3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine

Product Name: 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine
CAS No.: 1679330-37-0
Chemical Name: 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine
Synonyms: AZ Dyrk1B 33;AZ-Dyrk1B-33, 10 mM in DMSO;1-Benzyl-3-(2-methylpyrimidin-4-yl)-1H-pyrrolo[2,3-c];3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2;1-Benzyl-3-(2-methylpyrimidin-4-yl)-1H-pyrrolo[2,3-c]pyridine;3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine;1H-Pyrrolo[2,3-c]pyridine, 3-(2-methyl-4-pyrimidinyl)-1-(phenylmethyl)-;Dual specificity tyrosine regulated kinase,kinase,syndrome,mechanism,cells,resistance,stress,inhibit,Inhibitor,metabolic,response,undergoing,DYRK,Mirk-related,AZDyrk1B33,Minibrain-related,Dyrk1B,AZ Dyrk1B 33,Dual specificity tyrosine phosphorylation regulated kinase,AZ-Dyrk-1B-33,osteosarcoma
CBNumber: CB24902771
Molecular Formula: C19H16N4
Formula Weight: 300.36
MOL File: 1679330-37-0.mol

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3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine Property

Boiling point:: 541.2±50.0 °C(Predicted)
Density: 1.20±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 6.79±0.30(Predicted)
form: Solid
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Tocris

Product number: 5632
Product name: AZDyrk1B33
Purity: ≥98%(HPLC)
Packaging: 10
Price: $296
Updated: 2021/12/16

TRC

Product number: M337923
Product name: 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine
Packaging: 2.5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0065849
Product name: AZ-Dyrk1B-33
Purity: ≥99.0%
Packaging: 5mg
Price: $480
Updated: 2021/12/16

ChemScene

Product number: CS-0065849
Product name: AZ-Dyrk1B-33
Purity: ≥99.0%
Packaging: 1mg
Price: $180
Updated: 2021/12/16

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3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine Chemical Properties,Usage,Production

Uses

4,6-Bis(4-fluorophenyl)-2-methyl-5-(4-pyridyl)-2H-pyrazolo[3,4-b]pyridine is a potential Dyrk1B kinase inhibitor and used to investigate resistance mechanism related to stress response in cells.

Biological Activity

Potent and selective Dyrk1B kinase inhibitor th at increased the number of incretin-expressing cells in diabetic mice.
AZ Dyrk1B 33 is a potent and selective Dyrk1B kinase (dual-specificity tyrosine phosphorylation-regulated kinase 1B) inhibitor. AZ Dyrk1B 33 potently increases the numbers of neurogenin 3-expressing enteroendocrine progenitors, Gip-expressing K-cells, and Glp-1-expressing L-cells in zebrafish and diabetic mice. It decreases glucose levels in both larval and juvenile zebrafish.

storage

Store at +4°C

3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine Suppliers

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1679330-37-0, 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridineRelated Search:

3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine

AZ Dyrk1B 33

1H-Pyrrolo[2,3-c]pyridine, 3-(2-methyl-4-pyrimidinyl)-1-(phenylmethyl)-

3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2

Dual specificity tyrosine regulated kinase,kinase,syndrome,mechanism,cells,resistance,stress,inhibit,Inhibitor,metabolic,response,undergoing,DYRK,Mirk-related,AZDyrk1B33,Minibrain-related,Dyrk1B,AZ Dyrk1B 33,Dual specificity tyrosine phosphorylation regulated kinase,AZ-Dyrk-1B-33,osteosarcoma

1-Benzyl-3-(2-methylpyrimidin-4-yl)-1H-pyrrolo[2,3-c]pyridine

1-Benzyl-3-(2-methylpyrimidin-4-yl)-1H-pyrrolo[2,3-c]

AZ-Dyrk1B-33, 10 mM in DMSO

1679330-37-0