DL-PENICILLAMINE

Application in Rheumatic Arthritis

Product Name: DL-PENICILLAMINE
CAS No.: 52-66-4
Chemical Name: DL-PENICILLAMINE
Synonyms: DL-PEN;dl-valin;NSC 22880;NSC 44656;D,L-Pen-OH;H-DL-Pen-OH;AKOS NCG1-0051;DL-PENCILLAMINE;b-Mercaptovaline;DL-PENICILLAMINE
CBNumber: CB2488772
Molecular Formula: C5H11NO2S
Formula Weight: 149.21
MOL File: 52-66-4.mol

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DL-PENICILLAMINE Property

Melting point:: 204-208 °C(lit.)
Boiling point:: 251.8±35.0℃ (760 Torr)
Density: 1.204±0.06 g/cm3 (20 ºC 760 Torr)
refractive index: 1.5216 (estimate)
Flash point:: 106.1±25.9℃
storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: Methanol (Slightly), Water (Soluble)
pka: pK: 1.8 (carboxyl); 7.9 (a-amino); 10.5 (b-thiol)
form: solid
Water Solubility: Soluble in ethanol, hot water and sodium hydroxide.
Merck: 14,7088
BRN: 2039817
CAS DataBase Reference: 52-66-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38-40-20/21/22
Safety Statements: 26-36-22
WGK Germany: 3
RTECS: YV9445000
HS Code: 29309099
Toxicity: LD50 orally in rats: 365 mg/kg (Jaffe)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: P0025
Product name: DL-Penicillamine
Purity: >98.0%(T)
Packaging: 1g
Price: $71
Updated: 2021/12/16

Alfa Aesar

Product number: B24710
Product name: DL-Penicillamine, 97+%
Packaging: 1g
Price: $30.65
Updated: 2024/03/01

Alfa Aesar

Product number: B24710
Product name: DL-Penicillamine, 97+%
Packaging: 5g
Price: $85.1
Updated: 2024/03/01

Alfa Aesar

Product number: B24710
Product name: DL-Penicillamine
Purity: 97+%
Packaging: 25g
Price: $281
Updated: 2023/06/20

TRC

Product number: P223010
Product name: DL-Penicillamine
Packaging: 1g
Price: $85
Updated: 2021/12/16

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DL-PENICILLAMINE Chemical Properties,Usage,Production

Application in Rheumatic Arthritis

Penicillamine onset may be seen in 1 to 3 months, and most responses occur within 6 months. Early adverse effects include skin rash, metallic taste, hypogeusia, stomatitis, anorexia, nausea, vomiting, and dyspepsia. Glomerulonephritis may occur, which manifests as proteinuria and hematuria. Penicillamine is usually reserved for patients who are resistant to other therapies because of the rare but potentially serious induction of autoimmune diseases (e.g., Goodpasture’s syndrome, myasthenia gravis).

Chemical Properties

white to almost white crystalline powder

Uses

antirheumatic, chelating agent (copper), Wilson's desease treatment

Uses

DL-Penicillamine is a penicillin metabolite used in the treatment of Wilson’s disease, Cystinuria, Scleroderma and arsenic poisoning.

Definition

ChEBI: An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Safety Profile

Poison by ingestion and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.

DL-PENICILLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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DL-PENICILLAMINE Suppliers

Belgium 1 China 117 Europe 2 Germany 5 India 9 Japan 2 Switzerland 2 United Kingdom 10 United States 21 USA 1 Global 170

Nanjing Quantong Pharmaceutical Technology Co., Ltd

Tel: 13062552990; 13062552990
Email: sales@aldone.com.cn
Country: China
ProdList: 118
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
Email: info@hanhongsci.com
Country: China
ProdList: 42982
Advantage: 64

Shanghai G&K Biomedical Scientific Inc.

Tel: 021-34502253 13391330186
Fax: +86-21-23027826
Email: info@gksci.com
Country: China
ProdList: 134
Advantage: 52

BEST-REAGENT

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11726
Advantage: 57

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View Lastest Price from DL-PENICILLAMINE manufacturers

PNP Biotech Co. Ltd

Product: L-(+)-Penicillamine 52-66-4
Price: US $0.00/KG
Min. Order: 25KG
Purity: 98%
Supply Ability: Inquiry
Release date: 2022-09-29

Career Henan Chemical Co

Product: DL-PENICILLAMINE 52-66-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98-99.9%
Supply Ability: 100kg
Release date: 2020-02-04

52-66-4, DL-PENICILLAMINERelated Search:

Ampicillin DL-4-Chlorophenylalanine DL-4-Cyanophenylalanine 2-AMINO-3-(3-METHOXY-PHENYL)-PROPIONIC ACID 2-Bromo-DL-Phenylalanine DL-3-(4-Fluorophenyl)alanine Mecillinam 6-Aminopenicillanic acid D-Penicillamine Dicloxacillin sodium DL-PENICILLAMINE Penicillin G potassium salt N-Acetyl-DL-penicillamine hemihydarate,N-ACETYL-DL-PENICILLAMINE 98%,N-ACETYL-DL-PENICILLAMINE,ACETYL-DL-PENICILLAMINE, N- Mezlocillin D-PENICILLAMINE DISULFIDE OXACILLIN SODIUM Cloxacillin-13C4 SodiuM Salt S-Benzyl-DL-Penicillamine

3-mercapto-dl-valin

3-mercapto-dl-valine

dl-3-mercaptovaline

dl-valin

3,3-Dimethyl-DL-cysteine~3-Mercapto-DL-valine

DL-PENICILLAMINE, 99+%

DL-PENICILLAMINE, 98+%

AKOS NCG1-0051

DL-BETA-MERCAPTOVALINE

DL-BETA,BETA-DIMETHYLCYSTEINE

PENICILLAMINE(DL-)

3,3-DIMENTHYL-DL-CYSTEINE

β,β-dimethyl-dl-cysteine

DL-PENCILLAMINE

Valine, 3-mercapto, DL.

2-Amino-3-mercapto-3-methylbutyric acid

b,b-Dimethylcysteine

b-Mercaptovaline

Cysteine, 3,3-dimethyl-

DL-b-Mercaptovaline

DL-Valine, 3-mercapto-

NSC 22880

NSC 44656

Valine, 3-mercapto- (9CI)

Valine, 3-mercapto-, DL- (8CI)

β,β-Dimethyl-DL-cysteine, DL-2-Amino-3-mercapto-3-methylbutanoic acid

(±)-3,3-Dimethylcysteine

(±)-3-Mercaptovaline

β-Mercapto-DL-valine

DL-PenicillaMine, 97+%

DL-beta,beta-Dimethylcysteine DL-beta-Mercaptovaline

D-PENICILLAMINE DL

BETA-MERCAPTO-DL-VALINE

BETA, BETA-DIMETHYL-DL-CYSTEINE

DL-2-AMINO-3-MERCAPTO-3-METHYLBUTANOIC ACID

DL-PENICILLAMINE

DL-β-Mercaptovaline

3,3-DIMETHYL-DL-CYSTEINE

DL-Penicillamine&gt

Valine, 3-mercapto-

DL-Penicillajnine

D,L-Pen-OH

H-DL-Pen-OH

DL-PEN

DL- Penicillamine racemic

52-66-4

CH32CSHCHNH2COOH

AMINE

Radiopharmaceutical Chemistry (Chelating Reagents)

Ligands for Pharmaceutical Research

Specialty Synthesis

Unnatural Amino Acid Derivatives

Peptide Synthesis

Amino Acids

Antibiotics

Analytical Chemistry

Biochemistry

Ligands for Pharmaceutical Research