CK2 INHIBITOR II
- Product Name
- CK2 INHIBITOR II
- CAS No.
- 749234-11-5
- Chemical Name
- CK2 INHIBITOR II
- Synonyms
- DMAT >=98% (HPLC);DMAT(CK2 Inhibitor);inhibit,Casein Kinase,DMAT,Inhibitor;CASEIN KINASE II INHIBITOR;CK2 INHIBITOR;2-Dimethylamino-4,5,6,7-tetrabromobenzimidazole;4,5,6,7-tetrabromo-N,N-dimethyl-1H-benzimidazol-2-amine;1H-Benzimidazol-2-amine, 4,5,6,7-tetrabromo-N,N-dimethyl-;4,5,6,7-tetrabroMo-N,N-diMethyl-1H-benzo[d]iMidazol-2-aMine
- CBNumber
- CB2497369
- Molecular Formula
- C9H7Br4N3
- Formula Weight
- 476.79
- MOL File
- 749234-11-5.mol
CK2 INHIBITOR II Property
- Melting point:
- >330℃ (Decomposition)
- Boiling point:
- 497.7±55.0 °C(Predicted)
- Density
- 2.410±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- ≥23.85 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
- form
- solid
- pka
- 4.55±0.30(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML2044
- Product name
- DMAT
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $76.2
- Updated
- 2023/06/20
- Product number
- SML2044
- Product name
- DMAT
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $309
- Updated
- 2023/06/20
- Product number
- 21182
- Product name
- DMAT
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 21182
- Product name
- DMAT
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $161
- Updated
- 2024/03/01
- Product number
- 21182
- Product name
- DMAT
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $283
- Updated
- 2024/03/01
CK2 INHIBITOR II Chemical Properties,Usage,Production
Description
DMAT is a cell-permeable inhibitor of casein kinase 2 (CK2; IC50 = 0.13 μM). It also inhibits Pim-1, Pim-3, HIPK2, and HIPK3 (IC50s = 0.15, 0.097, 0.37, and 0.59 μM, respectively). DMAT blocks cell growth and induces cell death in cancer cells, both in culture and in mouse xenografts.
Uses
2-Dimethylamino-4,5,6,7-tetrabromobenzimidazole is a novel powerful and selective inhibitor of protein kinase CK2.