Azido-PEG1-CH2CO2tBu
- Product Name
- Azido-PEG1-CH2CO2tBu
- CAS No.
- 1820717-35-8
- Chemical Name
- Azido-PEG1-CH2CO2tBu
- Synonyms
- CAS_1820717-35-8;Azido-PEG1-C1-Boc;Azido-PEG1-CH2COOtBu;Azido-PEG1-CH2CO2tBu;Azido-PEG1-t-butyl acetate;Azido-PEG1-CH2COOH t-Bu Ester;Azido-PEG1-CH2CO2-t-butyl ester;tert-Butyl 2-(2-azidoethoxy)acetate;Azido-PEG1-CH2CO2-t-Bu,Azido-PEG1-CH2CO2-t-butyl Ester
- CBNumber
- CB83162860
- Molecular Formula
- C8H15N3O3
- Formula Weight
- 201.23
- MOL File
- 1820717-35-8.mol
Azido-PEG1-CH2CO2tBu Property
- storage temp.
- Store at Room Tem.
- solubility
- Soluble in DCM, DMF
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A965980
- Product name
- Azido-PEG1-CH2CO2-t-butylEster
- Packaging
- 5mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- BP-22060
- Product name
- Azido-PEG1-CH2CO2-t-Bu
- Purity
- 98%
- Packaging
- 250mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- B-0921
- Product name
- tert-Butyl2-(2-azidoethoxy)acetate
- Purity
- 97%
- Packaging
- 1g
- Price
- $495
- Updated
- 2021/12/16
Azido-PEG1-CH2CO2tBu Chemical Properties,Usage,Production
Description
Azido-PEG1-CH2CO2-t-Bu is a azide (N3) containing PEG linker.The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Azido-PEG1-C1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1-C1-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG1-CH2CO2tBu Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG1-CH2CO2tBu Suppliers
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