ISOPROPYLMAGNESIUM CHLORIDE LITHIUM CHL& Property

Boiling point:

66℃

Density 

0.951 g/mL at 25 °C

Flash point:

-17 °C

solubility 

Miscible with ethers and amines.

Sensitive 

Air & Moisture Sensitive

Safety

Hazard Codes 

F,C

Risk Statements 

14/15-19-34-11

Safety Statements 

16-26-29-33-36/37/39-43-45-8

RIDADR 

UN 3399 4.3/PG 2

HazardClass 

4.3

HS Code 

29319090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Hazard statements

H225Highly Flammable liquid and vapour

H261In contact with water releases flammable gas

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

H333May be harmful if inhaled

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P223Keep away from any possible contact with water, because of violent reaction and possible flash fire.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

ISOPROPYLMAGNESIUM CHLORIDE LITHIUM CHL& Chemical Properties,Usage,Production

Uses

Isopropylmagnesium chloride is used in the regioselective functionalization of trisubstituted pyridines, electrophilic amination for preparation of amines and functionalization of cyclopentene derivatives. It is involved in the preparation of 2,3-functionalized furans, benzofurans, and thiophenes. Further, it is used in benzylic Grignards via sulfur-magnesium exchange.