ChemicalBook > CAS DataBase List > H2N-PEG8-tBu

H2N-PEG8-tBu

Product Name
H2N-PEG8-tBu
CAS No.
756526-06-4
Chemical Name
H2N-PEG8-tBu
Synonyms
tert-butyl 1-amino-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate;Amino-PEG8-t-butyl ester;H2N-PEG8-tBu;Amino-PEG8-Boc;NH2-PEG8-COOtBu;Amino-PEG8-COOtBu;NH2-PEG8-CH2COOtBu;NH2-PEG8-C2-COOtBu;COOtBu-PEG8-C2-NH2;NH2-PEG8-CH2CH2COOtBu
CBNumber
CB62546874
Molecular Formula
C23H47NO10
Formula Weight
497.62
MOL File
756526-06-4.mol
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H2N-PEG8-tBu Property

Boiling point:
544.3±45.0 °C(Predicted)
Density 
1.067±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
solubility 
Soluble in Water, DMSO, DCM, DMF
form 
Oil
pka
8.74±0.10(Predicted)
color 
Colorless to light yellow
InChI
InChI=1S/C23H47NO10/c1-23(2,3)34-22(25)4-6-26-8-10-28-12-14-30-16-18-32-20-21-33-19-17-31-15-13-29-11-9-27-7-5-24/h4-21,24H2,1-3H3
InChIKey
UMJVFHNJPJVDSB-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN
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Safety

HS Code 
2942000090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Apolloscientific
Product number
BIPG1076
Product name
Amino-PEG8-t-butylester
Packaging
100mg
Price
$106
Updated
2021/12/16
ChemScene
Product number
CS-0031590
Product name
Amino-PEG8-Boc
Purity
≥97.0%
Packaging
100mg
Price
$120
Updated
2021/12/16
ChemScene
Product number
CS-0031590
Product name
Amino-PEG8-Boc
Purity
≥97.0%
Packaging
250mg
Price
$199
Updated
2021/12/16
Apolloscientific
Product number
BIPG1076
Product name
Amino-PEG8-t-butylester
Packaging
250mg
Price
$238
Updated
2021/12/16
BroadPharm
Product number
BP-21119
Product name
Amino-PEG8-t-butylester
Purity
98%
Packaging
250mg
Price
$280
Updated
2021/12/16
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H2N-PEG8-tBu Chemical Properties,Usage,Production

Description

Amino-PEG8-t-butyl ester is a monodisperse PEG linker containing an amino group with a t-butyl protected carboxyl group.The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

H2N-PEG8-tBu is a cleavable 8-unit PEG-ADC linker for antibody drug conjugate (ADC) synthesis.

IC 50

Cleavable Linker; Alkyl/ether; PEGs

H2N-PEG8-tBu Preparation Products And Raw materials

Raw materials

Preparation Products

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H2N-PEG8-tBu Suppliers

China 123 India 1 United Kingdom 1 United States 8 Global 133
LAURENT.INC
Tel
17721037897
Email
sun@laurentpeg.com
Country
China
ProdList
490
Advantage
58
Guangzhou Hongyuan Chemical Co.,Ltd
Tel
15817493340
Email
981810490@qq.com
Country
China
ProdList
1566
Advantage
58
Changsha Morning Shine Co., Ltd.
Tel
189-75832125 13397510867
Email
BD@csmspharm.com
Country
China
ProdList
522
Advantage
58
Henan Mengtai Pharmaceutical Technology Co., Ltd
Tel
17634413542 17634854698;
Email
1959525201@qq.com
Country
China
ProdList
9999
Advantage
58
CHENGDU YINGNUOLING PHARMACEUTICAL TECHNOLOGY CO.,LTD
Tel
17882285575
Email
1276966012@qq.com
Country
China
ProdList
397
Advantage
58
Shanghai Huici Pharmaceutical Technology Co., LTD
Tel
133-31922809 19372841038
Email
lixing@pharmahuici.com
Country
China
ProdList
845
Advantage
58
Chemyouth Life Science（Suzhou）Co.,Ltd
Tel
18605123100
Email
kaiyuezhang@chemyouth.com
Country
China
ProdList
143
Advantage
58
HANGZHOU LAURET BIOTECHOLOGY CO.,LTD
Tel
15306536782
Email
3839324846@qq.com
Country
China
ProdList
149
Advantage
58
Suzhou Highfine Biotech Co., Ltd
Tel
0512-69209928;68417696 18306209966;13962195629
Email
linda@highfine.com;minhan.zhao@highfine.com
Country
China
ProdList
1639
Advantage
58
Biomatrik (Jiaxing) Inc.
Tel
0573-82623377 18967387295
Fax
+86 (573) 8262-3317
Email
sales@biomatrik.cn
Country
China
ProdList
50
Advantage
61
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View Lastest Price from H2N-PEG8-tBu manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
NH2-PEG8-COOtBu 756526-06-4
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2026-02-06
LAURENT
Product
NH2-PEG8-CH2CH2COOtBu 756526-06-4
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2026-01-29
XIAMEN SINOPEG BIOTECH CO., LTD.
Product
tert-butyl 1-amino-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate 756526-06-4
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
756526-06-4
Release date
2025-09-12

756526-06-4, H2N-PEG8-tBuRelated Search:

N3-PEG3-tBu 20-Azido-3,6,9,12,15,18-hexaoxaeicosan-1-amine 17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine H2N-PEG6-tBu AMINO-PEG12-T-BUTYL ESTER Amino-PEG8-azide 3,6,9,12,15-PENTAOXAHEPTADECANE-1,17-DIYL BIS-AZIDE N3-PEG4-tBu O-(2-AMINOETHYL)-O-(2-AZIDOETHYL)NONAETHYLENE GLYCOL 3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID 5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid,1-(9-fluren-9-ylmethyl)ester FMoc-NH-PEG9-CH2CH2COOH Fmoc-9-Amino-4,7-Dioxanonanoic acid 3,6,9,12-tetraoxatridecylamine HO-PEG8-CH2CH2COOH 5,8,11-Trioxa-2-azatridecanoic,13-amino,1,1-dimethylethyl ester Azido-PEG11-azide

  • Amino-PEG9-t-butyl ester
  • H<sub>2</sub>N-PEG<sub>8</sub>-CH<sub>2</sub>CH<sub>2</sub>COO<sup>t</sup>Bu
  • H2N-PEG8-tBu
  • 27-Amino-4,7,10,13,16,19,22,25-octaoxaheptacosanoic acid 1,1-dimethylethyl ester
  • H2N-PEG8-CH2CH2COOtBu
  • Amino-PEG8-t-butyl ester
  • NH2-PEG8-CH2CH2COOtBu
  • tert-butyl 1-amino-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
  • Amino-PEG8-COOtBu
  • Amino-PEG8-Boc
  • NH2-PEG8-t-butyl ester,Amino-PEG8-t-butyl ester
  • 4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-amino-, 1,1-dimethylethyl ester
  • amino-dPEG8.(TM).-t-butyl ester
  • NH2-PEG8-CH2COOtBu
  • Amino-PEG8-t-Bu Ester
  • NH2-PEG8-C2-COOtBu
  • tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
  • Amino-PEG8-tert-Butyl Ester
  • Amino-dPEG??-t-butyl ester (QBD-10271)
  • NH2-PEG8-COOtBu
  • Acyclovir Impurity 52
  • COOtBu-PEG8-C2-NH2
  • 756526-06-4
  • C23H47NO10
  • peg
  • Linker