PEG6-(CH2CO2H)2

Product Name: PEG6-(CH2CO2H)2
CAS No.: 77855-76-6
Chemical Name: PEG6-(CH2CO2H)2
Synonyms: CAS_77855-76-6;PEG6-(CH2CO2H)2;HOOCCH2O-PEG5-CH2COOH;COOH-CH2-PEG5-CH2-COOH;COOH-CH2-PEG5-OCH2COOH;PEG6-(CH2CO2H)2, 10 mM in DMSO;3,6,9,12,15,18-hexaoxaicosanedioic acid;3,6,9,12,15,18-Hexaoxaeicosanedioic acid;3,6,9,12,15,18-Hexaoxaicosane-1,20-dioic acid;HOOCCH2O-PEG5-CH2COOH/3,6,9,12,15,18-Hexaoxaeicosanedioic acid
CBNumber: CB13163101
Molecular Formula: C14H26O10
Formula Weight: 354.35
MOL File: 77855-76-6.mol

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PEG6-(CH2CO2H)2 Property

Boiling point:: 524.8±45.0 °C(Predicted)
Density: 1.234±0.06 g/cm3(Predicted)
storage temp.: Store at Room Tem.
solubility: Soluble in Water
pka: 3.09±0.10(Predicted)
form: Oil
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23337
Product name: PEG6-(CH2CO2H)2
Purity: 98%
Packaging: 250mg
Price: $350
Updated: 2021/12/16

Activate Scientific

Product number: AS104218
Product name: HOOCCH2O-PEG5-CH2COOH
Purity: 95+%
Packaging: 1g
Price: $471
Updated: 2021/12/16

BroadPharm

Product number: BP-23337
Product name: PEG6-(CH2CO2H)2
Purity: 98%
Packaging: 500mg
Price: $480
Updated: 2021/12/16

BroadPharm

Product number: BP-23337
Product name: PEG6-(CH2CO2H)2
Purity: 98%
Packaging: 1g
Price: $780
Updated: 2021/12/16

BroadPharm

Product number: BP-23337
Product name: PEG6-(CH2CO2H)2
Purity: 98%
Packaging: 5G
Price: $1900
Updated: 2021/12/16

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PEG6-(CH2CO2H)2 Chemical Properties,Usage,Production

Description

PEG6-(CH2CO2H)2 is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

PEG6-(CH2CO2H)2 is a symmetric PEG PROTAC linker, for the synthesis of Homo-PROTACs which is bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation[1].

IC 50

PEGs

References

[1] Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017 Oct 10;8(1):830. DOI:10.1038/s41467-017-00954-1

PEG6-(CH2CO2H)2 Preparation Products And Raw materials

Raw materials

Preparation Products

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PEG6-(CH2CO2H)2 Suppliers

China 51 United States 3 Global 54

Chengdu Pukang Biotechnology Co., Ltd

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77855-76-6, PEG6-(CH2CO2H)2Related Search:

3,6-DIOXAOCTANEDIOIC ACID BETA-ESTRADIOL 17-ACETATE BUPIRIMATE HOOCCH2O-PEG7-CH2COOH HOOCCH2O-PEG6-CH2COOH HOOCCH2O-PEG10-CH2COOH CH2COOH-PEG12-CH2COOH Diglycolic acid HOOCCH2O-PEG8-CH2COOH Peg6-(ch2co2t-butyl)2 Azido-PEG1-CH2CO2tBu Azido-PEG4-t-butyl acetate Bromo-PEG2-CH2CO2tBu Hydroxy-PEG6-CH2CO2tBu 3,6,9-TRIOXAUNDECANEDIOIC ACID PEG5-(CH2CO2H)2 [1,2-ethanediylbis(oxy-2,1-ethanediyloxy)]-bis- COOH-CH2-PEG10-CH2-COOH

PEG6-(CH2CO2H)2

HOOCCH2O-PEG5-CH2COOH

3,6,9,12,15,18-Hexaoxaeicosanedioic acid

CAS_77855-76-6

COOH-CH2-PEG5-CH2-COOH

3,6,9,12,15,18-hexaoxaicosanedioic acid

3,6,9,12,15,18-Hexaoxaicosane-1,20-dioic acid

PEG6 (CH2CO2H)2,PROTAC Linkers,PEG-6-(CH2CO2H)2,PEG6-(CH2CO2H)2,PEG6(CH2CO2H)2,inhibit,Inhibitor

HOOCCH2O-PEG5-CH2COOH/3,6,9,12,15,18-Hexaoxaeicosanedioic acid

PEG6-(CH2CO2H)2, 10 mM in DMSO

COOH-CH2-PEG5-OCH2COOH

77855-76-6

PROTAC LINKER