS Code 
3504009000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T8806
Product name
Thymopentin
Purity
≥97% (HPLC)
Packaging
10mg
Price
$235
Updated
2024/03/01
Alfa Aesar
Product number
J61431
Product name
Thymopentin
Purity
99+%
Packaging
25mg
Price
$117
Updated
2023/06/20
Alfa Aesar
Product number
J61431
Product name
Thymopentin
Purity
99+%
Packaging
100mg
Price
$257
Updated
2021/12/16
Cayman Chemical
Product number
30119
Product name
Thymopentin
Packaging
5mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
30119
Product name
Thymopentin
Packaging
10mg
Price
$62
Updated
2024/03/01
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Thymopentin Chemical Properties,Usage,Production

Description

Thymopentin is a kind of peptide. Peptides and polypeptides play a critical role in the immune system and are therefore predestined as a source for new approaches in immunotherapy. Thymopentin is capable of modulating the immune response. It is a fragment of the thymopoietins (TMPOs) which is a family of nuclear protein. Studies have shown that Thymopentin is capable of affecting the function of T cells and monocytes monitored by increased cGMP level and the triggering of cellular signaling. It is also capable of improve an imbalanced immune system. As an immunomodulating agent, it is clinically used in the treatment of autoimmune diseases such as atopic dermatitis, chronic lymphocytic leukemia, Sezary’s syndrome, rheumatoid arthritis and decreased immune competency. Recent study has also shown that its immuno-modulating effect can also help fight against the infection of mycobacterium tuberculosis.

Originator

Janssen (Belgium)

Uses

Thymopentin Acetate (TP-5) is a synthetic immunomodulating pentapeptide.

Uses

immunoregulator

Definition

ChEBI: Thymopentin is an oligopeptide.

brand name

SINTOMODULINA; TIMUNOX

Clinical Use

Thymopentin is a synthetic, immunomodulating pentapeptide, representing the active fragment of the thymus hormone, thymopoietin. Thymopentin induces phenotypic differentiation and maturation of T-cells. It appears of value in the treatment of primary immune deficiency, rheumatoid arthritis, atopic dermatitis, sarcoidosis and a variety of other diseases with manifestations of disturbed immune balance.

References

Zhang, Yan, et al. "Novel thymopentin release systems prepared from bioresorbable PLA–PEG–PLA hydrogels." International journal of pharmaceutics 386.1 (2010): 15-22.
Gonser, S., E. Weber, and G. Folkers. "Peptides and polypeptides as modulators of the immune response: thymopentin—an example with unknown mode of action." Pharmaceutica Acta Helvetiae 73.6 (1999): 265-273.
Wang, Ying, et al. "Synthetic modifications of the immunomodulating peptide thymopentin to confer anti-mycobacterial activity." Biomaterials 35.9 (2014): 3102-3109.

Thymopentin Preparation Products And Raw materials

Raw materials

Preparation Products

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Thymopentin Suppliers

ZHEJLANG HUADI PHARMACEUTICAL GROUP CO, LTD.
Tel
0571-81061160 18268059989
Email
3343284820@qq.com
Country
China
ProdList
55
Advantage
58
Hubei xinghengkang Chemical Technology Co., Ltd
Tel
027-88878869 18162384755
Email
969094702@qq.com
Country
China
ProdList
59
Advantage
58
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8844
Advantage
52
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
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View Lastest Price from Thymopentin manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Thymopentin 69558-55-0
Price
US $0.00/g
Min. Order
1g
Purity
98%min
Supply Ability
1000g
Release date
2023-01-11
Sinoway Industrial co., ltd.
Product
Thymopentin 69558-55-0
Price
US $0.00/KG
Min. Order
2KG
Purity
99% up
Supply Ability
20tons
Release date
2022-08-24
Wuhan Haorong Biotechnology Co.,Ltd
Product
Pentapeptide-1 69558-55-0
Price
US $1.00/G
Min. Order
1G
Purity
99%
Supply Ability
10000KG
Release date
2024-07-10

69558-55-0, ThymopentinRelated Search:


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