Bromo-PEG2-CH2CO2tBu

Product Name: Bromo-PEG2-CH2CO2tBu
CAS No.: 1807518-63-3
Chemical Name: Bromo-PEG2-CH2CO2tBu
Synonyms: Br-PEG2-CH2-Boc;CAS_1807518-63-3;Br-PEG2-CH2COOtBu;Bromo-PEG2-CH2-Boc;Bromo-PEG2-CH2COOtBu;Bromo-PEG2-CH2CO2tBu;t-butyl acetate-PEG2-bromide;t-butyl acetate-PEG2-bromiade;tert-Butyl 2-[2-(2-bromoethoxy)ethoxy]acetate;t-butyl acetate-PEG2-bromide BROMO-PEG2-CH2CO2TBU
CBNumber: CB73062440
Molecular Formula: C10H19BrO4
Formula Weight: 283.16
MOL File: 1807518-63-3.mol

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Bromo-PEG2-CH2CO2tBu Property

Boiling point:: 316.4±22.0 °C(Predicted)
Density: 1.269±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
form: liquid
color: Clear

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Safety

HS Code: 2942000090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22261
Product name: Bromo-PEG2-CH2CO2tBu
Purity: 98%
Packaging: 100mg
Price: $340
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1339
Product name: Bromo-PEG2-CH2CO2tBu
Packaging: 100mg
Price: $731
Updated: 2021/12/16

Acrotein

Product number: B-0862
Product name: Br-PEG2-CH2COOtBu
Purity: 97%
Packaging: 0.25g
Price: $201.66
Updated: 2021/12/16

Acrotein

Product number: B-0862
Product name: Br-PEG2-CH2COOtBu
Purity: 97%
Packaging: 0.5g
Price: $302.5
Updated: 2021/12/16

Acrotein

Product number: B-0862
Product name: Br-PEG2-CH2COOtBu
Purity: 97%
Packaging: 1g
Price: $458.34
Updated: 2021/12/16

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Bromo-PEG2-CH2CO2tBu Chemical Properties,Usage,Production

Description

Bromo-PEG2-CH2CO2tBu is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Bromo-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Bromo-PEG2-CH2CO2tBu Preparation Products And Raw materials

Raw materials

Preparation Products

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Bromo-PEG2-CH2CO2tBu Suppliers

China 57 United Kingdom 1 United States 5 Global 63

T&W GROUP

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Shanghai YuanYe Biotechnology Co., Ltd.

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1807518-63-3, Bromo-PEG2-CH2CO2tBuRelated Search:

Tetrabutyl titanate TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA H2N-PEG8-tBu Bromo-PEG4-CH2COOtBu Amino-PEG10-t-butyl ester AMINO-PEG12-T-BUTYL ESTER H2N-PEG6-tBu Bromo-PEG1-CH2CO2tBu Amino-PEG5-t-butyl ester H2N-PEG2-tBu Bromo-PEG4-t-butyl ester Bromo-PEG2-t-butyl ester H2N-PEG4-tBu Azido-PEG1-CH2CO2tBu Azido-PEG4-t-butyl acetate PEG6-(CH2CO2H)2 Hydroxy-PEG6-CH2CO2tBu Hydroxy-PEG1-CH2CO2tBu

Bromo-PEG2-CH2CO2tBu

Bromo-PEG2-CH2COOtBu

t-butyl acetate-PEG2-bromiade

Br-PEG2-CH2COOtBu

t-butyl acetate-PEG2-bromide

CAS_1807518-63-3

tert-Butyl 2-[2-(2-bromoethoxy)ethoxy]acetate

Bromo-PEG2-CH2-Boc

t-butyl acetate-PEG2-bromide BROMO-PEG2-CH2CO2TBU

Bromo-PEG-2-CH2-Boc,BromoPEG2CH2Boc,inhibit,Bromo PEG2 CH2 Boc,PROTAC Linkers,Inhibitor

Br-PEG2-CH2COOtBu/Acetic acid, 2-[2-(2-bromoethoxy)ethoxy]-, 1,1-dimethylethyl ester

Br-PEG2-CH2-Boc

Acetic acid, 2-[2-(2-bromoethoxy)ethoxy]-, 1,1-dimethylethyl ester

1807518-63-3