BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID
- Product Name
- BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID
- CAS No.
- 882847-13-4
- Chemical Name
- BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID
- Synonyms
- Boc-NH-PEG6-COOH;BocNH-PEG6-C2-COOH;Boc-N-amido-PEG6-acid;Boc-NH-PEG6-CH2CH2COOH;t-Boc-N-amido-PEG7-acid;t-Boc-N-amido-PEG6-acid;T-BOC-NH-AMIDO-PEG6-COOH;Boc-NH-PEG6-Propionic Acid;Boc-NH-(PEG)-COOH (22 atoms);t-boc-N-amido-PEG6-propionic acid
- CBNumber
- CB6359597
- Molecular Formula
- C20H39NO10
- Formula Weight
- 453.52
- MOL File
- 882847-13-4.mol
BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID Property
- storage temp.
- 2-8°C
- solubility
- Soluble in DMSO
- form
- clear liquid
- color
- Colorless to Light yellow to Light orange
- InChI
- InChI=1S/C20H39NO10/c1-20(2,3)31-19(24)21-5-7-26-9-11-28-13-15-30-17-16-29-14-12-27-10-8-25-6-4-18(22)23/h4-17H2,1-3H3,(H,21,24)(H,22,23)
- InChIKey
- FTTYOIHYERRXQB-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)NCCOCCOCCOCCOCCOCCOCCC(O)=O
Safety
- WGK Germany
- 3
- HS Code
- 29225090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 8.51041
- Product name
- Boc-NH-(PEG)₅-COOH (22 atoms)
- Purity
- Novabiochem?
- Packaging
- 1g
- Price
- $345
- Updated
- 2025/07/31
- Product number
- 38263
- Product name
- 21-(Boc-amino)-4,7,10,13,16,19-hexaoxaheneicosanoic acid
- Purity
- purum, ≥97.0% (H-NMR)
- Packaging
- 100mg
- Price
- $96.5
- Updated
- 2023/01/07
- Product number
- B5651
- Product name
- 21-[(tert-Butoxycarbonyl)amino]-4,7,10,13,16,19-hexaoxaheneicosanoic Acid
- Purity
- >98.0%(HPLC)
- Packaging
- 250mg
- Price
- $169
- Updated
- 2025/07/31
- Product number
- 265927
- Product name
- Boc-21-amino-4,7,10,13,16,19-hexaoxaheneicosanoic acid
- Packaging
- 25mg
- Price
- $333
- Updated
- 2021/12/16
- Product number
- FB52563
- Product name
- Boc-21-amino-4,7,10,13,16,19-hexaoxaheneicosanoic acid
- Packaging
- 50mg
- Price
- $120
- Updated
- 2021/12/16
BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID Chemical Properties,Usage,Production
Description
t-Boc-N-amido-PEG6-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Chemical Properties
Yellow liquid
Uses
Boc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC). Boc-NH-PEG6-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
reaction suitability
reaction type: Pegylations
reagent type: cross-linking reagent
IC 50
Cleavable Linker; Alkyl/ether; PEGs
References
[1] Michael J. Mcpherson, et al. Glucocorticoid receptor agonist and immunoconjugates thereof. WO2017210471A1.
BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID manufacturers
- Product
- BocNH-PEG6-CH2CH2COOH 882847-13-4
- Price
- US $149.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2025-11-15
- Product
- 2,2-dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azahexacosan-26-oic acid 882847-13-4
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-12
- Product
- t-Boc-N-amido-PEG6-acid 882847-13-4
- Price
- US $0.00/g
- Min. Order
- 10g
- Purity
- >98.00%
- Supply Ability
- 10g
- Release date
- 2024-03-25