GLP-1 (7-37)

Product Name: GLP-1 (7-37)
CAS No.: 106612-94-6
Chemical Name: GLP-1 (7-37)
Synonyms: Tglp-1;GLP-1, 7-37;HuMan GLP-1;Glp-I (7-37);insulinotropin;GLP-1(7-37), >98%;Human GLP-1 (7-37);GLP-1 acetate salt;GLP-1 (7-37) (HUMAN);GLP-1(7-37) impurity
CBNumber: CB1445727
Molecular Formula: C151H228N40O47
Formula Weight: 3355.67
MOL File: 106612-94-6.mol

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GLP-1 (7-37) Property

Density: 1.48±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: Water:30.0(Max Conc. mg/mL);8.34(Max Conc. mM)
form: Lyophilized powder
color: White to off-white
Water Solubility: Soluble in water at 2mg/ml
Sequence: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH
CAS DataBase Reference: 106612-94-6

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Safety

Safety Statements: 22-24/25
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G9416
Product name: Glucagon-Like Peptide 1 Fragment 7-37 human
Purity: ≥96% (HPLC)
Packaging: 0.5mg
Price: $530
Updated: 2024/03/01

Alfa Aesar

Product number: J66232
Product name: Glucagon Like Peptide-1 (7-37)
Packaging: 0.5mg
Price: $191
Updated: 2023/06/20

Alfa Aesar

Product number: J66232
Product name: Glucagon Like Peptide-1 (7-37)
Packaging: 1mg
Price: $364
Updated: 2023/06/20

Tocris

Product number: 5374
Product name: GLP-1(7-37)
Packaging: 1
Price: $458
Updated: 2021/12/16

ChemScene

Product number: CS-5975
Product name: GLP-1(7-37)
Purity: 99.87%
Packaging: 1mg
Price: $252
Updated: 2021/12/16

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GLP-1 (7-37) Chemical Properties,Usage,Production

Description

GLP-1 (7-37) is an endogenous truncated form of GLP-1 that arises from proglucagon processing in intestinal endocrine L cells, GLP-1 (7-37) acts as a GLP-1 receptor agonist and is an insulinotropic hormone that augments glucose induced insulin secretion. GLP-1 (7-37) and derivatives GLP-1 (9-37) and GLP-1 (28-37) can reduce plaque inflammation and increase phenotypic characteristics of plaque stability in a murine model of atherosclerosis.

Uses

Glucagon-Like Peptide 1 Fragment 7-37 human has been used:

as a positive control for insulin secretion of pancreatic islets
to test its effect on insulin response in horse islets
in combination with mesenchymal stem cells (MSCs) test its protective effects in myocardial infarction

General Description

Glucagon-Like Peptide 1 Fragment 7-37 human (GLP-1-(7-37)) is an amino-truncated form of GLP-1.

Biochem/physiol Actions

Glucagon-Like Peptide 1 Fragment 7-37 human (GLP-1-(7-37)) interacts with the GLP-1 receptor (GLP-1r). It mediates insulin release by stimulating the cyclic AMP accumulation in islet cells GLP-l(7-37) is a potential therapeutic agent due to its insulin-secretagogue functionality.

in vitro

In vitro, truncated glucagon-like peptides [GLP-1(7-36)-amide and GLP-1(7-37)] increase insulin secretion in a glucose-dependent manner, and desensitization to the action of GLP-1(7-37) has been demonstrated acutely with high concentrations.

in vivo

GLP-1(7-37) (0.5, 5 or 50 pmol/min/kg) infused during the second hour of a 2-hour 11-mM hyperglycemic clamp produces a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion in rats. Infusion of GLP-1(7-37) (5 pmol/min/kg) from 1 hour through 7 hours produces a sustained increase in plasma insulin concentration relative to levels in rats infused with vehicle in rats with maintained glucose concentration at 11 mM.

storage

Store at -20°C

GLP-1 (7-37) Preparation Products And Raw materials

Raw materials

Preparation Products

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GLP-1 (7-37) Suppliers

China 166 France 1 Germany 2 Japan 1 Switzerland 1 United Kingdom 1 United States 16 Global 188

Minglong (Xianning) Pharmaceutical Co., LTD

Tel: 155-7155-6913 15571556913
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Hubei Wanye Zhongcheng Chemical Reagent Co., Ltd.

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Alabiochem Tech.Co., Ltd.

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Shanghai Hanhong Scientific Co.,Ltd.

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Chemsky（shanghai）International Co.,Ltd.

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Cellmano Biotech Limited

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Hangzhou Sage Chemical Co., Ltd.

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Beijing HuaMeiHuLiBiological Chemical

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MedChemexpress LLC

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TargetMol Chemicals Inc.

