3-METHOXY-5-NITROBENZOIC ACID
- Product Name
- 3-METHOXY-5-NITROBENZOIC ACID
- CAS No.
- 78238-12-7
- Chemical Name
- 3-METHOXY-5-NITROBENZOIC ACID
- Synonyms
- 3-Methoxy-5-nitrobenzoicaci;3-METHOXY-5-NITROBENZOIC ACID;Benzoic acid, 3-methoxy-5-nitro-;3-METHOXY-5-NITROBENZOIC ACID ISO 9001：2015 REACH
- CBNumber
- CB2492546
- Molecular Formula
- C8H7NO5
- Formula Weight
- 197.14
- MOL File
- 78238-12-7.mol
3-METHOXY-5-NITROBENZOIC ACID Property
- Melting point:
- 186-189 °C
- Boiling point:
- 389.5±27.0 °C(Predicted)
- Density
- 1.430±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 3.36±0.10(Predicted)
- Appearance
- Light yellow to yellow Solid
- InChI
- InChI=1S/C8H7NO5/c1-14-7-3-5(8(10)11)2-6(4-7)9(12)13/h2-4H,1H3,(H,10,11)
- InChIKey
- QXIIPLXNJAJOMR-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC([N+]([O-])=O)=CC(OC)=C1
Safety
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M326943
- Product name
- 3-Methoxy-5-nitrobenzoicacid
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CS-W005811
- Product name
- 3-Methoxy-5-nitrobenzoicacid
- Packaging
- 5g
- Price
- $125
- Updated
- 2021/12/16
- Product number
- CS-W005811
- Product name
- 3-Methoxy-5-nitrobenzoicacid
- Packaging
- 10g
- Price
- $201
- Updated
- 2021/12/16
- Product number
- 076277
- Product name
- 3-Methoxy-5-nitrobenzoic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $416
- Updated
- 2021/12/16
- Product number
- CS-W005811
- Product name
- 3-Methoxy-5-nitrobenzoicacid
- Packaging
- 25g
- Price
- $474
- Updated
- 2021/12/16
3-METHOXY-5-NITROBENZOIC ACID Chemical Properties,Usage,Production
Synthesis
99-34-3
865-34-9
78238-12-7
3,5-Dinitrobenzoic acid (5.0 g, 23.57 mmol) was added to a mixed solution of lithium methanolate (LiOMe, 3.6 g, 94.28 mmol) and hexamethylphosphorotriamine (HMPA, 100.0 mL) at room temperature. The reaction mixture was stirred at room temperature for 17 hours before being warmed to 80 °C to continue the reaction for 17 hours. Upon completion of the reaction, the mixture was cooled to room temperature and poured into a mixture of 6 M sulfuric acid (H2SO4) and ice water. Extraction was carried out with ether (Et2O) and the organic phase was washed sequentially with 1N hydrochloric acid (HCl) and saturated brine and dried over anhydrous sodium sulfate (Na2SO4). The organic phase was concentrated under reduced pressure to give a yellow solid 3-methoxy-5-nitrobenzoic acid (4.0 g, 86% yield). The product was characterized by 1H-NMR (300 MHz, DMSO-d6): δ13.76 (brs, 1H), 8.21 (m, 1H), 7.95 (t, 1H, J=2.7Hz), 7.82 (dd, 1H, J=2.7,1.1Hz), 3.94 (s, 3H).
References
[1] Organic Letters, 2009, vol. 11, # 4, p. 791 - 794
[2] Journal of the American Chemical Society, 2005, vol. 127, # 32, p. 11202 - 11203
[3] Patent: WO2014/196793, 2014, A1. Location in patent: Page/Page column 73; 74
[4] Synthesis (Germany), 2016, vol. 48, # 19, p. 3263 - 3271
[5] Patent: EP2364983, 2011, A2. Location in patent: Page/Page column 65
3-METHOXY-5-NITROBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-METHOXY-5-NITROBENZOIC ACID manufacturers
- Product
- 3-METHOXY-5-NITROBENZOIC ACID 78238-12-7
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-26
- Product
- 3-methoxy-5-nitrobenzoic acid 78238-12-7
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100 tons
- Release date
- 2020-01-10
- Product
- 3-METHOXY-5-NITROBENZOIC ACID 78238-12-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-02