Uses
ChemicalBook > CAS DataBase List > 3,6-DIOXAOCTANEDIOIC ACID

3,6-DIOXAOCTANEDIOIC ACID

Uses
Product Name
3,6-DIOXAOCTANEDIOIC ACID
CAS No.
23243-68-7
Chemical Name
3,6-DIOXAOCTANEDIOIC ACID
Synonyms
DOODA;PEG2-(CH2CO2H)2;3,6-Dioxasuberic acid;HOOCCH2O-PEG1-CH2COOH;3, 6-dioxyoctaneic acid;3,6-dioxoctanedioic acid;3,6-Dioxaoctandioic acid;3,6-Dioxaoctanedioic acid CAS;(Ethylenebisoxy)diacetic acid;1,2-Bis(carboxymethoxy)ethane
CBNumber
CB2499237
Molecular Formula
C6H10O6
Formula Weight
178.14
MOL File
23243-68-7.mol
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3,6-DIOXAOCTANEDIOIC ACID Property

Melting point:
68-71℃
Boiling point:
429.2±25.0 °C(Predicted)
Density 
1.375
vapor pressure 
0Pa at 20℃
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
3.09±0.10(Predicted)
form 
solid
color 
White to off-white
LogP
-2.29 at 25℃
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45-27-22
RIDADR 
3261
HazardClass 
8
PackingGroup 
III
HS Code 
2917198090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

TRC
Product number
D486153
Product name
3,6-DioxaoctanedioicAcid
Packaging
500mg
Price
$110
Updated
2021/12/16
Iris Biotech GmbH
Product number
PEG2035
Product name
DOODA
Packaging
5G
Price
$270
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD154915
Product name
3,6-Dioxaoctanedioic acid
Packaging
5G
Price
$270
Updated
2021/12/16
Apolloscientific
Product number
OR19555
Product name
3,6-Dioxaoctanedioicacid
Packaging
1g
Price
$44
Updated
2021/12/16
SynQuest Laboratories
Product number
2121-1-37
Product name
3,6-Dioxaoctanedioic acid
Packaging
1g
Price
$48
Updated
2021/12/16
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3,6-DIOXAOCTANEDIOIC ACID Chemical Properties,Usage,Production

Uses

3,6-Dioxaoctanedioic Acid (cas# 23243-68-7) is a useful research chemical.

Description

PEG2-(CH2CO2H)2 is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

3,6-Dioxaoctanedioic Acid is a useful reagent for the preparation of degradation agents for cyclin dependent kinase.

Uses

3,6-Dioxaoctanedioic acid can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Flammability and Explosibility

Not classified

Synthesis


To 15 ml (0.33 mol) of nitric acid was added at 45??C while stirring 1 g of diethylene glycol from the overall amount of 5.9 g (0.06 mol), and the mixture was heated to 65??C. After the end of nitrogen oxides evolution and cooling the mixture to 45-50??C another portion of diethylene glycol was added. Overall time of the reagent addition to the reaction mixture was 1 h. The mixture was kept at 45??C for 40 min and then it was heated at 80??C for 30 min. The solvent was removed in a vacuum at 70??C, the residue was dried by azeotropic distillation with benzene using Dean-Stark trap, then the product was fi ltered off and recrystallized from acetone-benzene mixture. 3,6-Dioxaoctanedioic acid (VIII) was similarly obtained. Yield 7.3 g (89%), colorless crystals. Rf 0.20 (E), mp 76-77??C (mp 75-76??C [13]). IR spectrum, |í, cm-1: 3167 (OH), 2914 (CH), 1733 (C=O acid), 1410, 1229 (C-O), 1121 (C-O). Mass spectrum, m/z (Irel, %): 178.5 [M]+ (76), 200.9 (55), 216.8 (46).

3,6-DIOXAOCTANEDIOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3,6-DIOXAOCTANEDIOIC ACID manufacturers

Shanghai Rlavie Technology Co ltd
Product
3,6-Dioxaoctanedioic acid 23243-68-7
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
97%minHNMR
Supply Ability
50kgs/month
Release date
2021-11-04
Career Henan Chemical Co
Product
3,6-DIOXAOCTANEDIOIC ACID 23243-68-7
Price
US $1.00/g
Min. Order
1g
Purity
99.0%
Supply Ability
100 kg
Release date
2020-01-10

23243-68-7, 3,6-DIOXAOCTANEDIOIC ACIDRelated Search:

HOOCCH2O-PEG7-CH2COOH HOOCCH2O-PEG6-CH2COOH HOOCCH2O-PEG10-CH2COOH CH2COOH-PEG12-CH2COOH Diglycolic acid HOOCCH2O-PEG8-CH2COOH 3,6,9-TRIOXAUNDECANEDIOIC ACID PEG5-(CH2CO2H)2 [1,2-ethanediylbis(oxy-2,1-ethanediyloxy)]-bis- PEG6-(CH2CO2H)2 COOH-CH2-PEG10-CH2-COOH 3,6-DIOXAOCTANEDIOIC ACID 3,6-DIOXAOCTANEDIOIC ACID DIMETHYL PERFLUORO-3,6-DIOXAOCTANE-1,8-DIOATE PERFLUORO-3,6-DIOXAOCTANE-1,8-DIOIC ACID (2R,3R,5R,6R)-1,4-DIOXANE-2,3-DICARBOXYLIC ACID, 5,6-DIMETHOXY-5,6-DIMETHYL, DIMETHYL ESTER (5R,6R)-1,4-DIOX-2-ENE-2,3-DICARBOXYLIC ACID, 5,6-DIMETHOXY-5,6-DIMETHYL DIMETHYL ESTER

  • 3,6-Dioxaoctanedioic acid CAS
  • 3,6-Dioxasuberic acid
  • Acetic acid, 2,2'-[1,2-ethanediylbis(oxy)]bis- (Triglycolic acid)
  • Acetic acid, 2,2‘-[1,2-ethanediylbis(oxy)]bis-
  • (2-CARBOXYMETHOXYETHOXY)ACETIC ACID
  • 2,2'-(Ethane-1,2-diylbis(oxy))diacetic acid
  • 3,6-dioxoctanedioic acid
  • PEG2-(CH2CO2H)2
  • 2-[2-(Carboxymethyloxy)ethoxy]acetic acid
  • 2,2'-[ethylenebis(oxy)] bisacetic acid for synthesis
  • 2,2'-[ethylenebis(oxy)]bisacetic acid
  • 2,2′-(Ethylenbis(oxy))bisessigsure
  • 3,6-Dioxaoctandioic acid
  • DOODA
  • (Ethylenebisoxy)diacetic acid
  • 2,2'-(Ethylenebisoxy)diacetic acid
  • 2,2'-[1,2-Ethanediylbis(oxy)]diacetic acid
  • 1,2-Bis(carboxymethoxy)ethane
  • 2,5-Dioxa-1,6-hexanedicarboxylic acid
  • 3,6-Dioxaoctane-1,8-dioic acid
  • 3,6-dioxa-1,8-octanedioic acid
  • HOOCCH2O-PEG1-CH2COOH
  • 2-[2-(carboxymethoxy)ethoxy]aceticaci
  • 3, 6-dioxyoctaneic acid
  • HOOCCH2O-PEG1-CH2COOH/Acetic acid, 2,2'-[1,2-ethanediylbis(oxy)]bis-
  • 23243-68-7
  • -CH2OCH2CO2H2
  • peg