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CK2 INHIBITOR II

Product Name
CK2 INHIBITOR II
CAS No.
749234-11-5
Chemical Name
CK2 INHIBITOR II
Synonyms
DMAT >=98% (HPLC);DMAT(CK2 Inhibitor);inhibit,Casein Kinase,DMAT,Inhibitor;CASEIN KINASE II INHIBITOR;CK2 INHIBITOR;2-Dimethylamino-4,5,6,7-tetrabromobenzimidazole;4,5,6,7-tetrabromo-N,N-dimethyl-1H-benzimidazol-2-amine;1H-Benzimidazol-2-amine, 4,5,6,7-tetrabromo-N,N-dimethyl-;4,5,6,7-tetrabroMo-N,N-diMethyl-1H-benzo[d]iMidazol-2-aMine
CBNumber
CB2497369
Molecular Formula
C9H7Br4N3
Formula Weight
476.79
MOL File
749234-11-5.mol
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CK2 INHIBITOR II Property

Melting point:
>330℃ (Decomposition)
Boiling point:
497.7±55.0 °C(Predicted)
Density 
2.410±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
≥23.85 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form 
solid
pka
4.55±0.30(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2044
Product name
DMAT
Purity
≥98% (HPLC)
Packaging
5MG
Price
$76.2
Updated
2023/06/20
Sigma-Aldrich
Product number
SML2044
Product name
DMAT
Purity
≥98% (HPLC)
Packaging
25MG
Price
$309
Updated
2023/06/20
Cayman Chemical
Product number
21182
Product name
DMAT
Purity
≥98%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
21182
Product name
DMAT
Purity
≥98%
Packaging
5mg
Price
$161
Updated
2024/03/01
Cayman Chemical
Product number
21182
Product name
DMAT
Purity
≥98%
Packaging
10mg
Price
$283
Updated
2024/03/01
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CK2 INHIBITOR II Chemical Properties,Usage,Production

Description

DMAT is a cell-permeable inhibitor of casein kinase 2 (CK2; IC50 = 0.13 μM). It also inhibits Pim-1, Pim-3, HIPK2, and HIPK3 (IC50s = 0.15, 0.097, 0.37, and 0.59 μM, respectively). DMAT blocks cell growth and induces cell death in cancer cells, both in culture and in mouse xenografts.

Uses

2-Dimethylamino-4,5,6,7-tetrabromobenzimidazole is a novel powerful and selective inhibitor of protein kinase CK2.

CK2 INHIBITOR II Preparation Products And Raw materials

Raw materials

Preparation Products

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749234-11-5, CK2 INHIBITOR IIRelated Search:

N,N-Dimethylaniline

  • DMAT(CK2 Inhibitor)
  • CASEIN KINASE II INHIBITOR;CK2 INHIBITOR
  • 4,5,6,7-tetrabroMo-N,N-diMethyl-1H-benzo[d]iMidazol-2-aMine
  • 2-Dimethylamino-4,5,6,7-tetrabromobenzimidazole
  • 4,5,6,7-tetrabromo-N,N-dimethyl-1H-benzimidazol-2-amine
  • 1H-Benzimidazol-2-amine, 4,5,6,7-tetrabromo-N,N-dimethyl-
  • DMAT >=98% (HPLC)
  • inhibit,Casein Kinase,DMAT,Inhibitor
  • 749234-11-5
  • C9H7Br4N3
  • Akt
  • mTOR
  • PI3K