ChemicalBook > CAS DataBase List > BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID

BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID

Product Name
BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID
CAS No.
882847-13-4
Chemical Name
BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID
Synonyms
Boc-NH-PEG6-COOH;BocNH-PEG6-C2-COOH;Boc-N-amido-PEG6-acid;Boc-NH-PEG6-CH2CH2COOH;t-Boc-N-amido-PEG7-acid;t-Boc-N-amido-PEG6-acid;T-BOC-NH-AMIDO-PEG6-COOH;Boc-NH-PEG6-Propionic Acid;Boc-NH-(PEG)-COOH (22 atoms);t-boc-N-amido-PEG6-propionic acid
CBNumber
CB6359597
Molecular Formula
C20H39NO10
Formula Weight
453.52
MOL File
882847-13-4.mol
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BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID Property

storage temp. 
2-8°C
solubility 
Soluble in DMSO
form 
clear liquid
color 
Colorless to Light yellow to Light orange
InChI
InChI=1S/C20H39NO10/c1-20(2,3)31-19(24)21-5-7-26-9-11-28-13-15-30-17-16-29-14-12-27-10-8-25-6-4-18(22)23/h4-17H2,1-3H3,(H,21,24)(H,22,23)
InChIKey
FTTYOIHYERRXQB-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)NCCOCCOCCOCCOCCOCCOCCC(O)=O
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Safety

WGK Germany 
3
HS Code 
29225090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.51041
Product name
Boc-NH-(PEG)₅-COOH (22 atoms)
Purity
Novabiochem?
Packaging
1g
Price
$345
Updated
2025/07/31
Sigma-Aldrich
Product number
38263
Product name
21-(Boc-amino)-4,7,10,13,16,19-hexaoxaheneicosanoic acid
Purity
purum, ≥97.0% (H-NMR)
Packaging
100mg
Price
$96.5
Updated
2023/01/07
TCI Chemical
Product number
B5651
Product name
21-[(tert-Butoxycarbonyl)amino]-4,7,10,13,16,19-hexaoxaheneicosanoic Acid
Purity
>98.0%(HPLC)
Packaging
250mg
Price
$169
Updated
2025/07/31
Usbiological
Product number
265927
Product name
Boc-21-amino-4,7,10,13,16,19-hexaoxaheneicosanoic acid
Packaging
25mg
Price
$333
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB52563
Product name
Boc-21-amino-4,7,10,13,16,19-hexaoxaheneicosanoic acid
Packaging
50mg
Price
$120
Updated
2021/12/16
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BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID Chemical Properties,Usage,Production

Description

t-Boc-N-amido-PEG6-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Chemical Properties

Yellow liquid

Uses

Boc-NH-PEG6-CH2CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC). Boc-NH-PEG6-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

reaction suitability

reaction type: Pegylations
reagent type: cross-linking reagent

IC 50

Cleavable Linker; Alkyl/ether; PEGs

References

[1] Michael J. Mcpherson, et al. Glucocorticoid receptor agonist and immunoconjugates thereof. WO2017210471A1.

BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID Suppliers

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View Lastest Price from BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID manufacturers

LAURENT
Product
BocNH-PEG6-CH2CH2COOH 882847-13-4
Price
US $149.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-15
XIAMEN SINOPEG BIOTECH CO., LTD.
Product
2,2-dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azahexacosan-26-oic acid 882847-13-4
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2025-09-12
Xian confluore Biological Technology Co., Ltd.
Product
t-Boc-N-amido-PEG6-acid 882847-13-4
Price
US $0.00/g
Min. Order
10g
Purity
>98.00%
Supply Ability
10g
Release date
2024-03-25

882847-13-4, BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACIDRelated Search:

t-Boc-N-amido-PEG15-acid t-Boc-N-amido-PEG10-acid O-[2-(Boc-amino)ethyl]-Oμ-(2-carboxyethyl)polyethylene glycol 3,000 O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL t-Boc-N-amido-PEG5-acid Boc-9-AMino-4,7-Dioxanonanoic acid t-boc-N-amido-PEG14-amine O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) t-Boc-N-amido-PEG17-acid t-boc-N-amido-PEG13-amine t-Boc-N-amido-PEG2-acid t-Boc-N-amido-PEG14-acid t-boc-N-amido-PEG16-amine t-Boc-N-amido-PEG11-acid 22-Amino-5,8,11,14,17,20-hexaoxa-2-azadocosanoic acid 1,1-dimethylethyl ester N-BOC-AMINOEHTOXY-ETHOXY-ETHOXY-ETHANOL BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID (2-[2-(2-HYDROXY-ETHOXY)-ETHOXY]-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER

  • Boc-NH-(PEG)-COOH (22 atoms)
  • 5,8,11,14,17,20-Hexaoxa-2-azatricosanedioic acid 1-(1,1-dimethylethyl) ester
  • t-Boc-N-amido-PEG6-acid
  • t-Boc-N-amido-PEG7-acid
  • Boc-N-amido-PEG6-acid
  • t-boc-N-amido-PEG6-propionic acid
  • Boc-NH-(PEG)-COOH (22 atoms) Novabiochem
  • BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID
  • Boc-NH-PEG6-CH2CH2COOH
  • 21-(Boc-aMino)-4,7,10,13,16,19-hexaoxaheneicosanoic acid
  • Boc-NH-PEG6-COOH
  • T-BOC-NH-AMIDO-PEG6-COOH
  • 21-[(tert-Butoxycarbonyl)amino]-4,7,10,13,16,19-hexaoxaheneicosanoic Acid
  • 2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azahexacosan-26-oic Acid
  • BocNH-PEG6-CH2CH2COOH/5,8,11,14,17,20-Hexaoxa-2-azatricosanedioic acid, 1-(1,1-dimethylethyl) ester
  • BocNH-PEG6-C2-COOH
  • 3-[2-[2-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
  • Boc-NH-PEG6-Propionic Acid
  • 882847-13-4
  • C20H39NO10
  • peg