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Fax: 021-33632979
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View Lastest Price from GLP-1 (7-37) manufacturers

Wuhan Senwayer Century Chemical Co.,Ltd

Product: GLP-1(7-37) 106612-94-6
Price: US $0.00/mg
Min. Order: 10mg
Purity: 99%
Supply Ability: 1000 boxes
Release date: 2023-06-27

Zibo Hangyu Biotechnology Development Co., Ltd

Product: GLP-1 (7-37) 106612-94-6
Price: US $80.00-800.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-11-02

Shanghai Getian Industrial Co., LTD

Product: GLP-1 (7-37) 106612-94-6
Price: US $28.00/box
Min. Order: 1box
Purity: 99%
Supply Ability: 20000box
Release date: 2024-06-03

106612-94-6, GLP-1 (7-37)Related Search:

Growth hormone releasing peptide Pralmorelin Sermorelin Nesiritide acetate Thymopentin Triptorelin acetate Pramlintide acetate Eptifibatide Thymalfasin Glucagon GLUCAGON-LIKE PEPTIDE I FRAGMENT 7-36 AMIDE HUMAN GLP-2（Glucagon-like peptide-2） GLP-1（Glucagon-like peptide-1）(7-36) GLP-1 (7-37) GLP-1 (9-36) AMIDE (HUMAN, BOVINE, GUINEA PIG, MOUSE, PORCINE, RAT) AC-LEU-VAL-LYS-ALDEHYDE GLP-1+ FITC（Glucagon-like peptide-1）(7-36) ([125I]-TYR)-GLP-1 (7-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)

Insulinotropin (human)

Peptide GLP-1 (human glucose-lowering peptide-1)

Glp-I (7-37)

Glucagon like peptide I (7-37)

Glucagon-related peptide (oncorhynchus kisutch), 3-L-glutamic acid-6-L-phenylalanine-9-L-aspartic acid-12-L-serine-15-L-glutamic acid-16-glycine-21-L-isoleucine-24-L-alanine-27-L-valine-28-L-lysine-31-glycine-

Tglp-1

GLP-1, 7-37

Preproglucagon 78-108

GLP-1 (7-37) (huMan, bovine, guinea pig, Mouse, rat) Proglucagon (78-108) (huMan, bovine, guinea pig, Mouse, rat), Insulinotropin (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (7-37) (huMan, bovine, guinea pig, Mouse, rat), Preproglucag

7-37-Glucagon-like peptide I (human)

Human GLP-1 (7-37)

GLP-1(7-38), Insulinotropin

insulinotropin

GLP-1, 7-37, Preproglucagon 78-108

Glucagon-Like Peptide (GLP) I (7-37)

Proglucagon (78-108) (huMan, bovine, guinea pig, Mouse, rat), Insulinotropin (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (7-37) (huMan, bovine, guinea pig, Mouse, rat), Preproglucagon (98-128) (huMan, bovine, guinea pig, Mouse, rat)

Proglucagon (78-108) (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (7-37) (huMan, bovine, guinea pig, Mouse, rat), Insulinotropin (huMan, bovine, guinea pig, Mouse, rat), Preproglucagon (98-128) (huMan, bovine, guinea pig, Mouse, rat)

HuMan GLP-1

7-37-Glucagon-likepeptide

H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH acetate salt

GLP-1 (7-37) Acetate | Glucagon-Like Peptide 1

l-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alany

PROGLUCAGON (78-108) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)

PREPROGLUCAGON 78-108 HUMAN

PREPROGLUCAGON (98-128) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)

INSULINOTROPIN (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)

HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY

H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH

HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG

GLP-1 (HUMAN, 7-37) (BOVINE, CANINE, RAT, GUINEA PIG)

GLP-1 (7-37) (HUMAN)

GLP-1 (7-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)

GLUCAGON-LIKE PEPTIDE 1 (HUMAN, 7-37) (BOVINE, CANINE, RAT, GUINEA PIG)

GLUCAGON LIKE PEPTIDE-I (7-37), HUMAN

GLUCAGON-LIKE PEPTIDE 1, FRAGMENT 7-37 HUMAN

GLUCAGON-LIKE PEPTIDE 1 (7-37)

GLUCAGON-LIKE PEPTIDE 1 (7-37) (HUMAN)

GLUCAGON-LIKE PEPTIDE 1 (7-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)

GLP-1(7-37), >98%

GLP-1(7-37),HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG, >98%

GLP-1(7-37) impurity

H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH USP/EP/BP

H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GL...

TIANFUCHEM--106612-94-6---H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH

H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR- LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-LE-ALA-TRP-LEU-VAL- LYS-GLY-ARG-GLY-OH

H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH

Insulinotropin acetate [GLP-1 (7-37)

GLP-1 acetate salt

Glucagon-Like Peptide-1 (7-37)|GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat)

(5S,11S,14S,17S,20S,23S,26S,29S,32S,35S,38S,41S,44S,50S,53S,56S,59S,62S,65S,68S,71S,74S,77S,80S,86S)-20-((1H-Indol-3-yl)methyl)-86-((S)-2-((S)-2-amino-3-(1H-imidazol-5-yl)propanamido)propanamido)-44-(3-amino-3-oxopropyl)-11,35-bis(4-aminobutyl)-29,77-dibenzyl-26-((S)-sec-butyl)-32,50-bis(2-carboxyethyl)-68-(carboxymethyl)-5-(3-guanidinopropyl)-56-(4-hydroxybenzyl)-74,80-bis((R)-1-hydroxyethyl)-59,62,71-tris(hydroxymethyl)-17,53-diisobutyl-14,65-diisopropyl-23,38,41-trimethyl-4,7,10,13,16,19,22,2

106612-94-6

C151H228N40O47

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